Myo1e ELISA Kit for Mouse(Mus musculus) | EIAab.comMyo1e ELISA Kit for Mouse(Mus musculus)

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Myo1e (Gene name),

Unconventional myosin-Ie (Protein name ), MYO1E_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Myo1e(Myr3);

Protein name:

Unconventional myosin-Ie;

Alternative:

Unconventional myosin 1E;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with CALM and F-actin. Interacts (via SH3 domain) with SYNJ1, DNM1 and DNM2 (By similarity). Interacts with ARL14EP.

Function:

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain (By similarity). Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14.

Subcellular Location:

Cytoplasm Cell junction Cytoplasmic vesicle Cytoplasmic vesicle Clathrin-coated vesicle Cytoplasm Cytoskeleton In podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with F-actin (By similarity). Detected in cytoplasmic punctae.

Protein Attributes:

Sequence length:

1107

Sequence:

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1107:

NNYVTKI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

E9Q634

Pfam:

PF00063

KEGG:

mmu:71602

UniGene:

Mm.249311

Uniprot:

E9Q634

FOR

ELISA Kit for Mouse Unconventional myosin-Ie

CLIA Kit for Mouse Unconventional myosin-Ie

Polyclonal Antibody for Mouse Unconventional myosin-Ie

Monoclonal Antibody for Mouse Unconventional myosin-Ie

Protein for Mouse Unconventional myosin-Ie

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Liver.
3.

"Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia."
Dumont R.A. , Zhao Y.-D. , Holt J.R. , Baehler M. , Gillespie P.G.
J. Assoc. Res. Otolaryngol.3:375-389(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 600-726;TISSUE SPECIFICITY
strain: C57BL/6.
4.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
5.

"Disruption of Myosin 1e promotes podocyte injury."
Krendel M. , Kim S.V. , Willinger T. , Wang T. , Kashgarian M. , Flavell R.A. , Mooseker M.S.
J. Am. Soc. Nephrol.20:86-94(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
6.

"Myosin 1E SH3 domain."
Allsop G. , Harris S.A. , Peckham M. , Edwards T.
Submitted (2011-08) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 1053-1107

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