MYO5A ELISA Kit for Human(Homo sapiens) | EIAab.comMYO5A ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MYO5A(Gene name) > Human

MYO5A (Gene name),

Myosin-Va (Protein name ), MYO5A_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MYO5A(MYH12);

Protein name:

Myosin-Va;

Alternative:

Myosin heavy chain 12;Dilute myosin heavy chain, non-muscle;Myoxin;Myosin-12;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

May be a homodimer, which associates with multiple calmodulin or myosin light chains. Binds MLPH and MYRIP.

Function:

Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. May also be required for some polarization process involved in dendrite formation.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

1855

Sequence:

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1850:

1855:

FISRV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.21213

Pfam:

PF01843

STRING:

9606.ENSP00000382177

SMR:

Q9Y4I1

MIM:

160777

KEGG:

hsa:4644

String:

Q9Y4I1

Uniprot:

Q9Y4I1

FOR

ELISA Kit for Human Myosin-Va

CLIA Kit for Human Myosin-Va

Polyclonal Antibody for Human Myosin-Va

Monoclonal Antibody for Human Myosin-Va

Protein for Human Myosin-Va

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The complete cDNA for human myosin heavy chain 12, a class V myosin."
Meurers B.H. , Zimmermann R. , Vosberg H.P.
Submitted (1996-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
tissue: Skin.
2.

"Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene."
Pastural E. , Barrat F.J. , Dufourcq-Lagelouse R. , Certain S. , Sanal O. , Jabado N. , Seger R. , Griscelli C. , Fischer A. , de Saint Basile G.
Nat. Genet.16:289-292(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT CYS-1246
3.

Pastural E. , Barrat F.J. , Dufourcq-Lagelouse R. , Certain S. , Sanal O. , Jabado N. , Seger R. , Griscelli C. , Fischer A. , de Saint Basile G.
Nat. Genet.23:373-373(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
4.

"Analysis of the DNA sequence and duplication history of human chromosome 15."
Zody M.C. , Garber M. , Sharpe T. , Young S.K. , Rowen L. , O'Neill K. , Whittaker C.A. , Kamal M. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Kodira C.D. , Madan A. , Qin S. , Yang X. , Abbasi N. , Abouelleil A. , more...
Nature440:671-675(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Cloning, analysis, and chromosomal localization of myoxin (MYH12), the human homologue to the mouse dilute gene."
Engle L.J. , Kennett R.H.
Genomics19:407-416(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 638-1477 (ISOFORM 2)
tissue: Fetal brain.
6.

"Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21."
Moore K.J. , Testa J.R. , Francke U. , Milatovich A. , Copeland N.G. , Jenkins N.A.
Cytogenet. Cell Genet.69:53-58(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1061-1498 (ISOFORM 2)
tissue: Brain.
7.

"Inhibition of dendrite formation in melanocytes transiently transfected with antisense DNA to myosin V."
Edgar A.J. , Bennett J.P.
Submitted (1998-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1358-1460 (ISOFORM 3)
8.

"Myosin-V is a processive actin-based motor."
Mehta A.D. , Rock R.S. , Rief M. , Spudich J.A. , Mooseker M.S. , Cheney R.E.
Nature400:590-593(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions."
Nagashima K. , Torii S. , Yi Z. , Igarashi M. , Okamoto K. , Takeuchi T. , Izumi T.
FEBS Lett.517:233-238(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MLPH
10.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
11.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
13.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1452;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
14.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
15.

"Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes."
Chen Y. , Wang Y. , Zhang J. , Deng Y. , Jiang L. , Song E. , Wu X.S. , Hammer J.A. , Xu T. , Lippincott-Schwartz J.
J. Cell Biol.198:545-560(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RAB10
16.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
17.

"Arg-Cys substitution at codon 1246 of the human myosin Va gene is not associated with Griscelli syndrome."
Lambert J. , Naeyaert J.-M. , De Paepe A. , Van Coster R. , Ferster A. , Song M. , Messiaen L.
J. Invest. Dermatol.114:731-733(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CYS-1246
18.

"Two genes are responsible for Griscelli syndrome at the same 15q21 locus."
Pastural E. , Ersoy F. , Yalman N. , Wulffraat N. , Grillo E. , Ozkinay F. , Tezcan I. , Gedikoglu G. , Philippe N. , Fischer A. , de Saint Basile G.
Genomics63:299-306(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN GS1
19.

"Evidence that Griscelli syndrome with neurological involvement is caused by mutations in RAB27A, not MYO5A."
Anikster Y. , Huizing M. , Anderson P.D. , Fitzpatrick D.L. , Klar A. , Gross-Kieselstein E. , Berkun Y. , Shazberg G. , Gahl W.A. , Hurvitz H.
Am. J. Hum. Genet.71:407-414(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN ELEJAS
20.

Anikster Y. , Huizing M. , Anderson P.D. , Fitzpatrick D.L. , Klar A. , Gross-Kieselstein E. , Berkun Y. , Shazberg G. , Gahl W.A. , Hurvitz H.
Am. J. Hum. Genet.71:1007-1007(2002)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
21.

"Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1)."
Menasche G. , Ho C.H. , Sanal O. , Feldmann J. , Tezcan I. , Ersoy F. , Houdusse A. , Fischer A. , de Saint Basile G.
J. Clin. Invest.112:450-456(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN GS3

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