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Index > Protein center > Myog(Gene name) > Mouse
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  • Myog (Gene name),
  • Myogenin (Protein name ),  MYOG_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Myog;
    Protein name:
    Myogenin;
    Alternative:
    MYOD1-related protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Efficient DNA binding requires dimerization with another bHLH protein.
    Function:
    Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    224
    Sequence:
    50:
    MELYETSPYF | YQEPHFYDGE | NYLPVHLQGF | EPPGYERTEL | SLSPEARGPL | 
    100:
    EEKGLGTPEH | CPGQCLPWAC | KVCKRKSVSV | DRRRAATLRE | KRRLKKVNEA | 
    150:
    FEALKRSTLL | NPNQRLPKVE | ILRSAIQYIE | RLQALLSSLN | QEERDLRYRG | 
    200:
    GGGPQPMVPS | ECNSHSASCS | PEWGNALEFG | PNPGDHLLAA | DPTDAHNLHS | 
    224:
    LTSIVDSITV | EDMSVAFPDE | TMPN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Myogenin
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    E1109h
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    ELISA Kit for Mouse Myogenin
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    E1109m
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    ELISA Kit for Mouse Myogenin
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    E1109r
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    ELISA Kit for Mouse Myogenin
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    E1109b
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    ELISA Kit for Mouse Myogenin
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    E1109c
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    ELISA Kit for Mouse Myogenin
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    E1109p
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    CLIA Kit for Mouse Myogenin
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    U1109p
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    CLIA Kit for Mouse Myogenin
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    U1109m
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    CLIA Kit for Mouse Myogenin
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    U1109b
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    CLIA Kit for Mouse Myogenin
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    U1109h
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    CLIA Kit for Mouse Myogenin
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    U1109c
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    CLIA Kit for Mouse Myogenin
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    U1109r
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Myogenin
    Polyclonal Antibody for Mouse Myogenin
    Cat.:
    P1109Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Myogenin
    Polyclonal Antibody for Mouse Myogenin
    Polyclonal Antibody for Mouse Myogenin
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    P1109Rb-r
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    Packing:
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    Polyclonal Antibody for Mouse Myogenin
    Cat.:
    P1109Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Myogenin
    Monoclonal Antibody for Mouse Myogenin
    Monoclonal Antibody for Mouse Myogenin
    Monoclonal Antibody for Mouse Myogenin
    Monoclonal Antibody for Mouse Myogenin
    Monoclonal Antibody for Mouse Myogenin
    Protein for Mouse Myogenin
    Protein for Mouse Myogenin
    Protein for Mouse Myogenin
    Protein for Mouse Myogenin
    Protein for Mouse Myogenin
    Protein for Mouse Myogenin

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    References
    1. 1.
      "A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program."
      Edmondson D.G. , Olson E.N.
      Genes Dev.3:628-640(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Muscle.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    3. 3.
      "Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2."
      Edmondson D.G. , Cheng T.C. , Cserjesi P. , Chakraborty T. , Olson E.N.
      Mol. Cell. Biol.12:3665-3677(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Myogenin contains two domains conserved among myogenic factors."
      Fujisawa-Sehara A. , Nabeshima Y. , Hosoda Y. , Obinata T. , Nabeshima Y.
      J. Biol. Chem.265:15219-15223(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Limb.
    6. 6.
      "Expression of two myogenic regulatory factors myogenin and MyoD1 during mouse embryogenesis."
      Sassoon D. , Lyons G. , Wright W.E. , Lin V. , Lassar A. , Weintraub H. , Buckingham M.
      Nature341:303-307(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    7. 7.
      "Myogenin and MyoD join a family of skeletal muscle genes regulated by electrical activity."
      Eftimie R. , Brenner H.R. , Buonanno A.
      Proc. Natl. Acad. Sci. U.S.A.88:1349-1353(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    8. 8.
      "Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene."
      Hasty P. , Bradley A. , Morris J.H. , Edmondson D.G. , Venuti J.M. , Olson E.N. , Klein W.H.
      Nature364:501-506(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    9. 9.
      "Myogenin gene disruption results in perinatal lethality because of severe muscle defect."
      Nabeshima Y. , Hanaoka K. , Hayasaka M. , Esumi E. , Li S. , Nonaka I. , Nabeshima Y.
      Nature364:532-535(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    10. 10.
      "Somite subdomains, muscle cell origins, and the four muscle regulatory factor proteins."
      Smith T.H. , Kachinsky A.M. , Miller J.B.
      J. Cell Biol.127:95-105(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    11. 11.
      "Analysis of the DNA-binding properties of MyoD, myogenin, and E12 by fluorescence anisotropy."
      Maleki S.J. , Royer C.A. , Hurlburt B.K.
      Biochemistry41:10888-10894(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PROMOTER BINDING
    13. 13.
      "Loss of myogenin in postnatal life leads to normal skeletal muscle but reduced body size."
      Knapp J.R. , Davie J.K. , Myer A. , Meadows E. , Olson E.N. , Klein W.H.
      Development133:601-610(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CONDITIONAL KNOCKOUT IN MUSCLE CELLS
    14. 14.
      "Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1."
      Ohkawa Y. , Marfella C.G. , Imbalzano A.N.
      EMBO J.25:490-501(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SMARCA4;SUBCELLULAR LOCATION
    15. 15.
      "Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters."
      Cao Y. , Kumar R.M. , Penn B.H. , Berkes C.A. , Kooperberg C. , Boyer L.A. , Young R.A. , Tapscott S.J.
      EMBO J.25:502-511(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    16. 16.
      "Myogenin regulates denervation-dependent muscle atrophy in mouse soleus muscle."
      Macpherson P.C. , Wang X. , Goldman D.
      J. Cell. Biochem.112:2149-2159(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CONDITIONAL KNOCKOUT IN MUSCLE CELLS;INDUCTION;TISSUE SPECIFICITY
    17. 17.
      "Sequential association of myogenic regulatory factors and E proteins at muscle-specific genes."
      Londhe P. , Davie J.K.
      Skelet. Muscle1:14-14(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PROMOTER BINDING;INDUCTION;TISSUE SPECIFICITY
    18. 18.
      "Comparative expression profiling identifies differential roles for Myogenin and p38alpha MAPK signaling in myogenesis."
      Liu Q.C. , Zha X.H. , Faralli H. , Yin H. , Louis-Jeune C. , Perdiguero E. , Pranckeviciene E. , Munoz-Canoves P. , Rudnicki M.A. , Brand M. , Perez-Iratxeta C. , Dilworth F.J.
      J. Mol. Cell Biol.4:386-397(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
    19. 19.
      "Down-regulation of myogenin can reverse terminal muscle cell differentiation."
      Mastroyiannopoulos N.P. , Nicolaou P. , Anayasa M. , Uney J.B. , Phylactou L.A.
      PLoS ONE7:E29896-E29896(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN MUSCLE DEDIFFERENTIATION INHIBITION
    20. 20.
      "Myogenin recruits the histone chaperone facilitates chromatin transcription (FACT) to promote nucleosome disassembly at muscle-specific genes."
      Lolis A.A. , Londhe P. , Beggs B.C. , Byrum S.D. , Tackett A.J. , Davie J.K.
      J. Biol. Chem.288:7676-7687(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SSRP1 AND SUPT16H
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