NNT ELISA Kit for Human(Homo sapiens) | EIAab.comNNT ELISA Kit for Human(Homo sapiens)

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Index > Protein center > NNT(Gene name) > Human

NNT (Gene name),

NAD(P) transhydrogenase, mitochondrial (Protein name ), NNTM_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

NNT;

Protein name:

NAD(P) transhydrogenase, mitochondrial;

Alternative:

Pyridine nucleotide transhydrogenase;Nicotinamide nucleotide transhydrogenase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer.

Function:

The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

Subcellular Location:

Mitochondrion inner membrane Multi-pass membrane protein Matrix side

Protein Attributes:

Sequence length:

1086

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1086:

AVDNPIFYKP | NTAMLLGDAK | KTCDALQAKV | RESYQK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q13423

UniGene:

Hs.482043

STRING:

9606.ENSP00000264663

KEGG:

hsa:23530

MIM:

607878

SMR:

Q13423

Pfam:

PF01262

Uniprot:

Q13423

FOR

ELISA Kit for Human NAD(P) transhydrogenase, mitochondrial

CLIA Kit for Human NAD(P) transhydrogenase, mitochondrial

Polyclonal Antibody for Human NAD(P) transhydrogenase, mitochondrial

Monoclonal Antibody for Human NAD(P) transhydrogenase, mitochondrial

Protein for Human NAD(P) transhydrogenase, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and deduced amino acid sequence of human nicotinamide nucleotide transhydrogenase."
Ware J. , Zieger B.
DNA Seq.7:369-374(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The cDNA sequence of proton-pumping nicotinamide nucleotide transhydrogenase from man and mouse."
Lagberg E.M. , Betsholtz C. , Rydstrom J.
Biochim. Biophys. Acta1273:203-205(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Heart.
3.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Skeletal muscle.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-70 AND LYS-397;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
6.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
7.

"Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency."
Meimaridou E. , Kowalczyk J. , Guasti L. , Hughes C.R. , Wagner F. , Frommolt P. , Nurnberg P. , Mann N.P. , Banerjee R. , Saka H.N. , Chapple J.P. , King P.J. , Clark A.J. , Metherell L.A.
Nat. Genet.44:740-742(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;VARIANTS GCCD4 ASN-193; ALA-357; PRO-365; LEU-437; VAL-533; ARG-664; ARG-678; ASP-862; PRO-977; PRO-1008 AND LYS-1009
8.

"The high-resolution structure of the NADP(H)-binding component (dIII) of proton-translocating transhydrogenase from human heart mitochondria."
White S.A. , Peake S.J. , McSweeney S. , Leonard G. , Cotton N.P.J. , Jackson J.B.
Structure8:1-12(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 880-1086 IN COMPLEX WITH NADP

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