Myo1c ELISA Kit for Rat(Rattus norvegicus) | EIAab.comMyo1c ELISA Kit for Rat(Rattus norvegicus)

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Myo1c (Gene name),

Myosin-Ic (Protein name ), MYO1C_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Myo1c(Myr2);

Protein name:

Myosin-Ic;

Alternative:

Myosin heavy chain myr 2;Myosin I beta(MMI-beta;MMIb);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts (via its IQ motifs) with calmodulin. Interacts with RPS6 and actin. Interacts (via its IQ motifs) with CABP1 and CIB1; the interaction with CABP1 and CIB1 is calcium-dependent. Interacts (via tail domain) with PLEKHB1 (via PH domain); the interaction is not affected by the presence or absence of calcium and calmodulin. Interacts with BAZ1B, SMARCA5, POLR1A and POLR2A. Component of the B-WICH complex, at least composed of SMARCA5/SNF2H, BAZ1B/WSTF, SF3B1, DEK, MYO1C, ERCC6, MYBBP1A and DDX21.

Function:

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes.

Subcellular Location:

Cytoplasm Cell membrane Cell projection stereocilium membrane

Protein Attributes:

Sequence length:

1044

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1044:

QGSITFAGGP | GRDGIIDFTS | GSELLITKAK | NGHLAVVAPR | LNSR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:65261

STRING:

10116.ENSRNOP00000061676

Pfam:

PF00612

UniGene:

Rn.55135

String:

Q63355

Uniprot:

Q63355

FOR

ELISA Kit for Rat Myosin-Ic

CLIA Kit for Rat Myosin-Ic

Polyclonal Antibody for Rat Myosin-Ic

Monoclonal Antibody for Rat Myosin-Ic

Protein for Rat Myosin-Ic

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"MYR-2 a novel class-I myosin identified in rat brain."
Ruppert C. , Godel J. , Reinhard J. , Baehler M.
Submitted (1993-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
2.

"Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles."
Boguslavsky S. , Chiu T. , Foley K.P. , Osorio-Fuentealba C. , Antonescu C.N. , Bayer K.U. , Bilan P.J. , Klip A.
Mol. Biol. Cell23:4065-4078(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH GLUT4

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