NOMO2 ELISA Kit for Human(Homo sapiens) | EIAab.comNOMO2 ELISA Kit for Human(Homo sapiens)

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NOMO2 (Gene name),

Nodal modulator 2 (Protein name ), NOMO2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

NOMO2;

Protein name:

Nodal modulator 2;

Alternative:

pM5 protein 2;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Forms a complex with NCLN and TMEM147, resulting in a stabilization of the 3 proteins, which are otherwise quickly degraded by the proteasome.

Function:

May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN.

Subcellular Location:

Endoplasmic reticulum membrane Single-pass membrane protein

Protein Attributes:

Sequence length:

1267

Sequence:

50:

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1150:

1200:

1250:

1267:

PFASEILLET | TATCIHY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:283820

UniGene:

Hs.460141

MIM:

609158

String:

Q5JPE7

SMR:

Q5JPE7

Pfam:

PF09430

STRING:

9606.ENSP00000370883

Uniprot:

Q5JPE7

FOR

ELISA Kit for Human Nodal modulator 2

CLIA Kit for Human Nodal modulator 2

Polyclonal Antibody for Human Nodal modulator 2

Monoclonal Antibody for Human Nodal modulator 2

Protein for Human Nodal modulator 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Lymph node.
2.

"The sequence and analysis of duplication-rich human chromosome 16."
Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
tissue: Leukocyte.
tissue: Testis.
4.

"Nicalin and its binding partner Nomo are novel Nodal signaling antagonists."
Haffner C. , Frauli M. , Topp S. , Irmler M. , Hofmann K. , Regula J.T. , Bally-Cuif L. , Haass C.
EMBO J.23:3041-3050(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NCLN;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
5.

"The Nicastrin-like protein Nicalin regulates assembly and stability of the Nicalin-nodal modulator (NOMO) membrane protein complex."
Haffner C. , Dettmer U. , Weiler T. , Haass C.
J. Biol. Chem.282:10632-10638(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NCLN;SUBCELLULAR LOCATION
6.

"Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex."
Dettmer U. , Kuhn P.H. , Abou-Ajram C. , Lichtenthaler S.F. , Kruger M. , Kremmer E. , Haass C. , Haffner C.
J. Biol. Chem.285:26174-26181(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NCLN AND TMEM147

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