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Index > Protein center > KLRC2(Gene name) > Human
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  • KLRC2 (Gene name),
  • NKG2-C type II integral membrane protein (Protein name ),  NKG2C_HUMAN from NCBI database.
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  • Gene name:
    KLRC2(NKG2C);
    Protein name:
    NKG2-C type II integral membrane protein;
    Alternative:
    NK cell receptor C;CD159 antigen-like family member C;NKG2-C-activating NK receptor;
    CD:
    CD159c;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Can form disulfide-bonded heterodimer with CD94. Interacts with TYROBP.
    Function:
    Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    231
    Sequence:
    50:
    MSKQRGTFSE | VSLAQDPKRQ | QRKPKGNKSS | ISGTEQEIFQ | VELNLQNPSL | 
    100:
    NHQGIDKIYD | CQGLLPPPEK | LTAEVLGIIC | IVLMATVLKT | IVLIPFLEQN | 
    150:
    NSSPNTRTQK | ARHCGHCPEE | WITYSNSCYY | IGKERRTWEE | SLLACTSKNS | 
    200:
    SLLSIDNEEE | MKFLASILPS | SWIGVFRNSS | HHPWVTINGL | AFKHKIKDSD | 
    231:
    NAELNCAVLQ | VNRLKSAQCG | SSMIYHCKHK | L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    MIM:
    Pfam:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human NKG2-C type II integral membrane protein
    Cat.:
    E9252h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human NKG2-C type II integral membrane protein
    Cat.:
    U9252h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human NKG2-C type II integral membrane protein
    Cat.:
    P9252Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human NKG2-C type II integral membrane protein
    Protein for Human NKG2-C type II integral membrane protein

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells."
      Houchins J.P. , Yabe T. , McSherry C. , Bach F.H.
      J. Exp. Med.173:1017-1020(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex."
      Glienke J. , Sobanov Y. , Brostjan C. , Steffens C. , Nguyen C. , Lehrach H. , Hofer E. , Francis F.
      Immunogenetics48:163-173(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Conservation and variation in human and common chimpanzee CD94 and NKG2 genes."
      Shum B.P. , Flodin L.R. , Muir D.G. , Rajalingam R. , Khakoo S.I. , Cleland S. , Guethlein L.A. , Uhrberg M. , Parham P.
      J. Immunol.168:240-252(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS ASN-2 AND PHE-102
    4. 4.
      Biassoni R.
      Submitted (1997-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Lymphoid tissue.
    5. 5.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    7. 7.
      "The structural basis for intramembrane assembly of an activating immunoreceptor complex."
      Call M.E. , Wucherpfennig K.W. , Chou J.J.
      Nat. Immunol.11:1023-1029(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 72-100 IN COMPLEX WITH TYROBP;INTERACTION WITH TYROBP
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