NDUFV1 ELISA Kit for Human(Homo sapiens) | EIAab.comNDUFV1 ELISA Kit for Human(Homo sapiens)

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NDUFV1 (Gene name),

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (Protein name ), NDUV1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

NDUFV1(UQOR1);

Protein name:

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial;

Alternative:

NADH dehydrogenase flavoprotein 1;Complex I-51kD(CI-51kD);NADH-ubiquinone oxidoreductase 51 kDa subunit;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

Function:

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subcellular Location:

Mitochondrion inner membrane Peripheral membrane protein Matrix side

Protein Attributes:

Sequence length:

464

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

464:

QRFAQQHQAR | QAAS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.7744

SMR:

P49821

MIM:

161015

Pfam:

PF01512

String:

P49821

KEGG:

hsa:4723

STRING:

9606.ENSP00000322450

Uniprot:

P49821

FOR

ELISA Kit for Human NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

CLIA Kit for Human NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

Polyclonal Antibody for Human NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

Monoclonal Antibody for Human NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

Protein for Human NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The structure of the human NDUFV1 gene encoding the 51-kDa subunit of mitochondrial complex I."
de Coo R.F.M. , Buddiger P.A. , Smeets H.J.M. , van Oost B.A.
Mamm. Genome10:49-53(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Cloning of the human mitochondrial 51 kDa subunit (NDUFV1) reveals a 100% antisense homology of its 3'UTR with the 5'UTR of the gamma-interferon inducible protein (IP-30) precursor: is this a link between mitochondrial myopathy and inflammation?"
Schuelke M. , Loeffen J. , Mariman E. , Smeitink J. , van den Heuvel L.
Biochem. Biophys. Res. Commun.245:599-606(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
3.

"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning."
Hu R.-M. , Han Z.-G. , Song H.-D. , Peng Y.-D. , Huang Q.-H. , Ren S.-X. , Gu Y.-J. , Huang C.-H. , Li Y.-B. , Jiang C.-L. , Fu G. , Zhang Q.-H. , Gu B.-W. , Dai M. , Mao Y.-F. , Gao G.-F. , Rong R. , Ye M. , more...
Proc. Natl. Acad. Sci. U.S.A.97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pituitary.
4.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Brain.
tissue: Eye.
7.

"The human mitochondrial NADH: ubiquinone oxidoreductase 51-kDa subunit maps adjacent to the glutathione S-transferase P1-1 gene on chromosome 11q13."
Spencer S.R. , Taylor J.B. , Cowell I.G. , Xia C.L. , Pemble S.E. , Ketterer B.
Genomics14:1116-1118(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-130
8.

"Chromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13."
Ali S.T. , Duncan A.M.V. , Schappert K.T. , Heng H.H.Q. , Tsui L.-C. , Chow W. , Robinson B.H.
Genomics18:435-439(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 87-305
tissue: Kidney.
9.

"The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification."
Murray J. , Zhang B. , Taylor S.W. , Oglesbee D. , Fahy E. , Marusich M.F. , Ghosh S.S. , Capaldi R.A.
J. Biol. Chem.278:13619-13622(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE NADH-UBIQUINONE OXIDOREDUCTASE COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY
10.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.

"Mutant NDUFV1 subunit of mitochondrial complex I causes leukodystrophy and myoclonic epilepsy."
Schuelke M. , Smeitink J. , Mariman E. , Loeffen J. , Plecko B. , Trijbels F. , Stockler-Ipsiroglu S. , van den Heuvel L.
Nat. Genet.21:260-261(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MT-C1D VAL-341;VARIANT LS MET-423
12.

"Large-scale deletion and point mutations of the nuclear NDUFV1 and NDUFS1 genes in mitochondrial complex I deficiency."
Benit P. , Chretien D. , Kadhom N. , de Lonlay-Debeney P. , Cormier-Daire V. , Cabral A. , Peudenier S. , Rustin P. , Munnich A. , Roetig A.
Am. J. Hum. Genet.68:1344-1352(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MT-C1D LYS-214

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