Nr0b2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comNr0b2 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Nr0b2(Gene name) > Rat

Nr0b2 (Gene name),

Nuclear receptor subfamily 0 group B member 2 (Protein name ), NR0B2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Nr0b2(Shp);

Protein name:

Nuclear receptor subfamily 0 group B member 2;

Alternative:

Small heterodimer partner;Orphan nuclear receptor SHP;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Heterodimer; efficient DNA binding requires dimerization with another bHLH protein. Interacts (via N-terminus) with NEUROD1 (via N-terminus an C-terminus). Interacts with ID2. Interacts with NR1I3 and EID1 (By similarity). Interacts with RARA, RXRA, THRB, NR5A1, NR5A2, PPARA and PPARG. May also interact with HNF4A.

Function:

Acts as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated trancription complex for NEUROD1.

Subcellular Location:

Cytoplasm Nucleus Colocalizes with NEUROD1 in the nucleus.

Protein Attributes:

Sequence length:

260

Sequence:

50:

100:

150:

200:

250:

260:

ELLEDMLLLR |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00104

UniGene:

Rn.10712

STRING:

10116.ENSRNOP00000009683

String:

P97947

KEGG:

rno:117274

Uniprot:

P97947

FOR

ELISA Kit for Rat Nuclear receptor subfamily 0 group B member 2

CLIA Kit for Rat Nuclear receptor subfamily 0 group B member 2

Polyclonal Antibody for Rat Nuclear receptor subfamily 0 group B member 2

Monoclonal Antibody for Rat Nuclear receptor subfamily 0 group B member 2

Protein for Rat Nuclear receptor subfamily 0 group B member 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"An orphan nuclear receptor lacking a zinc-finger DNA-binding domain: interaction with several nuclear receptors."
Masuda N. , Yasumo H. , Tamura T. , Hashiguchi N. , Furusawa T. , Tsukamoto T. , Sadano H. , Osumi T.
Biochim. Biophys. Acta1350:27-32(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];INTERACTION WITH HNF4A; RARA; RXRA; PPARA AND THRB;TISSUE SPECIFICITY
strain: Fischer 344-Jcl.
strain: Sprague-Dawley.
tissue: Liver.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Liver.
3.

"Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1."
Li Y. , Choi M. , Cavey G. , Daugherty J. , Suino K. , Kovach A. , Bingham N.C. , Kliewer S.A. , Xu H.E.
Mol. Cell17:491-502(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 17-28 IN COMPLEX WITH NR5A1
4.

"Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner."
Li Y. , Choi M. , Suino K. , Kovach A. , Daugherty J. , Kliewer S.A. , Xu H.E.
Proc. Natl. Acad. Sci. U.S.A.102:9505-9510(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 16-26 IN COMPLEX WITH NR5A2 AND OF 115-131 IN COMPLEX WITH PPARG

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