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Index > Protein center > NDUFA12(Gene name) > Human
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  • NDUFA12 (Gene name),
  • NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (Protein name ),  NDUAC_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NDUFA12(DAP13);
    Protein name:
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12;
    Alternative:
    Complex I-B17.2(CI-B17.2;CIB17.2);13 kDa differentiation-associated protein;NADH-ubiquinone oxidoreductase subunit B17.2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Complex I is composed of 45 different subunits.
    Function:
    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    Subcellular Location:
    Mitochondrion inner membrane Peripheral membrane protein Matrix side
    Protein Attributes:
    Sequence length:
    145
    Sequence:
    50:
    MELVQVLKRG | LQQITGHGGL | RGYLRVFFRT | NDAKVGTLVG | EDKYGNKYYE | 
    100:
    DNKQFFGRHR | WVVYTTEMNG | KNTFWDVDGS | MVPPEWHRWL | HSMTDDPPTT | 
    145:
    KPLTARKFIW | TNHKFNVTGT | PEQYVPYSTT | RKKIQEWIPP | STPYK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    ELISA Kit for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    ELISA Kit for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    CLIA Kit for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    CLIA Kit for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    CLIA Kit for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    Polyclonal Antibody for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    Polyclonal Antibody for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    Polyclonal Antibody for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    Monoclonal Antibody for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    Monoclonal Antibody for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    Monoclonal Antibody for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    Protein for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    Protein for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
    Protein for Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of the human complex I NDUFB7 and 17.2-kDa cDNAs and mutational analysis of 19 genes of the HP fraction in complex I-deficient-patients."
      Triepels R. , Smeitink J. , Loeffen J. , Smeets R. , Trijbels F. , van den Heuvel L.
      Hum. Genet.106:385-391(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Adrenal gland.
    3. 3.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-104
    4. 4.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-104
      tissue: Kidney.
    6. 6.
      "The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification."
      Murray J. , Zhang B. , Taylor S.W. , Oglesbee D. , Fahy E. , Marusich M.F. , Ghosh S.S. , Capaldi R.A.
      J. Biol. Chem.278:13619-13622(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE NADH-UBIQUINONE OXIDOREDUCTASE COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 8.
      "Respiratory chain complex I deficiency due to NDUFA12 mutations as a new cause of Leigh syndrome."
      Ostergaard E. , Rodenburg R.J. , van den Brand M. , Thomsen L.L. , Duno M. , Batbayli M. , Wibrand F. , Nijtmans L.
      J. Med. Genet.48:737-740(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN LS
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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