PCNA ELISA Kit for Bovine(Bos taurus) | EIAab.comPCNA ELISA Kit for Bovine(Bos taurus)

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PCNA (Gene name),

Proliferating cell nuclear antigen (Protein name ), PCNA_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PCNA;

Protein name:

Proliferating cell nuclear antigen(PCNA);

Alternative:

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Homotrimer (By similarity). Forms a complex with activator 1 heteropentamer in the presence of ATP. Interacts with POLH, POLK, DNMT1, ERCC5, FEN1, CDC6 and POLDIP2. Interacts with EXO1 and KCTD10. Forms a ternary complex with DNTTIP2 and core histone. Interacts with PPP1R15A, POLD1, POLD3 and POLD4. Interacts with BAZ1B; the interaction is direct. Interacts with HLTF and SHPRH (By similarity). Interacts with NUDT15 (By similarity). Interaction is disrupted in response to UV irradiation and acetylation. Interacts with CDKN1A/p21(CIP1) and CDT1; interacts via their PIP-box which also recruits the DCX(DTL) complex. Interacts with APEX2; this interaction is triggered by reactive oxygen species and increased by misincorporation of uracil in nuclear DNA. Interacts with DDX11.

Function:

This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.

Subcellular Location:

Nucleus Forms nuclear foci representing sites of ongoing DNA replication and vary in morphology and number during S phase. Together with APEX2, is redistributed in discrete nuclear foci in presence of oxidative DNA damaging agents.

Protein Attributes:

Sequence length:

261

Sequence:

50:

100:

150:

200:

250:

261:

LAPKIEDEEG | S

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Bt.52764

Pfam:

PF02747

KEGG:

bta:515499

String:

Q3ZBW4

STRING:

9913.ENSBTAP00000007967

SMR:

Q3ZBW4

Uniprot:

Q3ZBW4

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ELISA Kit for Bovine PCNA

Cat.:

E0591m

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96T

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ELISA Kit for Bovine PCNA

Cat.:

E0591h

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96T

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ELISA Kit for Bovine PCNA

Cat.:

E0591r

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ELISA Kit for Bovine PCNA

Cat.:

E0591b

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96T

ELISA Kit for Bovine PCNA

Cat.:

E0591c

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96T

CLIA Kit for Bovine PCNA

Cat.:

U0591c

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96T

CLIA Kit for Bovine PCNA

Cat.:

U0591h

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Packing:

96T

CLIA Kit for Bovine PCNA

Cat.:

U0591b

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Packing:

96T

CLIA Kit for Bovine PCNA

Cat.:

U0591m

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Packing:

96T

CLIA Kit for Bovine PCNA

Cat.:

U0591r

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Packing:

96T

Polyclonal Antibody for Bovine PCNA

Cat.:

P0591Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine PCNA

Cat.:

P0591Rb-m

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40ug/0.2ml

Polyclonal Antibody for Bovine PCNA

Cat.:

P0591Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Bovine PCNA

Protein for Bovine PCNA

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2005-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Fetal liver.

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