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Index > Protein center > Lpcat2(Gene name) > Mouse
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  • Lpcat2 (Gene name),
  • Lysophosphatidylcholine acyltransferase 2 (Protein name ),  PCAT2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Lpcat2(Aytl1;Aytl1a;Lpcat2a);
    Protein name:
    Lysophosphatidylcholine acyltransferase 2(LPC acyltransferase 2;LPCAT-2;LysoPC acyltransferase 2);
    Alternative:
    1-alkylglycerophosphocholine O-acetyltransferase;2.3.1.51;1-acylglycerophosphocholine O-acyltransferase(1-AGP acyltransferase 11);Acyltransferase-like 1(Acetyl-CoA:lyso-PAF acetyltransferase);2.3.1.67;Acetyl-CoA:lyso-platelet-activating factor acetyltransferase(Acetyl-CoA:lyso-PAF acetyltransferase;Lyso-PAF acetyltransferase;LysoPAFAT);Acyltransferase-like 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-alkyl-phosphatidylcholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases.
    Subcellular Location:
    Endoplasmic reticulum membrane Single-pass type II membrane protein Golgi apparatus membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    544
    Sequence:
    50:
    MNRCAEAAAV | AATVPGSGVG | DAGLRPPMVP | RQASFFPPPV | PNPFVQQTTI | 
    100:
    SASRRLQMFL | LGIILLPVRA | LLVGIILLLA | WPFAVISTAC | CPEKLTHPIS | 
    150:
    NWRRKITRPA | LTFLARAMFF | SMGFTVTVKG | KVASPLEAPI | FVVAPHSTFF | 
    200:
    DGIACVVAGL | PSLVSRNENA | QTPLVGRLLR | ALQPVLVSRV | DPDSRKNTIN | 
    250:
    EIKKRATSGG | EWPQILVFPE | GTCTNRSCLI | TFKPGAFIPG | VPVQPVLLRY | 
    300:
    PNKLDTVTWT | WQGYTFLQLC | VLTFCQLFTK | VEIEFMPVQA | PSEEEKNDPV | 
    350:
    LFASRIRNLM | AEALEIPVTD | HTYEDCRLMI | SAGQLTLPME | AGLVEFSKIS | 
    400:
    RKLKLDWDGI | RKHLDEYASI | ASSSKGGRIG | IEEFAEYLKL | PVSDVLRQLF | 
    450:
    ALFDRNNDGS | IDFREYVIGL | AVLCNPANTE | EIIQVAFKLF | DVDEDGYITE | 
    500:
    EEFCTILQAS | LGVPDLNVSG | LFREIAQRDS | VSYEEFKSFA | LKHPEYAKIF | 
    544:
    TTYLDLQTCH | VFSLPEEVQT | APSVASNKVS | PESQEEGTSD | KKVD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse LPC acyltransferase 2
    Cat.:
    E2228h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse LPC acyltransferase 2
    Cat.:
    E2228m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse LPC acyltransferase 2
    Cat.:
    E2228r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse LPC acyltransferase 2
    Cat.:
    U2228r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse LPC acyltransferase 2
    Cat.:
    U2228h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse LPC acyltransferase 2
    Cat.:
    U2228m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse LPC acyltransferase 2
    Cat.:
    P2228Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse LPC acyltransferase 2
    Cat.:
    P2228Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse LPC acyltransferase 2
    Cat.:
    P2228Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse LPC acyltransferase 2
    Monoclonal Antibody for Mouse LPC acyltransferase 2
    Monoclonal Antibody for Mouse LPC acyltransferase 2
    Protein for Mouse LPC acyltransferase 2
    Protein for Mouse LPC acyltransferase 2
    Protein for Mouse LPC acyltransferase 2

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    Linearity
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    References
    1. 1.
      "A single enzyme catalyzes both platelet-activating factor production and membrane biogenesis of inflammatory cells. Cloning and characterization of acetyl-CoA:lyso-PAF acetyltransferase."
      Shindou H. , Hishikawa D. , Nakanishi H. , Harayama T. , Ishii S. , Taguchi R. , Shimizu T.
      J. Biol. Chem.282:6532-6539(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Spinal cord.
    3. 3.
      "Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes."
      Soupene E. , Fyrst H. , Kuypers F.A.
      Proc. Natl. Acad. Sci. U.S.A.105:88-93(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 175-299 (ISOFORM 2);NUCLEOTIDE SEQUENCE [MRNA] OF 175-544 (ISOFORM 3);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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