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Index > Protein center > Nusap1(Gene name) > Mouse
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  • Nusap1 (Gene name),
  • Nucleolar and spindle-associated protein 1 (Protein name ),  NUSAP_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Nusap1;
    Protein name:
    Nucleolar and spindle-associated protein 1(NuSAP);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with DNA and microtubules. Microtubule bundling is inhibited by IPO7, KPNA2 and KPNB1 while association with DNA is also inhibited by IPO7 and KPNA2.
    Function:
    Microtubule-associated protein with the capacity to bundle and stabilize microtubules. May associate with chromosomes and promote the organization of mitotic spindle microtubules around them.
    Subcellular Location:
    Cytoplasm Nucleus nucleolus Cytoplasm cytoskeleton spindle Chromosome Found in the cytoplasm and nucleolus during interphase and redistributes to the mitotic spindle in prometaphase. Localizes to the mitotic spindle and to the chromosomes during anaphase and telophase then disappears from around the chromosomes during cytokinesis.
    Protein Attributes:
    Sequence length:
    427
    Sequence:
    50:
    MTVPSAEELD | SFKYSDLQNL | AKRLGLRANM | KADKLLKALK | AHLNPETRKE | 
    100:
    NKNQDENQFS | TDETEIHVSS | EEQAETESGG | HVTKTRRRRR | KKHKTIHGIP | 
    150:
    TSQTLLQDHL | EMKGTDSSNF | QNQENQENQD | PRDTAEVPSL | PEQRPEDGNA | 
    200:
    ASSGEGEVND | IKDSKKPLEK | RSLCTDEFSK | LGNNKRTSAT | TPNFKKLHEA | 
    250:
    RFKKMESIDE | YIMRKKKHLK | EHSSLNELKL | DKKGIVTPVP | PRGRLSVPCT | 
    300:
    PARQQCPQGH | SATKMNVRFS | AATKDNEHKC | SLTKTPARKS | PHVTAPGSAS | 
    350:
    KGQAVFRTPK | SKATERTSIA | VITPFKLMTE | ATQTPSSSKK | PVFDLKASLS | 
    400:
    RPLNYKPHKG | KLKPWGQAKE | NNSLNERVSR | VTFHRKTYKQ | PHLQTREERW | 
    427:
    KRQEQERKEK | KEKLLEARRN | LGVTKAQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse NuSAP
    Cat.:
    E0523h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse NuSAP
    Cat.:
    E0523b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse NuSAP
    Cat.:
    E0523c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse NuSAP
    Cat.:
    E0523m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse NuSAP
    Cat.:
    U0523b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse NuSAP
    Cat.:
    U0523m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse NuSAP
    Cat.:
    U0523c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse NuSAP
    Cat.:
    U0523h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse NuSAP
    Cat.:
    P0523Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse NuSAP
    Polyclonal Antibody for Mouse NuSAP
    Cat.:
    P0523Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse NuSAP
    Monoclonal Antibody for Mouse NuSAP
    Monoclonal Antibody for Mouse NuSAP
    Monoclonal Antibody for Mouse NuSAP
    Monoclonal Antibody for Mouse NuSAP
    Protein for Mouse NuSAP
    Protein for Mouse NuSAP
    Protein for Mouse NuSAP
    Protein for Mouse NuSAP

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    References
    1. 1.
      "A novel nucleolar protein expressed in proliferating cells."
      Sato H. , Tanaka Y. , Taniguchi M.
      Submitted (2000-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: C57BL/6.
      tissue: Liver.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Cerebellum.
      tissue: Embryo.
      tissue: Thymus.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      strain: Czech II.
      strain: FVB/N.
      tissue: Embryonic germ cell.
      tissue: Mammary tumor.
    5. 5.
      "NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization."
      Raemaekers T. , Ribbeck K. , Beaudouin J. , Annaert W. , Van Camp M. , Stockmans I. , Smets N. , Bouillon R. , Ellenberg J. , Carmeliet G.
      J. Cell Biol.162:1017-1029(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ASSOCIATION WITH MICROTUBULES;SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE
    6. 6.
      "Expression analyses and transcriptional regulation of mouse nucleolar spindle-associated protein gene in erythroid cells: essential role of NF-Y."
      Fujiwara T. , Harigae H. , Okitsu Y. , Takahashi S. , Yokoyama H. , Yamada M.F. , Ishizawa K. , Kameoka J. , Kaku M. , Sasaki T.
      Br. J. Haematol.135:583-590(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    7. 7.
      "A role for NuSAP in linking microtubules to mitotic chromosomes."
      Ribbeck K. , Raemaekers T. , Carmeliet G. , Mattaj I.W.
      Curr. Biol.17:230-236(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DNA-BINDING;SUBCELLULAR LOCATION
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