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Index > Protein center > NASP(Gene name) > Rabbit
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  • NASP (Gene name),
  • Nuclear autoantigenic sperm protein (Protein name ),  NASP_RABIT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    NASP;
    Protein name:
    Nuclear autoantigenic sperm protein(NASP);
    Alternative:

    Organism:
    Rabbit (Oryctolagus cuniculus). 
    General Annotation
    Sub Unit:
    Binds to linker H1 histones but not to core histones. Also binds to HSP90 in the cytoplasm. This interaction stimulates binding of NASP to HIST1H1T/H1T.
    Function:
    Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.
    Subcellular Location:
    Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    693
    Sequence:
    50:
    IYYTFDSFFC | SPRMENGVLG | NALEGVHVEE | EEGEKTEEES | LVENNDNVDE | 
    100:
    EAREELREQV | YDAMGEKEES | KKTEGMSLSK | PETAKEQESE | MEKGGREDMD | 
    150:
    ISEPTEELPE | KVALTPDQLT | ETSEEAEGAA | APEGLNEAEV | TSGKSEQEAA | 
    200:
    DAEKGKSVSG | TDVQEEHKEQ | VEEKQGEVIV | RIEKPTEASE | EQPGTTLGKD | 
    250:
    NTAVEVEAEP | VDATAKPVDV | GGHEPKEQMA | TSGNEPGKAV | LNQQLVGQDV | 
    300:
    PPVEESPMVT | TEAAEVGSEV | SEKSEQEATV | VSNDGAVNGL | SAAGDQASVD | 
    350:
    PQPSAERVTE | TKGGSELEEV | RAELAPSQEA | KLPIEESEGA | GDGVETKVAQ | 
    400:
    GVTEKSPEDK | VKIAANEETQ | EREEQMKEGE | ETEGSEEEDK | ENDKAEEETP | 
    450:
    NDSVLENKSL | PENEEEEIGN | LELAWDMLDL | AKIIFKRQET | KEAQLYAAQA | 
    500:
    HLKLGEVSVE | SQNYIQAVEE | FQACLSLQEQ | YLEAHDRLLA | ETHYQLGLAY | 
    550:
    GYNSQYDEAV | AQFSKSIEVI | EKRMAVLNEQ | MKEAEGSSTE | YEKEIEELKE | 
    600:
    LLPEIREKIE | DAKESQRSGN | VAELALKATL | VGSSTSGFTP | SGGGSSVSTI | 
    650:
    ASRKPADGAS | SSNCVTDISH | LVRKKRKPEE | ESPRKDDAKK | AKQEPEVNGG | 
    693:
    SGDAVPSGNE | VSENMEEAEN | QTESRAAMEG | TVEAGATVES | TAC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rabbit NASP
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    CLIA Kit for Rabbit NASP
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    Monoclonal Antibody for Rabbit NASP
    Monoclonal Antibody for Rabbit NASP
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    Monoclonal Antibody for Rabbit NASP
    Monoclonal Antibody for Rabbit NASP
    Protein for Rabbit NASP
    Protein for Rabbit NASP
    Protein for Rabbit NASP
    Protein for Rabbit NASP
    Protein for Rabbit NASP

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    References
    1. 1.
      "Characterization of a sperm-specific nuclear autoantigenic protein. I. Complete sequence and homology with the Xenopus protein, N1/N2."
      Welch J.E. , Zimmerman L.J. , Joseph D.R. , O'Rand M.G.
      Biol. Reprod.43:559-568(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: New Zealand white.
      tissue: Testis.
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