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Index > Protein center > Nat8l(Gene name) > Mouse
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  • Nat8l (Gene name),
  • N-acetylaspartate synthetase (Protein name ),  NAT8L_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Nat8l;
    Protein name:
    N-acetylaspartate synthetase(NAA synthetase);
    Alternative:
    Protein Shati;N-acetyltransferase 8-like protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.
    Subcellular Location:
    Cytoplasm Membrane Single-pass membrane protein Microsome membrane Single-pass membrane protein Mitochondrion membrane Single-pass membrane protein Rough endoplasmic reticulum membrane Single-pass membrane protein
    Protein Attributes:
    Sequence length:
    299
    Sequence:
    50:
    MHCGPPDMVC | ETKIVATEDH | EALPGAKKDA | LLVAAGAMWP | PLPAAPGPAA | 
    100:
    APPPAAGPQP | HGGTGGAGPP | EGRGVCIREF | RAAEQEAARR | IFYDGILERI | 
    150:
    PNTAFRGLRQ | HPRTQLLYAL | LAALCFAVTR | SLLLTCLVPA | GLLALRYYYS | 
    200:
    RKVILAYLEC | ALHTDMADIE | QYYMKPPGSC | FWVAVLDGNV | VGIVAARAHE | 
    250:
    EDNTVELLRM | SVDSRFRGKS | IAKALGRRVL | EFAMLHNYSA | VVLGTTAVKV | 
    299:
    AAHKLYESLG | FRHMGASDHY | VLPGMTLSLA | ERLFFQVRYH | RYRLQLREE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse NAA synthetase
    Cat.:
    E4070r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse NAA synthetase
    Cat.:
    E4070h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse NAA synthetase
    Cat.:
    E4070m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse NAA synthetase
    Cat.:
    U4070r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse NAA synthetase
    Cat.:
    U4070m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse NAA synthetase
    Cat.:
    U4070h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse NAA synthetase
    Cat.:
    P4070Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse NAA synthetase
    Cat.:
    P4070Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse NAA synthetase
    Monoclonal Antibody for Mouse NAA synthetase
    Monoclonal Antibody for Mouse NAA synthetase
    Monoclonal Antibody for Mouse NAA synthetase
    Protein for Mouse NAA synthetase
    Protein for Mouse NAA synthetase
    Protein for Mouse NAA synthetase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      strain: C57BL/6J.
      tissue: Brain.
    2. 2.
      "A novel molecule 'Shati' is involved in methamphetamine-induced hyperlocomotion, sensitization, and conditioned place preference."
      Niwa M. , Nitta A. , Mizoguchi H. , Ito Y. , Noda Y. , Nagai T. , Nabeshima T.
      J. Neurosci.27:7604-7615(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 21-299;IDENTIFICATION;TISSUE SPECIFICITY;INDUCTION BY METHAMPHETAMINE
      strain: C57BL/6J.
      tissue: Brain.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 21-299
      strain: C57BL/6.
      strain: FVB/N.
      tissue: Brain.
      tissue: Colon.
    4. 4.
      "A novel molecule 'shati' increases dopamine uptake via the induction of tumor necrosis factor-alpha in pheochromocytoma-12 cells."
      Niwa M. , Nitta A. , Cen X. , Kitaichi K. , Ozaki N. , Yamada K. , Nabeshima T.
      J. Neurochem.107:1697-1708(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia."
      Wiame E. , Tyteca D. , Pierrot N. , Collard F. , Amyere M. , Noel G. , Desmedt J. , Nassogne M.C. , Vikkula M. , Octave J.N. , Vincent M.F. , Courtoy P.J. , Boltshauser E. , van Schaftingen E.
      Biochem. J.425:127-136(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    6. 6.
      "Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: implications for specialized acetyl coenzyme A metabolism in the CNS."
      Ariyannur P.S. , Moffett J.R. , Manickam P. , Pattabiraman N. , Arun P. , Nitta A. , Nabeshima T. , Madhavarao C.N. , Namboodiri A.M.
      Brain Res.1335:1-13(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    7. 7.
      "Molecular characterization of N-acetylaspartylglutamate synthetase."
      Becker I. , Lodder J. , Gieselmann V. , Eckhardt M.
      J. Biol. Chem.285:29156-29164(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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