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Index > Protein center > Slc24a1(Gene name) > Rat
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  • Slc24a1 (Gene name),
  • Sodium/potassium/calcium exchanger 1 (Protein name ),  NCKX1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc24a1(Nckx1);
    Protein name:
    Sodium/potassium/calcium exchanger 1;
    Alternative:
    Retinal rod Na-Ca+K exchanger;Na(+)/K(+)/Ca(2+)-exchange protein 1;Solute carrier family 24 member 1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1181
    Sequence:
    50:
    MGKLIRMGTQ | ERRLLRPKRL | HWSRLLFFLG | MLIIGSTYQH | LRRPQNPPSM | 
    100:
    WTKVSSQQPI | KLAIRDLPND | EITVTDKDPP | EASSEVEGEM | LAPQDTVIIG | 
    150:
    EAAPSIAMED | TPNPPITTKI | TPTSLKNNYS | PTTAGTRRQK | ENIPPTPSRA | 
    200:
    PSHFISTSGR | QRVKSYTPKP | RGGRKSSSPT | HTREEGRMHT | PSPAGAPRTI | 
    250:
    SPTSTEKDSE | TTATYRMLEP | RSERTAGKTS | LKRMVPNTRT | FLTREVETDL | 
    300:
    VTSPSLVGKN | TLGSPRRGER | NSSTTPLRAV | LQPTPATSEE | QVTASIRMGS | 
    350:
    TPATTEGSTA | AQRIGNPLSG | TSTPAVRIAS | VTDREKRPST | AHGTLVTPQV | 
    400:
    KAVLTTQVHR | CVVVKPAPAV | PMTPSPSMTA | ILFPEAPTSG | PSALPPGWPN | 
    450:
    LHPKAEYPPD | LFSVEDRRQG | WVVLHIFGMT | YVFVALAIVC | DEYFVPALGV | 
    500:
    ITDKLQISED | VAGATFMAAG | GSAPELFTSL | IGVFISHSNV | GIGTIVGSAV | 
    550:
    FNILFVIGTC | ALFSREILNL | TWWPLFRDVS | FYILDLSMLI | VFFLDSLIAW | 
    600:
    WESLLLLLAY | ALYVFTMKWN | KQIERWVKEQ | LSRRPVAKVM | ALGDLSKPSD | 
    650:
    GAIEENEQQD | NKKLKLPSVL | TRGSSSASLH | NSIIRSTIYH | LMLHSLDPLG | 
    700:
    EARPSKDKQE | SLNQEARVLP | QTKAESSSDE | EEPAELPAVT | VTPAPAPEDK | 
    750:
    GDQEEDPGCQ | EDVDEAEHRG | DMTGEEGERE | TEAEGKKDEE | GETEAERKED | 
    800:
    GQEEETETKG | KEKQEGETES | EGKDEQEGET | EAEGKEADHE | GETEAEGKEV | 
    850:
    EHEGETEAEG | TEDEQEGETE | AEGKEVEQEG | ETEAEGKEVE | HEVETEAERK | 
    900:
    ETNHEGETEA | EGKEADHEGE | TEAEGNVEHQ | GETEAEGKVE | HEGETEAGEK | 
    950:
    DEHEGQSETQ | ADDTEVKDGE | GEAEANAEDQ | CETAQGEKGA | DGGGGSDGGD | 
    1000:
    SEEEEDEEDE | EEEEEEEEEE | EEEESEEPLS | LEWPESRQKQ | AIYLFLLPIV | 
    1050:
    FPLWLTIPDV | RRQEARKFFV | ITFLGSIIWI | AMFSYLMVWW | AHQVGETIGI | 
    1100:
    SEEIMGLTIL | AAGTSIPDLI | TSVIVARKGL | GDMAVSSSVG | SNIFDITVGL | 
    1150:
    PVPWLLFSLI | NALQPIPVSS | NGLFCAIVLL | FLMLLFVIFS | IASCKWRMNK | 
    1181:
    ILGFTMFLLY | FVFLVISVML | EDRIISCPVS | V
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Sodium/potassium/calcium exchanger 1
    ELISA Kit for Rat Sodium/potassium/calcium exchanger 1
    ELISA Kit for Rat Sodium/potassium/calcium exchanger 1
    ELISA Kit for Rat Sodium/potassium/calcium exchanger 1
    CLIA Kit for Rat Sodium/potassium/calcium exchanger 1
    CLIA Kit for Rat Sodium/potassium/calcium exchanger 1
    CLIA Kit for Rat Sodium/potassium/calcium exchanger 1
    CLIA Kit for Rat Sodium/potassium/calcium exchanger 1
    Polyclonal Antibody for Rat Sodium/potassium/calcium exchanger 1
    Polyclonal Antibody for Rat Sodium/potassium/calcium exchanger 1
    Polyclonal Antibody for Rat Sodium/potassium/calcium exchanger 1
    Polyclonal Antibody for Rat Sodium/potassium/calcium exchanger 1
    Monoclonal Antibody for Rat Sodium/potassium/calcium exchanger 1
    Monoclonal Antibody for Rat Sodium/potassium/calcium exchanger 1
    Monoclonal Antibody for Rat Sodium/potassium/calcium exchanger 1
    Monoclonal Antibody for Rat Sodium/potassium/calcium exchanger 1
    Protein for Rat Sodium/potassium/calcium exchanger 1
    Protein for Rat Sodium/potassium/calcium exchanger 1
    Protein for Rat Sodium/potassium/calcium exchanger 1
    Protein for Rat Sodium/potassium/calcium exchanger 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Alternatively spliced isoforms of the rat eye sodium/calcium+potassium exchanger NCKX1."
      Poon S. , Leach S. , Li X.-F. , Tucker J.E. , Schnetkamp P.P.M. , Lytton J.
      Am. J. Physiol.278:C651-C660(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING
      strain: Sprague-Dawley.
      tissue: Eye.
    2. 2.
      White K.E. , Gesek F.A. , Friedman P.A.
      Submitted (1996-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1067-1155
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