Gene name:
Myo5b (Kiaa1119) ;
Protein name:
Myosin-Vb ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3. Interacts with RAB11FIP2 (By similarity). Interacts with RAB11A and RAB8A (By similarity). Found in a complex with CFTR and RAB11A (By similarity). Interacts with NPC1L1.
Function:
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (By similarity). Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane (By similarity). Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells (By similarity). Together with RAB11A and RAB8A participates in epithelial cell polarization (By similarity). Together with RAB25 regulates transcytosis.
Subcellular Location:
N/A
Protein Attributes:
50:
MSYSELYTRY | TRVWIPDPDE | VWRSAELTKD | YKEGDKSLQL | RLEDDTILEY |
100:
PVDVQNNQVP | FLRNPDILVG | ENDLTALSHL | HEPAVLHNLK | VRFLESNHIY |
150:
TYCGIVLVAI | NPYEQLPIYG | QDVIYAYSGQ | NMGDMDPHIF | AVAEEAYKQM |
200:
ARDEKNQSII | VSGESGAGKT | VSAKYAMRYF | ATVGGSASDT | NIEEKVLASS |
250:
PIMEAIGNAK | TTRNDNSSRF | GKFIEIGFDK | KYHIIGANMR | TYLLEKSRVV |
300:
FQADDERNYH | IFYQLCAAAS | LPEFKELALT | CAEDFFYTAH | GGNTTIEGVN |
350:
DADDFEKTRQ | ALTLLGVRDS | HQISIFKIIA | SILHLGSVEI | QSERDGDSCS |
400:
ISPQDEHLSN | FCSLLGIEHS | QMEHWLCHRK | LVTTSETYVK | TMSLQQVVNA |
450:
RDALAKHIYA | QLFSWIVEHI | NKALHTSHKQ | HSFIGVLDIY | GFETFEINSF |
500:
EQFCINYANE | KLQQQFNSHV | FKLEQEEYMK | EQIPWTLIDF | YDNQPCIDLI |
550:
EAKLGILDLL | DEECKVPKGT | DQNWAQKLYE | RHSNSQHFQK | PRMSNTAFIV |
600:
NHFADKVEYL | SDGFLEKNRD | TVYEEQINIL | KASKFPLVAD | LFHDDKDSAP |
650:
ATNTAKNRSS | SKINVRSSRP | LIKVPNKEHK | KSVGYQFRTS | LNLLMETLNA |
700:
TTPHYVRCIK | PNDEKLPFHF | DPKRAVQQLR | ACGVLETIRI | SAAGYPSRWT |
750:
YHDFFNRYRV | LMKKRELTNT | DKKNICKSVL | ESLIKDPDKF | QFGRTKIFFR |
800:
AGQVAYLEKL | RADKFREATI | MIQKSVRGWL | QRVKYRRLRA | ATLSLQRFCR |
850:
GYLARRLAEH | LRRTRAAIVF | QKQYRMLKAR | RAYRRVCRAT | VIIQSFTRAM |
900:
FVRRNYRQVL | MEHKATIIQK | YARGWMARKR | FLRERDAAIV | IQCAFRRLKA |
950:
RQELKALKIE | ARSAEHLKRL | NVGMENKVVQ | LQRKIDDQNK | EFKTLSEQLS |
1000:
AVTSSHAVEV | EKLKKELAHY | QQNQEADTSL | QLQEEVQSLR | TELQKAHSER |
1050:
RVLEDAHNKE | NGELRKRVAD | LEHENALLKD | EKEYLNNQIL | CQSKAESSQS |
1100:
SVEENLLMKK | ELEEERSRYQ | NLVKEYSQLE | QRYENLRDEQ | TPGHRKNPSN |
1150:
QSSLESDSNY | PSISTSEIGD | TEDALQQVEE | IGIEKAAMDM | TVFLKLQKRV |
1200:
RELEQERKKL | QAQLEKGQQD | SKKGQVEQQN | NGLDVDQDAD | IAYNSLKRQE |
1250:
LESENKKLKN | DLNELRKAVA | DQAMQDNSTH | SSPDSYSLLL | NQLKLANEEL |
1300:
EVRKEEVLIL | RTQIMNADQR | RLSGKNMEPN | INARTSWPNS | EKHVDQEDAI |
1350:
EAYHGVCQTN | RLLEAQLQAQ | SLEHEEEVEH | LKAQVEALKE | EMDKQQQTFC |
1400:
QTLLLSPEAQ | VEFGVQQEIS | RLTNENLDFK | ELVEKLEKNE | RKLKKQLKIY |
1450:
MKKVQDLEAA | QALAQSDRRH | HELTRQVTVQ | RKEKDFQGML | EYHKEDEALL |
1500:
IRNLVTDLKP | QMLSGTVPCL | PAYILYMCIR | HADYTNDDLK | VHSLLSSTIN |
1550:
GIKKVLKKHN | DDFEMTSFWL | SNTCRFLHCL | KQYSGDEGFM | TQNTAKQNEH |
1600:
CLKNFDLTEY | RQVLSDLSIQ | IYQQLIKIAE | GLLQPMIVSA | MLENESIQGL |
1650:
SGVRPTGYRK | RSSSMVDGEN | SYCLEAIVRQ | MNSFHTVLCD | QGLDPEIILQ |
1700:
VFKQLFYMIN | AVTLNNLLLR | KDACSWSTGM | QLRYNISQLE | EWLRGKNLHQ |
1750:
SGAVQTMEPL | IQAAQLLQLK | KKTHEDAEAI | CSLCTSLSTQ | QIVKILNLYT |
1800:
PLNEFEERVT | VSFIRTIQAQ | LQERNDPQQL | LLDSKHVFPV | LFPYNPSALT |
1818:
MDSIHIPACL | NLEFLNEV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Mouse Myosin-Vb
ELISA Kit for Mouse Myosin-Vb
ELISA Kit for Mouse Myosin-Vb
CLIA Kit for Mouse Myosin-Vb
CLIA Kit for Mouse Myosin-Vb
CLIA Kit for Mouse Myosin-Vb
Polyclonal Antibody for Mouse Myosin-Vb
Polyclonal Antibody for Mouse Myosin-Vb
Polyclonal Antibody for Mouse Myosin-Vb
Monoclonal Antibody for Mouse Myosin-Vb
Monoclonal Antibody for Mouse Myosin-Vb
Monoclonal Antibody for Mouse Myosin-Vb
Protein for Mouse Myosin-Vb
Protein for Mouse Myosin-Vb
Protein for Mouse Myosin-Vb
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
FVB/N .
tissue :
Colon .
tissue :
Mammary tumor .
2.
"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N.
,
Kikuno R.
,
Ohara R.
,
Inamoto S.
,
Koseki H.
,
Hiraoka S.
,
Saga Y.
,
Seino S.
,
Nishimura M.
,
Kaisho T.
,
Hoshino K.
,
Kitamura H.
,
Nagase T.
,
Ohara O.
,
Koga H.
DNA Res.11:205-218(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1054-1818 (ISOFORM 3)
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1086-1818 (ISOFORM 1)
tissue :
Brain .