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Index > Protein center > MYO7A(Gene name) > Pig
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  • MYO7A (Gene name),
  • Myosin-VIIa (Protein name ),  MYO7A_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MYO7A;
    Protein name:
    Myosin-VIIa;
    Alternative:

    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Might homodimerize in a two headed molecule through the formation of a coiled-coil rod. Binds MYRIP and WHRN. Interacts with PLEKHB1 (via PH domain).
    Function:
    Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa might play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it might maintain the rigidity of stereocilia during the dynamic movements of the bundle. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    566
    Sequence:
    50:
    MVILQQGDYV | WMDLRSGQEF | DVPIGAVVKL | CDSGQIQVVD | DEGNEHWISP | 
    100:
    QNATHIKPMH | PTSVTGMMED | MIQHLGDLNE | AGILRNLLIR | YRDHLIYTYT | 
    150:
    GSILVAVNPY | QLLSIYSPEH | IRQYTNKKIG | EMPPHIFAIA | DNCYFNMKRN | 
    200:
    SRDQCCIISG | ESGAGKTEST | KLILQFLAAI | SGQHSWIEQQ | VLEATPILEA | 
    250:
    FGNAKTIRND | NSSRFGKYID | IHFNKRGAIE | GARIEQYLLE | KSRVCRQAPD | 
    300:
    ERNYHVFYCM | LEGMSEEQKK | KLGLGQATDY | NYLAMGNCIT | CEGREDSQEY | 
    350:
    ANIRSAMKVL | MFTDTENWEI | SKLLAAILHL | GNLQYKDRTF | ENLDACEVLF | 
    400:
    STALATAASL | LEVNPPDLMN | CLTSRTLITR | GETVSTPLSR | EQALDVRDAF | 
    450:
    VKGIYGRLFV | WIVDKINAAI | YKPPSQEVKN | PRRSIGLLDI | FGFENFAVNS | 
    500:
    FEQLCINFAN | EHLQQFFVRH | VFKLEQEEYD | LESIDWLHIE | FTDNQDALDM | 
    550:
    IANKPMNIIS | LIDEESKFPK | GTDTTMLHKL | NSQHRLNSNY | IPPKYNHETQ | 
    566:
    FGINHFAGVV | YYESQG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Pig Myosin-VIIa
    ELISA Kit for Pig Myosin-VIIa
    ELISA Kit for Pig Myosin-VIIa
    CLIA Kit for Pig Myosin-VIIa
    CLIA Kit for Pig Myosin-VIIa
    CLIA Kit for Pig Myosin-VIIa
    Polyclonal Antibody for Pig Myosin-VIIa
    Polyclonal Antibody for Pig Myosin-VIIa
    Polyclonal Antibody for Pig Myosin-VIIa
    Monoclonal Antibody for Pig Myosin-VIIa
    Monoclonal Antibody for Pig Myosin-VIIa
    Monoclonal Antibody for Pig Myosin-VIIa
    Protein for Pig Myosin-VIIa
    Protein for Pig Myosin-VIIa
    Protein for Pig Myosin-VIIa

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    References
    1. 1.
      "Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B."
      Hasson T. , Heintzelman M.B. , Santos-Sacchi J. , Corey D.P. , Mooseker M.S.
      Proc. Natl. Acad. Sci. U.S.A.92:9815-9819(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Kidney proximal tubule.
    2. 2.
      "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types."
      Bement W.M. , Hasson T. , Wirth J.A. , Cheney R.E. , Mooseker M.S.
      Proc. Natl. Acad. Sci. U.S.A.91:6549-6553(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 168-198
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
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