Protein name:
cGMP-specific 3',5'-cyclic phosphodiesterase ;
Alternative:
cGMP-binding cGMP-specific phosphodiesterase (CGB-PDE) ;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Function:
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.
Subcellular Location:
Cytoplasm
Cytoplasm
cytosol
PDE5A1 and PDE5A2 are located mostly to soluble cellular fractions and some to particulate cellular fractions.
Protein Attributes:
50:
MERGSPGAGA | ARLPRDQDSV | EAWLDDHRDF | TFSYFVKKAT | REMVNAWFAE |
100:
RVHTIPVCKE | GIRGHAESCS | CSSQQSSRAD | SSAPGTPTRK | ISASEFDRPL |
150:
RPIVVKDSEG | TVSFLADSEK | KEQMPLTPPR | FDNDEGDQCS | RLLELVKDIS |
200:
SHLDVTALCH | KIFLHIHGLI | SADRYSLFLV | CEDSSNDKFL | ISRLFDVAEG |
250:
STLEEASNNC | IRLEWNKGIV | GHVAALGEPL | NIKDAYEDPR | FNAEVDQITG |
300:
YKTQSILCMP | IKNHREEVVG | VAQAINKKSG | NGGTFTEKDE | KDFAAYLAFC |
350:
GIVLHNAQLY | ETSLLENKRN | QVLLDLASLI | FEEQQSLEVI | LKKIAATIIS |
400:
FMQVQKCTIF | IVDEDCSDSF | SSVFHMECEE | LEKLPDTLTR | ERDANRINYM |
450:
YAQYVKNTME | PLNIPDVSKD | KRFPWTNENT | GNVNQQCIRS | LLCTPIKNGK |
500:
KNKVIGVCQL | VNKMEENTGK | VKPFNRNDEQ | FLEAFVIFCG | LGIQNTQMYE |
550:
AVERAMAKQM | VTLEVLSYHA | SAAEEETKEL | QSLAAAVVPS | AQTLKITDFS |
600:
FSDFELSDLE | TALCTIRMFT | DLNLVQNFQM | KHEVLCRWIL | SVKKNYRKNV |
650:
AYHNWRHAFN | TAQCMFAALK | AGKIQNKLTD | LEILALLIAA | LSHDLDHRGV |
700:
NNSYIQRSEH | PLAQLYCHSI | MEHHHFDQCL | MILNSPGNQI | LSGLSIEEYK |
750:
TTLKIIKQAI | LATDLALYIK | RRGEFFELIR | KNQFNLEDPH | QKELFLAMLM |
800:
TACDLSAITK | PWPIQQRIAE | LVATEFFDQG | DRERKELNIE | PADLMNREKK |
850:
NKIPSMQVGF | IDAICLQLYE | ALTHVSEDCF | PLLDGCRKNR | QKWQALAEQQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
Dog
ELISA Kit for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
ELISA Kit for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
ELISA Kit for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
ELISA Kit for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
ELISA Kit for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
CLIA Kit for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
CLIA Kit for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
CLIA Kit for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
CLIA Kit for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
CLIA Kit for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Polyclonal Antibody for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Polyclonal Antibody for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Polyclonal Antibody for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Polyclonal Antibody for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Polyclonal Antibody for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Monoclonal Antibody for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Monoclonal Antibody for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Monoclonal Antibody for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Monoclonal Antibody for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Monoclonal Antibody for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Protein for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Protein for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Protein for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Protein for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
Protein for Dog cGMP-specific 3',5'-cyclic phosphodiesterase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS PDE5A1 AND PDE5A2)
tissue :
Lung .