Nrxn1 ELISA Kit for Mouse(Mus musculus) | EIAab.comNrxn1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Nrxn1(Gene name) > Mouse

Nrxn1 (Gene name),

Neurexin-1-alpha (Protein name ), NRX1A_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Nrxn1(Kiaa0578);

Protein name:

Neurexin-1-alpha;

Alternative:

Neurexin-1-alpha;Neurexin I-alpha;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

The cytoplasmic C-terminal region binds to CASK, CASKIN1 and APBA1. The laminin G-like domain 2 binds to NXPH1 (By similarity). Interacts with SYT13 and SYTL1.

Function:

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

1514

Sequence:

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1514:

ANKNKKNKDK | EYYV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9CS84

UniGene:

Mm.491332

UniGene:

Mm.312068

KEGG:

mmu:18189

Pfam:

PF02210

String:

Q9CS84

Uniprot:

Q9CS84

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ELISA Kit for Mouse Neurexin-1-alpha

Cat.:

E15156h

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96T

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ELISA Kit for Mouse Neurexin-1-alpha

Cat.:

E15156m

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96T

ELISA Kit for Mouse Neurexin-1-alpha

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E15156r

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96T

ELISA Kit for Mouse Neurexin-1-alpha

Cat.:

E15156b

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96T

ELISA Kit for Mouse Neurexin-1-alpha

Cat.:

E15156c

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96T

CLIA Kit for Mouse Neurexin-1-alpha

Cat.:

U15156c

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96T

CLIA Kit for Mouse Neurexin-1-alpha

Cat.:

U15156r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Neurexin-1-alpha

Cat.:

U15156m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Neurexin-1-alpha

Cat.:

U15156h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Neurexin-1-alpha

Cat.:

U15156b

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96T

Polyclonal Antibody for Mouse Neurexin-1-alpha

Cat.:

P15156Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Neurexin-1-alpha

Cat.:

P15156Rb-m

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Polyclonal Antibody for Mouse Neurexin-1-alpha

Cat.:

P15156Rb-r

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40ug/0.2ml

Monoclonal Antibody for Mouse Neurexin-1-alpha

Protein for Mouse Neurexin-1-alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Hara Y. , Nagase T. , Ohara O. , Koga H.
DNA Res.9:179-188(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2A)
tissue: Brain.
2.

Okazaki N. , Kikuno R. , Nagase T. , Ohara O. , Koga H.
Submitted (2003-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];ALTERNATIVE SPLICING
strain: C57BL/6J.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4A)
tissue: Eye.
5.

"Sequencing of the neurexin genes."
Graveley B.R. , Philipps D.L.
Submitted (2001-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 298-437 (ISOFORMS 1A; 2A AND 3A/4A)
strain: CD-1.
tissue: Brain.
6.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1126-1514 (ISOFORMS 1A/2A/3A)
strain: C57BL/6J.
tissue: Embryo.
7.

"Differential seizure-induced and developmental changes of neurexin expression."
Gorecki D.C. , Szklarczyk A. , Lukasiuk K. , Kaczmarek L. , Simons J.P.
Mol. Cell. Neurosci.13:218-227(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1463-1505 (ISOFORMS 1A/2A/3A/4A)
strain: C57BL/10.
tissue: Brain.
8.

"Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action."
Geppert M. , Khvotchev M. , Krasnoperov V. , Goda Y. , Missler M. , Hammer R.E. , Ichtchenko K. , Petrenko A.G. , Sudhof T.C.
J. Biol. Chem.273:1705-1710(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION;CALCIUM-DEPENDENT INTERACTION WITH ALPHA-LATROTOXIN
9.

"Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins."
Fukuda M. , Mikoshiba K.
Biochem. Biophys. Res. Commun.281:1226-1233(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SYTL1
10.

"Characterization of KIAA1427 protein as an atypical synaptotagmin (Syt XIII)."
Fukuda M. , Mikoshiba K.
Biochem. J.354:249-257(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SYT13
11.

"Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis."
Missler M. , Zhang W. , Rohlmann A. , Kattenstroth G. , Hammer R.E. , Gottmann K. , Sudhof T.C.
Nature423:939-948(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION IN NEUROTRANSMITTER RELEASE
12.

"Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins."
Kattenstroth G. , Tantalaki E. , Sudhof T.C. , Gottmann K. , Missler M.
Proc. Natl. Acad. Sci. U.S.A.101:2607-2612(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
13.

"Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules."
Dudanova I. , Sedej S. , Ahmad M. , Masius H. , Sargsyan V. , Zhang W. , Riedel D. , Angenstein F. , Schild D. , Rupnik M. , Missler M.
J. Neurosci.26:10599-10613(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
14.

"alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction."
Sons M.S. , Busche N. , Strenzke N. , Moser T. , Ernsberger U. , Mooren F.C. , Zhang W. , Ahmad M. , Steffens H. , Schomburg E.D. , Plomp J.J. , Missler M.
Neuroscience138:433-446(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
15.

"Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation."
Dudanova I. , Tabuchi K. , Rohlmann A. , Sudhof T.C. , Missler M.
J. Comp. Neurol.502:261-274(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
16.

"Unusually rapid evolution of neuroligin-4 in mice."
Bolliger M.F. , Pei J. , Maxeiner S. , Boucard A.A. , Grishin N.V. , Sudhof T.C.
Proc. Natl. Acad. Sci. U.S.A.105:6421-6426(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NLGN4L
17.

"Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments."
Etherton M.R. , Blaiss C.A. , Powell C.M. , Sudhof T.C.
Proc. Natl. Acad. Sci. U.S.A.106:17998-18003(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
18.

"Cbln family proteins promote synapse formation by regulating distinct neurexin signaling pathways in various brain regions."
Matsuda K. , Yuzaki M.
Eur. J. Neurosci.33:1447-1461(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH CBLN1; CBLN2 AND CBLN4
19.

"Crystal structures of beta-neurexin 1 and beta-neurexin 2 ectodomains and dynamics of splice insertion sequence 4."
Koehnke J. , Jin X. , Trbovic N. , Katsamba P.S. , Brasch J. , Ahlsen G. , Scheiffele P. , Honig B. , Palmer A.G. III , Shapiro L.
Structure16:410-421(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 1132-1334 (ISOFORM 5A) IN COMPLEX WITH CALCIUM;SUBUNIT;INTERACTION WITH NLGN1 AND NLGN2;ALTERNATIVE SPLICING
20.

"Splice form dependence of beta-neurexin/neuroligin binding interactions."
Koehnke J. , Katsamba P.S. , Ahlsen G. , Bahna F. , Vendome J. , Honig B. , Shapiro L. , Jin X.
Neuron67:61-74(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.69 ANGSTROMS) OF 1132-1334;INTERACTION WITH NLGN1; NLGN2 AND NLGN3

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