Protein name:
Myopalladin ;
Alternative:
145 kDa sarcomeric protein ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with TTN/titin, NEB, NEBL, ACTN2 and CARP.
Function:
Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines.
Subcellular Location:
Cytoplasm
Nucleus
Cytoplasm
myofibril
sarcomere
Bound to sarcomere both at the Z-line periphery and in the central I-band region.
Protein Attributes:
50:
MQDDSIEAST | SISQLLRESY | LAETRHRGNN | ERSRAEPSSN | PCHFGSPSGA |
100:
AEGGGGQDDL | PDLSAFLSQE | ELDESVNLAR | LAINYDPLEK | ADETQARKRL |
150:
SPDQMKHSPN | LSFEPNFCQD | NPRSPTSSKE | SPQEAKRPQY | CSETQSKKVF |
200:
LNKAADFIEE | LSSLFKSHSS | KRIRPRACKN | HKSKLESQNK | VMQENSSSFS |
250:
DLSERRERSS | VPIPIPADTR | DNEVNHALEQ | QEAKRREAEQ | AASEAAGGDT |
300:
TPGSSPSSLY | YEEPLGQPPR | FTQKLRSREV | PEGTRVQLDC | IVVGIPPPQV |
350:
RWYCEGKELE | NSPDIHIVQA | GNLHSLTIAE | AFEEDTGRYS | CFASNIYGTD |
400:
STSAEIYIEG | VSSSDSEGDP | NKEEMNRIQK | PNEVSSPPTT | SAVIPPAVPQ |
450:
AQHLVAQPRV | ATIQQCQSPT | NYLQGLDGKP | IIAAPVFTKM | LQNLSASEGQ |
500:
LVVFECRVKG | APSPKVEWYR | EGTLIEDSPD | FRILQKKPRS | MAEPEEICTL |
550:
VIAEVFAEDS | GCFTCTASNK | YGTVSSIAQL | HVRGNEDLSN | NGSLHSANST |
600:
TNLAAIEPQP | SPPHSEPPSV | EQPPKPKLEG | VLVNHNEPRS | SSRIGLRVHF |
650:
NLPEDDKGSE | ASSEAGVVTT | RQTRPDSFQE | RFNGQATKTP | EPSSPVKEPP |
700:
PVLAKPKLDS | TQLQQLHNQV | LLEQHQLQNP | PPSSPKEFPF | SMTVLNSNAP |
750:
PAVTTSSKQV | KAPSSQTFSL | ARPKYFFPST | NTTAATVAPS | SSPVFTLSST |
800:
PQTIQRTVSK | ESLLVSHPSV | QTKSPGGLSI | QNEPLPPGPT | EPTPPPFTFS |
850:
IPSGNQFQPR | CVSPIPVSPT | SRIQNPVAFL | SSVLPSLPAI | PPTNAMGLPR |
900:
SAPSMPSQGL | AKKNTKSPQP | VNDDNIRETK | NAVIRDLGKK | ITFSDVRPNQ |
950:
QEYKISSFEQ | RLMNEIEFRL | ERTPVDESDD | EIQHDEIPTG | KCIAPIFDKR |
1000:
LKHFRVTEGS | PVTFTCKIVG | IPVPKVYWFK | DGKQISKRNE | HCKMRREGDG |
1050:
TCSLHIESTT | SDDDGNYTIM | AANPQGRISC | SGHLMVQSLP | IRSRLTSAGQ |
1100:
SHRGRSRVQE | RDKEPLQERF | FRPHFLQAPG | DMVAHEGRLC | RLDCKVSGLP |
1150:
PPELTWLLNG | QPVLPDASHK | MLVRETGVHS | LLIDPLTQRD | AGTYKCIATN |
1200:
KTGQNSFSLE | LSVVAKEVKK | APVILEKLQN | CGVPEGHPVR | LECRVIGMPP |
1250:
PVFYWKKDNE | TIPCTRERIS | MHQDTTGYAC | LLIQPAKKSD | AGWYTLSAKN |
1300:
EAGIVSCTAR | LDIYAQWHHQ | IPPPMSVRPS | GSRYGSLTSK | GLDIFSAFSS |
1320:
MESTMVYSCS | SRSVVESDEL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Myopalladin
ELISA Kit for Human Myopalladin
CLIA Kit for Human Myopalladin
CLIA Kit for Human Myopalladin
Polyclonal Antibody for Human Myopalladin
Polyclonal Antibody for Human Myopalladin
Monoclonal Antibody for Human Myopalladin
Monoclonal Antibody for Human Myopalladin
Protein for Human Myopalladin
Protein for Human Myopalladin
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
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PubMed ]
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH NEB; NEBL; ACTN2 AND CARP;VARIANTS ASN-691; ASN-707 AND ARG-803
tissue :
Skeletal muscle .
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue :
Embryo .
3.
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BMC Genomics8:399-399(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Skeletal muscle .
4.
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Nature429:375-381(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TTN
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-928;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-251; SER-759; SER-813; SER-818 AND SER-928;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
8.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
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Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-101; SER-813 AND SER-928;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.
"Molecular basis for clinical heterogeneity in inherited cardiomyopathies due to myopalladin mutations."
Purevjav E.
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Machida N.
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Park J.E.
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Kimura A.
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more...
Hum. Mol. Genet.21:2039-2053(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN RCM4;VARIANTS CHM22 CYS-20; ARG-153; GLU-217; ALA-410; THR-841; LEU-1112; ILE-1161 AND PRO-1265;VARIANTS CMD1KK CYS-20; VAL-213; PHE-339; THR-611; THR-882 AND LEU-954;VARIANTS ALA-393; LYS-467; LYS-614; LEU-628; ASN-691; ASN-707; ARG-803; ARG-804; GLN-955; THR-1135 AND GLY-1306;CHARACTERIZATION OF VARIANT CHM22 CYS-20
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS CMD1KK HIS-1088; LEU-1112 AND MET-1195;CHARACTERIZATION OF VARIANTS CMD1KK LEU-1112 AND MET-1195
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS CMD1KK TRP-955 AND LEU-961;VARIANTS ALA-393; LEU-628; ASN-691; ASN-707; ARG-803 AND THR-1135