Protein name:
Next to BRCA1 gene 1 protein ;
Alternative:
Neighbor of BRCA1 gene 1 protein ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homooligomer and heterooligomer. Interacts with RNF29, USP8, SQSTM1, MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2 (By similarity). Binds to ubiquitin and ubiquitinated proteins (By similarity). Interacts with SQSTM1, titin/TTN and TRIM55.
Function:
Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.
Subcellular Location:
Cytoplasm
Cytoplasmic vesicle
autophagosome
Lysosome
Cytoplasm
myofibril
sarcomere
M line
In cardiac muscles localizes to the sarcomeric M line (By similarity). Is targeted to lysosomes for degradation.
Protein Attributes:
50:
MEPQVTLNVT | FKNETQSFLV | SDPENTTWAD | VEAMVKVSFD | LNTIQIKYLD |
100:
EENEEISINS | QGEYEEALKM | ANIKQGNQLQ | MQVHEGCHVV | DEVLPQTVVE |
150:
KQATARTGKK | PLAHYSSLVR | VLGSDMKTTE | EPTAEARSPV | PCDTDKPQDK |
200:
PPDWFTSYLE | MFREQVVKET | VEKLEQRLQE | KLVLQKPPFS | SSPSEVSMPI |
250:
SEEETLFLPE | NQFSWHIACS | HCQKRIVGVR | YQCSLCPSYN | ICEDCEAGPY |
300:
SHDTNHILLK | FRRPVVISSE | PFFYSKYPTP | RLPAALEQVR | LQKQVDKNFV |
350:
KAEKQRLRAE | KKQRKAEVKE | LKKQLKLHRK | IHLWNSIHGL | QSPKSPLGRP |
400:
ESLLQSNTLM | LPLQPCAPVM | PTLSAAFVDE | NLPDGTHLQP | GTKFIKHWRM |
450:
KNTGNVKWSA | DTKLKFMWGN | LTLASTEKKD | VLVPCLKAGH | IGVVSVEFIA |
500:
PTLEGTYTLH | WRLSHKGQQF | GPRVWCSIIV | DPFPSSESPV | NLERDGISSS |
550:
KADDFTCEQE | EAFLLAEEEI | PLGEVTKQTE | GTGSSAPQKT | QHAASERELY |
600:
IPSVDLLTAQ | DLLSFELLDI | NIVQELERVP | HNTPVDVTPR | MSPLPHDSPL |
650:
IEKPGLGRIQ | EESEGAGLKA | SPDSTVLTKR | KAETPASVEE | TEEDLSGTQF |
700:
VCETVIRSLT | LDAAPDHNPP | CRQRSPQREL | QLYSTEEQQP | LMLPGFCRKD |
750:
SSLKFALPEE | GPHGDEREEI | VHIAEEEAIE | EEDVQDEEVQ | SQSSASSEDY |
800:
IIILPECFDT | SRPLGDSMYS | SALSQPGLER | GAEGEPGIES | GQEPAEARER |
850:
LPERESQPKE | QSISDILTTS | QHLDTVPLVP | EVAGLPAALS | RSAPCGQYEA |
900:
PRVDSPVTIQ | EVLPVPDHVR | GEPRGSTGLA | NSRQKSCDHS | RHHNGSSIAG |
950:
GLVKGALSVA | ASAYKALFSG | PPVTAQPVIS | EDQTAALMAH | LFEMGFCDRQ |
983:
LNLRLLRKHN | HNILQVVTEL | LQVNNNDWYS | HRY
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat Next to BRCA1 gene 1 protein
ELISA Kit for Rat Next to BRCA1 gene 1 protein
ELISA Kit for Rat Next to BRCA1 gene 1 protein
CLIA Kit for Rat Next to BRCA1 gene 1 protein
CLIA Kit for Rat Next to BRCA1 gene 1 protein
CLIA Kit for Rat Next to BRCA1 gene 1 protein
Polyclonal Antibody for Rat Next to BRCA1 gene 1 protein
Polyclonal Antibody for Rat Next to BRCA1 gene 1 protein
Polyclonal Antibody for Rat Next to BRCA1 gene 1 protein
Monoclonal Antibody for Rat Next to BRCA1 gene 1 protein
Monoclonal Antibody for Rat Next to BRCA1 gene 1 protein
Monoclonal Antibody for Rat Next to BRCA1 gene 1 protein
Protein for Rat Next to BRCA1 gene 1 protein
Protein for Rat Next to BRCA1 gene 1 protein
Protein for Rat Next to BRCA1 gene 1 protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Lung .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-43
strain :
SHR .
tissue :
Testis .
3.
"The kinase domain of titin controls muscle gene expression and protein turnover."
Lange S.
,
Xiang F.
,
Yakovenko A.
,
Vihola A.
,
Hackman P.
,
Rostkova E.
,
Kristensen J.
,
Brandmeier B.
,
Franzen G.
,
Hedberg B.
,
Gunnarsson L.G.
,
Hughes S.M.
,
Marchand S.
,
Sejersen T.
,
Richard I.
,
Edstroem L.
,
Ehler E.
,
Udd B.
,
Gautel M.
more...
Science308:1599-1603(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SQSTM1; TTN AND TRIM55;SUBCELLULAR LOCATION