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Index > Protein center > MYOC(Gene name) > Bovine
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  • MYOC (Gene name),
  • Myocilin (Protein name ),  MYOC_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    MYOC(TIGR);
    Protein name:
    Myocilin;
    Alternative:
    Trabecular meshwork-induced glucocorticoid response protein;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with OLFM3.
    Function:
    May participate in the obstruction of fluid outflow in the trabecular meshwork.
    Subcellular Location:
    Rough endoplasmic reticulum Secreted Cell projection cilium Located preferentially in the ciliary rootlet and basal body of the connecting cilium of photoreceptor cells, and in the rough endoplasmic reticulum. Also secreted.
    Protein Attributes:
    Sequence length:
    490
    Sequence:
    50:
    MPAVQLLLLA | CLLGGVGART | AQFQKANDRS | GRCQYTFSVA | SPSESSCPEQ | 
    100:
    GQAMLAIQEL | QRDSSEQRAT | LESTKARLSS | LEALLHRLTS | GQPAGPLETH | 
    150:
    QGLQRELEAL | RREREQLETQ | TQELESAYSN | LVRDKSALEE | EKRRLQAENE | 
    200:
    DLARRLESSS | QEVASLRRGQ | CPQAHSSSQD | VPSGSREVAK | WNLENMDFQE | 
    250:
    LKSELTEVPA | SQILKESPSG | HPRNEEGGTG | CGELVWVGEP | ITLRTAETIT | 
    300:
    GKYGVWMRDP | RAAFPYTGET | TWRIDTVGTD | IRQVFEYDHI | RKFTQGYPSK | 
    350:
    VHVLPRPLES | TGAVVYRGSL | YFQAAESRTV | LRYDLRTETL | KAEKEIPGAG | 
    400:
    YHGQFPYSWG | GYTDIDLAVD | EIGLWVIYST | EAAKGAIVLS | KLNPETLELE | 
    450:
    QTWETNIRKQ | SVANAFIICG | TLYTVSSYSS | PDATVNFAYD | TGTGSSKALT | 
    490:
    VPFKNRYKYS | SMIDYNPLER | KLFAWDNFNM | VSYDIKLSRL | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Myocilin
    ELISA Kit for Bovine Myocilin
    ELISA Kit for Bovine Myocilin
    ELISA Kit for Bovine Myocilin
    ELISA Kit for Bovine Myocilin
    ELISA Kit for Bovine Myocilin
    CLIA Kit for Bovine Myocilin
    CLIA Kit for Bovine Myocilin
    CLIA Kit for Bovine Myocilin
    CLIA Kit for Bovine Myocilin
    CLIA Kit for Bovine Myocilin
    CLIA Kit for Bovine Myocilin
    Polyclonal Antibody for Bovine Myocilin
    Polyclonal Antibody for Bovine Myocilin
    Polyclonal Antibody for Bovine Myocilin
    Polyclonal Antibody for Bovine Myocilin
    Polyclonal Antibody for Bovine Myocilin
    Polyclonal Antibody for Bovine Myocilin
    Monoclonal Antibody for Bovine Myocilin
    Monoclonal Antibody for Bovine Myocilin
    Monoclonal Antibody for Bovine Myocilin
    Monoclonal Antibody for Bovine Myocilin
    Monoclonal Antibody for Bovine Myocilin
    Monoclonal Antibody for Bovine Myocilin
    Protein for Bovine Myocilin
    Protein for Bovine Myocilin
    Protein for Bovine Myocilin
    Protein for Bovine Myocilin
    Protein for Bovine Myocilin
    Protein for Bovine Myocilin

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    References
    1. 1.
      "Molecular cloning of the bovine MYOC and induction of its expression in trabecular meshwork cells."
      Taniguchi F. , Suzuki Y. , Kurihara H. , Kurihara Y. , Kasai H. , Shirato S. , Araie M.
      Invest. Ophthalmol. Vis. Sci.41:2070-2075(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Trabecular meshwork.
    2. 2.
      "Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227."
      Aroca-Aguilar J.D. , Sanchez-Sanchez F. , Ghosh S. , Coca-Prados M. , Escribano J.
      J. Biol. Chem.280:21043-21051(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;SUBCELLULAR LOCATION
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