Gene name:
Myo16 (Kiaa0865;Nyap3) ;
Protein name:
Myosin-XVI ;
Alternative:
Unconventional myosin-16 ;Unconventional myosin-16 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Binds PPP1CA and/or PPP1CC. Binds F-actin in an ATP-sensitive manner.
Function:
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development.
Subcellular Location:
Cytoplasm
Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells.
Protein Attributes:
50:
MEIDQCLLES | LPLGQRQRLV | KRMRCEQIKA | YYEREKVFQK | QEGPLKRSKP |
100:
GKRQKVRFGL | ADMIQDAVIH | HHDKEVLQLL | KEGADPHTLV | SSGGSLLHLC |
150:
ARYDNVFIAE | VLIDRGVNVN | HQDEDFWTPM | HIACACDNPD | IVLLLILAGA |
200:
NVFLQDVNGN | IPLDYAVEGT | ESSAILLAYL | DEKGVDLSSL | RQIKLQRPLS |
250:
MLTDVRHFLS | SGGDVNEKND | DGVTLLHMAC | ASGYKEVVLL | LLEHGGDLNG |
300:
TDDRYWTPLH | LAAKYGQTTL | VKLLLAHQAN | PHLVNCNGEK | PSDIAASESI |
350:
EEMLLKAEIA | WEEKMKESPS | APSLAQEELY | EILHDLPDLS | SKLSPLVLPI |
400:
AKQDSLLEKD | IMFKDTTKGL | CKQESQDGPP | ETSMTSNCGK | PEQVQVMPPA |
450:
PSDDLATLSE | LNDSSLLYEI | QKRFGNDQIH | TFIGDIFLLV | NPFKELPIYS |
500:
TMVSQMYLSP | TGQRSPSLPP | HLFSCAERAF | HRLFQERKPQ | NIILSGERGS |
550:
GKTQASKQIM | KYLTSRASSS | CTMFDSRLRH | AIYIVEAFGH | AKTTLNNVSS |
600:
CLIQYWELQC | CQRRKHITGA | RISTYMLEKS | RVVAQPPGQG | TFLIFSWLMD |
650:
GLSSEEKCGL | HLNNFCAHRY | VSQGMREDVS | TAEHSLNKER | LAALKHALNV |
700:
IGFSTLEVEN | LFVILSAILH | IGDIQFTALT | EADSAFVSDL | QLLEQVAGML |
750:
QVSTDELASA | LTTDIQYFKG | DVIIRRHTIQ | MAAFYRDLLA | KSLYSRLFGF |
800:
LINTVNCCLQ | NQDEYKSLQT | LDIGILDIFG | FEEFQKNEFE | QLCVNLTNEK |
850:
MHHYIQEVLF | LQEQTECVQE | GVAMETACSP | GNQAGVLDFF | FQKPSGFFSL |
900:
LDEESQVIWS | GEPNLPRKLQ | GLLESSNTNA | VYSPVKDGNG | NVAFKGQGAA |
950:
FTVMHYAGRV | MYEMGGAVER | NKDSLSQNLL | FVMKTSENVV | ISHLFQSKLS |
1000:
QTGSLISSYP | SFKFGGHKST | LLSKRTASSM | VGVNKNYLEL | SKLLKKKGTS |
1050:
TFLQRLERGE | PATAASQLTK | SLADITAKLQ | RGSPHFILCI | KPNTSQLPGV |
1100:
FDHFYVSAQL | QYLGVLGLVR | LFRSGYPVRP | SFEDFLSRYE | PLASVLLGET |
1150:
KGQAAEERCR | LVLQRCKLQG | WQIGVHKVFL | KYWHVDQLSD | LWLQLQRKIV |
1200:
TCQKVIRGFL | ARQHLLQRMS | IKQQEVTSIK | SFLQSTEDMA | LKTYDALVIQ |
1250:
NASDIAREHD | RLRKEVHTAY | HRNRQEEGTK | RAEDQGGCRH | VHSNSVPVPM |
1300:
VVDSLAQALT | GPSTRPPSLH | SVFSMDDSTG | LPSPRKQPPP | KPKRDPNTRL |
1350:
SASYEAVSAC | LSAAKDAAGE | ALTRPRPHSD | DYSTMKKIPP | RKPKRSPHTK |
1400:
LSGSYEEIWG | PPRPSGTMGQ | GGRHQAPGTL | SVQWARPDSV | PQCTPQLPLH |
1450:
LPLPQGDYDD | DAEPVYIEMV | GNAARAGGSE | TDSPDQGESV | YEEMKYILPE |
1500:
EGCGLGMLTF | LPASPPLFLE | TRKAIILEAA | EGNCQPSKDT | CDIPPPFPNL |
1550:
LPHRPPLLVF | PPTPVTRSPA | SDESPLTPLE | VKKLPVLETN | LKYPVQSEGS |
1600:
SPLSPQYSKA | QKGDNDQLAS | PGFPVFNGPS | RISPPATPPP | PPGPPPAPCG |
1650:
PPPAPCGPPP | APCGPPPAPC | GPPPAPCGPP | PAPCGAASAS | CGVAPAPCRP |
1700:
PTHFAFPPES | VLVTAAKALT | NSDLPRTQPK | PSSAPVPGPC | SSFVKAPYSP |
1750:
GKTARADLRK | TSSTFSPPSP | YSPPNSRPLS | SPLDELASLF | NSGRSVLRRS |
1800:
AVGRRIREAE | GFETNMNLSS | RDEPSSSEMA | SETQDRNANN | HGTQLSSSLS |
1850:
SDVTAENGNP | VTNGLAEDDG | CSRLCLSGMG | TSSFQRNRES | HTTQVIHQLR |
1900:
LSENESVALQ | ELLDWRRKLC | EAREGWQEAL | QHPEPRAPPP | PPCKKPTLLK |
1919:
KPEGGSCTRL | PSQLWDSSM
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
ELISA Kit for Mouse Myosin-XVI
ELISA Kit for Mouse Myosin-XVI
ELISA Kit for Mouse Myosin-XVI
CLIA Kit for Mouse Myosin-XVI
CLIA Kit for Mouse Myosin-XVI
CLIA Kit for Mouse Myosin-XVI
Polyclonal Antibody for Mouse Myosin-XVI
Polyclonal Antibody for Mouse Myosin-XVI
Polyclonal Antibody for Mouse Myosin-XVI
Monoclonal Antibody for Mouse Myosin-XVI
Monoclonal Antibody for Mouse Myosin-XVI
Monoclonal Antibody for Mouse Myosin-XVI
Protein for Mouse Myosin-XVI
Protein for Mouse Myosin-XVI
Protein for Mouse Myosin-XVI
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons."
Yokoyama K.
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EMBO J.30:4739-4754(2011)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);FUNCTION;INTERACTION WITH ACOT9; ARHGAP26; CYFIP1; NCKAP1 AND PIK3R2;SUBUNIT;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE;PHOSPHORYLATION;MUTAGENESIS OF TYR-1416 AND TYR-1441
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6 .
tissue :
Brain .
tissue :
Testis .
3.
"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-992 (ISOFORM 1)
strain :
C57BL/6J .
tissue :
Cerebellum .
4.
"Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N.
,
Kikuno R.F.
,
Ohara R.
,
Inamoto S.
,
Nagase T.
,
Ohara O.
,
Koga H.
Submitted (2005-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 736-1919
tissue :
Fetal brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Brain .