MT-ND2 ELISA Kit for Human(Homo sapiens) | EIAab.comMT-ND2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MT-ND2(Gene name) > Human

MT-ND2 (Gene name),

NADH-ubiquinone oxidoreductase chain 2 (Protein name ), NU2M_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MT-ND2(MTND2;NADH2;ND2);

Protein name:

NADH-ubiquinone oxidoreductase chain 2;

Alternative:

NADH dehydrogenase subunit 2;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subcellular Location:

Mitochondrion inner membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

347

Sequence:

50:

100:

150:

200:

250:

300:

347:

SITLLPMSNN | VKMKWQFEHT | KPTPFLPTLI | ALTTLLLPIS | PFMLMIL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P03891

Pfam:

PF06444

String:

P03891

KEGG:

hsa:4536

MIM:

502500

Uniprot:

P03891

FOR

ELISA Kit for Human NADH-ubiquinone oxidoreductase chain 2

CLIA Kit for Human NADH-ubiquinone oxidoreductase chain 2

Polyclonal Antibody for Human NADH-ubiquinone oxidoreductase chain 2

Monoclonal Antibody for Human NADH-ubiquinone oxidoreductase chain 2

Protein for Human NADH-ubiquinone oxidoreductase chain 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Sequence and organization of the human mitochondrial genome."
Anderson S. , Bankier A.T. , Barrell B.G. , de Bruijn M.H.L. , Coulson A.R. , Drouin J. , Eperon I.C. , Nierlich D.P. , Roe B.A. , Sanger F. , Schreier P.H. , Smith A.J.H. , Staden R. , Young I.G.
Nature290:457-465(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.

"Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing."
Sanger F. , Coulson A.R. , Barrell B.G. , Smith A.J.H. , Roe B.A.
J. Mol. Biol.143:161-178(1980) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Departure from neutrality at the mitochondrial NADH dehydrogenase subunit 2 gene in humans, but not in chimpanzees."
Wise C.A. , Sraml M. , Easteal S.
Genetics148:409-421(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS VAL-69; SER-88; ASP-150; MET-237; THR-265; VAL-265; THR-278 AND ALA-333
4.

"Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs."
Horai S. , Hayasaka K. , Kondo R. , Tsugane K. , Takahata N.
Proc. Natl. Acad. Sci. U.S.A.92:532-536(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ILE-43; LEU-325 AND THR-331
tissue: Placenta.
5.

"Lineage-specific selection in human mtDNA: lack of polymorphisms in a segment of MTND5 gene in haplogroup J."
Moilanen J.S. , Finnila S. , Majamaa K.
Mol. Biol. Evol.20:2132-2142(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Mitochondrial genome variation and the origin of modern humans."
Ingman M. , Kaessmann H. , Paeaebo S. , Gyllensten U.
Nature408:708-713(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines."
Ingman M. , Gyllensten U.
Genome Res.13:1600-1606(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
8.

"Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians."
Coble M.D. , Just R.S. , O'Callaghan J.E. , Letmanyi I.H. , Peterson C.T. , Irwin J.A. , Parsons T.J.
Int. J. Legal Med.118:137-146(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
9.

"Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase."
Chomyn A. , Mariottini P. , Cleeter M.W.J. , Ragan C.I. , Matsuno-Yagi A. , Hatefi Y. , Doolittle R.F. , Attardi G.
Nature314:592-597(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF PROTEIN
10.

"The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification."
Murray J. , Zhang B. , Taylor S.W. , Oglesbee D. , Fahy E. , Marusich M.F. , Ghosh S.S. , Capaldi R.A.
J. Biol. Chem.278:13619-13622(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE NADH-UBIQUINONE OXIDOREDUCTASE COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY
11.

"Alternative, simultaneous complex I mitochondrial DNA mutations in Leber's hereditary optic neuropathy."
Johns D.R. , Berman J.
Biochem. Biophys. Res. Commun.174:1324-1330(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LHON ASP-150
12.

"Normal variants of human mitochondrial DNA and translation products: the building of a reference data base."
Marzuki S. , Noer A.S. , Lertrit P. , Thyagarajan D. , Kapsa R. , Utthanaphol P. , Byrne E.
Hum. Genet.88:139-145(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LEU-42; ARG-63; ALA-119; PRO-148; SER-150; THR-159 AND ALA-185
13.

"Mitochondrial DNA complex I and III mutations associated with Leber's hereditary optic neuropathy."
Brown M.D. , Voljavec A.S. , Lott M.T. , Torroni A. , Yang C.C. , Wallace D.C.
Genetics130:163-173(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LHON SER-259
14.

"Detection of point mutations in codon 331 of mitochondrial NADH dehydrogenase subunit 2 in Alzheimer's brains."
Lin F.-H. , Lin R. , Wisniewski H.M. , Hwang Y.-W. , Grundke-Iqbal I. , Healy-Louie G. , Iqbal K.
Biochem. Biophys. Res. Commun.182:238-246(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AD-MT SER-331
15.

"Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome."
Rieder M.J. , Taylor S.L. , Tobe V.O. , Nickerson D.A.
Nucleic Acids Res.26:967-973(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THR-57

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