Npc1 ELISA Kit for Mouse(Mus musculus) | EIAab.comNpc1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Npc1(Gene name) > Mouse

Npc1 (Gene name),

Niemann-Pick C1 protein (Protein name ), NPC1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Npc1;

Protein name:

Niemann-Pick C1 protein;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with TMEM97.

Function:

Involved in the intracellular trafficking of cholesterol. May play a role in vesicular trafficking in glia, a process that may be crucial for maintaining the structural and functional integrity of nerve terminals.

Subcellular Location:

Late endosome membrane Multi-pass membrane protein Lysosome membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

1278

Sequence:

50:

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1150:

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1250:

1278:

IGPSVNKAKR | HTTYERYRGT | ERERLLNF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

O35604

KEGG:

mmu:18145

UniGene:

Mm.3484

Pfam:

PF02460

String:

O35604

Uniprot:

O35604

FOR

ELISA Kit for Mouse Niemann-Pick C1 protein

Cat.:

E15432h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Mouse Niemann-Pick C1 protein

Cat.:

E15432m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Niemann-Pick C1 protein

Cat.:

E15432p

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Niemann-Pick C1 protein

Cat.:

U15432p

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Niemann-Pick C1 protein

Cat.:

U15432h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Niemann-Pick C1 protein

Cat.:

U15432m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Niemann-Pick C1 protein

Cat.:

P15432Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Niemann-Pick C1 protein

Cat.:

P15432Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Niemann-Pick C1 protein

Protein for Mouse Niemann-Pick C1 protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene."
Loftus S.K. , Morris J.A. , Carstea E.D. , Gu J.Z. , Cummings C. , Brown A. , Ellison J. , Ohno K. , Rosenfeld M.A. , Tagle D.A. , Pentchev P.G. , Pavan W.J.
Science277:232-235(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann-Pick type C disease."
Patel S.C. , Suresh S. , Kumar U. , Hu C.Y. , Cooney A. , Blanchette-Mackie E.J. , Neufeld E.B. , Patel R.C. , Brady R.O. , Patel Y.C. , Pentchev P.G. , Ong W.-Y.
Proc. Natl. Acad. Sci. U.S.A.96:1657-1662(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
5.

"Function of the Niemann-Pick type C proteins and their bypass by cyclodextrin."
Vance J.E. , Peake K.B.
Curr. Opin. Lipidol.22:204-209(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
6.

"Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding."
Deffieu M.S. , Pfeffer S.R.
Proc. Natl. Acad. Sci. U.S.A.108:18932-18936(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NPC2;SUBCELLULAR LOCATION;GLYCOSYLATION

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