Myzap ELISA Kit for Rat(Rattus norvegicus) | EIAab.comMyzap ELISA Kit for Rat(Rattus norvegicus)

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Myzap (Gene name),

Myocardial zonula adherens protein (Protein name ), MYZAP_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Myzap(Myozap);

Protein name:

Myocardial zonula adherens protein;

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with DSP, MPRIP and TJP1/ZO1. Interaction with MPRIP inhibits the activation of transcription factor SRF (By similarity). Interacts with GRIN1. Interacts with DYNLL1.

Function:

Plays a role in cellular signaling via Rho-related GTP-binding proteins and activation of transcription factor SRF. Targets TJP1 to cell junctions (By similarity). In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1.

Subcellular Location:

Cytoplasm Cytoskeleton Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm Myofibril Sarcomere I band Cytoplasm Myofibril Sarcomere Z line Cell junction Detected predominantly at the intercalated disk in cardiomyocytes, and at low levels on sarcomeric Z disKs. Colocalizes with F-actin. Colocalizes with cortical actin. In neurons, colocalizes with GRIN1 in postsynaptic neurites.

Protein Attributes:

Sequence length:

466

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

466:

TPYTRVLELT | SKKTLT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:363091

UniGene:

Rn.2307

Uniprot:

Q5EB94

FOR

ELISA Kit for Rat Myocardial zonula adherens protein

CLIA Kit for Rat Myocardial zonula adherens protein

Polyclonal Antibody for Rat Myocardial zonula adherens protein

Monoclonal Antibody for Rat Myocardial zonula adherens protein

Protein for Rat Myocardial zonula adherens protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Thymus.
2.

"GRINL1A colocalizes with N-methyl D-aspartate receptor NR1 subunit and reduces N-methyl D-aspartate toxicity."
Roginski R.S. , Goubaeva F. , Mikami M. , Fried-Cassorla E. , Nair M.R. , Yang J.
NeuroReport19:1721-1726(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH GRIN1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
3.

"Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo."
Seeger T.S. , Frank D. , Rohr C. , Will R. , Just S. , Grund C. , Lyon R. , Luedde M. , Koegl M. , Sheikh F. , Rottbauer W. , Franke W.W. , Katus H.A. , Olson E.N. , Frey N.
Circ. Res.106:880-890(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY

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