NFATC1 ELISA Kit for Pig(Sus scrofa) | EIAab.comNFATC1 ELISA Kit for Pig(Sus scrofa)

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NFATC1 (Gene name),

Nuclear factor of activated T-cells, cytoplasmic 1 (Protein name ), NFAC1_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

NFATC1(NFAT2;NFATC);

Protein name:

Nuclear factor of activated T-cells, cytoplasmic 1(NF-ATc1;NFATc1);

Alternative:

NFATmac;NFAT transcription complex cytosolic component(NF-ATc;NFATc);

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Member of the multicomponent NFATC transcription complex that consists of at least two components, a pre-existing cytoplasmic component NFATC2 and an inducible nuclear component NFATC1. Other members such as NFATC4, NFATC3 or members of the activating protein-1 family, MAF, GATA4 and Cbp/p300 can also bind the complex. NFATC proteins bind to DNA as monomers.

Function:

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells.

Subcellular Location:

Cytoplasm Nucleus Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.

Protein Attributes:

Sequence length:

822

Sequence:

50:

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822:

APQLHPLNLS | QSIVTRLTEP | QP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

ssc:397318

UniGene:

Ssc.52037

Pfam:

PF00554

SMR:

O77638

Uniprot:

O77638

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ELISA Kit for Pig NF-ATc1

Cat.:

E1519h

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Packing:

96T

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ELISA Kit for Pig NF-ATc1

Cat.:

E1519m

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Manual:

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96T

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ELISA Kit for Pig NF-ATc1

Cat.:

E1519b

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MSDS:

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Packing:

96T

ELISA Kit for Pig NF-ATc1

Cat.:

E1519p

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Packing:

96T

CLIA Kit for Pig NF-ATc1

Cat.:

U1519b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig NF-ATc1

Cat.:

U1519m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig NF-ATc1

Cat.:

U1519p

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig NF-ATc1

Cat.:

U1519h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Pig NF-ATc1

Cat.:

P1519Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig NF-ATc1

Cat.:

P1519Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig NF-ATc1

Monoclonal Antibody for Pig NF-ATc1

Protein for Pig NF-ATc1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A viral mechanism for inhibition of the cellular phosphatase calcineurin."
Miskin J.E. , Abrams C.C. , Goatley L.C. , Dixon L.K.
Science281:562-565(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Alveolar macrophage.

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