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Index > Protein center > NPVF(Gene name) > Human
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  • NPVF (Gene name),
  • Pro-FMRFamide-related neuropeptide VF (Protein name ),  NPVF_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NPVF(C7orf9;RFRP);
    Protein name:
    Pro-FMRFamide-related neuropeptide VF;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine-induced analgesia.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    196
    Sequence:
    50:
    MEIISSKLFI | LLTLATSSLL | TSNIFCADEL | VISNLHSKEN | YDKYSEPRGY | 
    100:
    PKGERSLNFE | ELKDWGPKNV | IKMSTPAVNK | MPHSFANLPL | RFGRNVQEER | 
    150:
    SAGATANLPL | RSGRNMEVSL | VRRVPNLPQR | FGRTTTAKSV | CRMLSDLCQG | 
    196:
    SMHSPCANDL | FYSMTCQHQE | IQNPDQKQSR | RLLFKKIDDA | ELKQEK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Pro-FMRFamide-related neuropeptide VF
    ELISA Kit for Human Pro-FMRFamide-related neuropeptide VF
    ELISA Kit for Human Pro-FMRFamide-related neuropeptide VF
    ELISA Kit for Human Pro-FMRFamide-related neuropeptide VF
    ELISA Kit for Human Pro-FMRFamide-related neuropeptide VF
    ELISA Kit for Human Pro-FMRFamide-related neuropeptide VF
    ELISA Kit for Human Pro-FMRFamide-related neuropeptide VF
    ELISA Kit for Human Pro-FMRFamide-related neuropeptide VF
    CLIA Kit for Human Pro-FMRFamide-related neuropeptide VF
    CLIA Kit for Human Pro-FMRFamide-related neuropeptide VF
    CLIA Kit for Human Pro-FMRFamide-related neuropeptide VF
    CLIA Kit for Human Pro-FMRFamide-related neuropeptide VF
    CLIA Kit for Human Pro-FMRFamide-related neuropeptide VF
    CLIA Kit for Human Pro-FMRFamide-related neuropeptide VF
    CLIA Kit for Human Pro-FMRFamide-related neuropeptide VF
    CLIA Kit for Human Pro-FMRFamide-related neuropeptide VF
    Polyclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Polyclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Polyclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Polyclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Polyclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Polyclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Polyclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Polyclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Monoclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Monoclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Monoclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Monoclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Monoclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Monoclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Monoclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Monoclonal Antibody for Human Pro-FMRFamide-related neuropeptide VF
    Protein for Human Pro-FMRFamide-related neuropeptide VF
    Protein for Human Pro-FMRFamide-related neuropeptide VF
    Protein for Human Pro-FMRFamide-related neuropeptide VF
    Protein for Human Pro-FMRFamide-related neuropeptide VF
    Protein for Human Pro-FMRFamide-related neuropeptide VF
    Protein for Human Pro-FMRFamide-related neuropeptide VF
    Protein for Human Pro-FMRFamide-related neuropeptide VF
    Protein for Human Pro-FMRFamide-related neuropeptide VF

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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SYNTHESIS OF RFRP-1; RFRP-2 AND NPVF;FUNCTION
      tissue: Fetal brain.
    2. 2.
      "Identification and characterization of novel mammalian neuropeptide FF-like peptides that attenuate morphine-induced antinociception."
      Liu Q. , Guan X.-M. , Martin W.J. , McDonald T.P. , Clements M.K. , Jiang Q. , Zeng Z. , Jacobson M. , Williams D.L. Jr. , Yu H. , Bomford D. , Figueroa D. , Mallee J. , Wang R. , Evans J. , Gould R. , Austin C.P.
      J. Biol. Chem.276:36961-36969(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);VARIANT MET-32
    3. 3.
      "Genomic structure and assessment of the retinally expressed RFamide-related peptide gene in dominant cystoid macular dystrophy."
      Schulz H.L. , Stoehr H. , White K. , van Driel M.A. , Hoyng C.B. , Cremers F. , Weber B.H.F.
      Mol. Vis.8:67-71(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1);TISSUE SPECIFICITY;VARIANT GLY-42
      tissue: Retina.
    4. 4.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Human chromosome 7: DNA sequence and biology."
      Scherer S.W. , Cheung J. , MacDonald J.R. , Osborne L.R. , Nakabayashi K. , Herbrick J.-A. , Carson A.R. , Parker-Katiraee L. , Skaug J. , Khaja R. , Zhang J. , Hudek A.K. , Li M. , Haddad M. , Duggan G.E. , Fernandez B.A. , Kanematsu E. , Gentles S. , more...
      Science300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT MET-32
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT MET-32
    7. 7.
      "Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis."
      Ubuka T. , Morgan K. , Pawson A.J. , Osugi T. , Chowdhury V.S. , Minakata H. , Tsutsui K. , Millar R.P. , Bentley G.E.
      PLoS ONE4:E8400-E8400(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 81-92 AND 124-131;AMIDATION AT PHE-92 AND PHE-131;FUNCTION;TISSUE SPECIFICITY;MASS SPECTROMETRY
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