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Index > Protein center > LAT2(Gene name) > Chicken
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  • LAT2 (Gene name),
  • Linker for activation of T-cells family member 2 (Protein name ),  NTAL_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LAT2(LAB;NTAL);
    Protein name:
    Linker for activation of T-cells family member 2;
    Alternative:
    Non-T-cell activation linker;Linker for activation of B-cells;
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    When phosphorylated, interacts with GRB2.
    Function:
    Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells. May also be involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization through the recruitment of GRB2.
    Subcellular Location:
    Cell membrane Single-pass type III membrane protein Present in lipid rafts.
    Protein Attributes:
    Sequence length:
    198
    Sequence:
    50:
    MAQPELLWAA | AGLMLLGVAV | SACVRCQLYA | TKRGKDGSQG | SRLERPQRFE | 
    100:
    VIRSCSAVTR | RPERIKEPEH | LARKAPEELS | TSCHVGFESS | AEPRYQNFLT | 
    150:
    EDCLHEDAAY | VEPVPLDYYS | HNRFFSPPND | EDSHSYQNVI | IGDPCSSELD | 
    198:
    DAEDYENSTA | IEVWKVQQAK | AMLYAESQDE | EPDYVNTDPT | IDAVVLSK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken Linker for activation of T-cells family member 2
    ELISA Kit for Chicken Linker for activation of T-cells family member 2
    ELISA Kit for Chicken Linker for activation of T-cells family member 2
    ELISA Kit for Chicken Linker for activation of T-cells family member 2
    CLIA Kit for Chicken Linker for activation of T-cells family member 2
    CLIA Kit for Chicken Linker for activation of T-cells family member 2
    CLIA Kit for Chicken Linker for activation of T-cells family member 2
    CLIA Kit for Chicken Linker for activation of T-cells family member 2
    Polyclonal Antibody for Chicken Linker for activation of T-cells family member 2
    Polyclonal Antibody for Chicken Linker for activation of T-cells family member 2
    Polyclonal Antibody for Chicken Linker for activation of T-cells family member 2
    Polyclonal Antibody for Chicken Linker for activation of T-cells family member 2
    Monoclonal Antibody for Chicken Linker for activation of T-cells family member 2
    Monoclonal Antibody for Chicken Linker for activation of T-cells family member 2
    Monoclonal Antibody for Chicken Linker for activation of T-cells family member 2
    Monoclonal Antibody for Chicken Linker for activation of T-cells family member 2
    Protein for Chicken Linker for activation of T-cells family member 2
    Protein for Chicken Linker for activation of T-cells family member 2
    Protein for Chicken Linker for activation of T-cells family member 2
    Protein for Chicken Linker for activation of T-cells family member 2

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "Grb2 and the non-T cell activation linker NTAL constitute a Ca(2+)-regulating signal circuit in B lymphocytes."
      Stork B. , Engelke M. , Frey J. , Horejsi V. , Hamm-Baarke A. , Schraven B. , Kurosaki T. , Wienands J.
      Immunity21:681-691(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];MUTAGENESIS OF CYS-23 AND CYS-26;PHOSPHORYLATION;INTERACTION WITH GRB2;PHOSPHORYLATION AT TYR-136; TYR-155 AND TYR-184;FUNCTION
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