Oas3 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comOas3 ELISA Kit for Rat(Rattus norvegicus)

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Oas3 (Gene name),

2'-5'-oligoadenylate synthase 3 (Protein name ), OAS3_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Oas3;

Protein name:

2'-5'-oligoadenylate synthase 3((2-5')oligo(A) synthase 3);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Monomer.

Function:

Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

1137

Sequence:

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1137:

NARWDLLAKE | AAAYTSALCC | MDKDGNPIKP | WPVKAAV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.162137

KEGG:

rno:494202

SMR:

Q5MYT7

Pfam:

PF01909

Uniprot:

Q5MYT7

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ELISA Kit for Rat (2-5')oligo(A) synthase 3

Cat.:

E1715h

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96T

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ELISA Kit for Rat (2-5')oligo(A) synthase 3

Cat.:

E1715m

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96T

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ELISA Kit for Rat (2-5')oligo(A) synthase 3

Cat.:

E1715r

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96T

CLIA Kit for Rat (2-5')oligo(A) synthase 3

Cat.:

U1715h

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Packing:

96T

CLIA Kit for Rat (2-5')oligo(A) synthase 3

Cat.:

U1715m

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96T

CLIA Kit for Rat (2-5')oligo(A) synthase 3

Cat.:

U1715r

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96T

Polyclonal Antibody for Rat (2-5')oligo(A) synthase 3

Cat.:

P1715Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat (2-5')oligo(A) synthase 3

Cat.:

P1715Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat (2-5')oligo(A) synthase 3

Cat.:

P1715Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat (2-5')oligo(A) synthase 3

Protein for Rat (2-5')oligo(A) synthase 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The mammalian 2'-5' oligoadenylate synthetase gene family: evidence for concerted evolution of paralogous Oas1 genes in Rodentia and Artiodactyla."
Perelygin A.A. , Zharkikh A.A. , Scherbik S.V. , Brinton M.A.
J. Mol. Evol.63:562-576(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Large intestine.

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