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Index > Protein center > PEX14(Gene name) > Human
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  • PEX14 (Gene name),
  • Peroxisomal membrane protein PEX14 (Protein name ),  PEX14_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PEX14;
    Protein name:
    Peroxisomal membrane protein PEX14;
    Alternative:
    Peroxin-14;PTS1 receptor-docking protein;Peroxisomal membrane anchor protein PEX14;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with PEX5 and PEX19.
    Function:
    Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17.
    Subcellular Location:
    Peroxisome membrane Peripheral membrane protein Cytoplasmic side
    Protein Attributes:
    Sequence length:
    377
    Sequence:
    50:
    MASSEQAEQP | SQPSSTPGSE | NVLPREPLIA | TAVKFLQNSR | VRQSPLATRR | 
    100:
    AFLKKKGLTD | EEIDMAFQQS | GTAADEPSSL | GPATQVVPVQ | PPHLISQPYS | 
    150:
    PAGSRWRDYG | ALAIIMAGIA | FGFHQLYKKY | LLPLILGGRE | DRKQLERMEA | 
    200:
    GLSELSGSVA | QTVTQLQTTL | ASVQELLIQQ | QQKIQELAHE | LAAAKATTST | 
    250:
    NWILESQNIN | ELKSEINSLK | GLLLNRRQFP | PSPSAPKIPS | WQIPVKSPSP | 
    300:
    SSPAAVNHHS | SSDISPVSNE | STSSSPGKEG | HSPEGSTVTY | HLLGPQEEGE | 
    350:
    GVVDVKGQVR | MEVQGEEEKR | EDKEDEEDEE | DDDVSHVDEE | DCLGVQREDR | 
    377:
    RGGDGQINEQ | VEKLRRPEGA | SNESERD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    SMR:
    MIM:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Peroxisomal membrane protein PEX14
    ELISA Kit for Human Peroxisomal membrane protein PEX14
    ELISA Kit for Human Peroxisomal membrane protein PEX14
    CLIA Kit for Human Peroxisomal membrane protein PEX14
    CLIA Kit for Human Peroxisomal membrane protein PEX14
    CLIA Kit for Human Peroxisomal membrane protein PEX14
    Polyclonal Antibody for Human Peroxisomal membrane protein PEX14
    Polyclonal Antibody for Human Peroxisomal membrane protein PEX14
    Polyclonal Antibody for Human Peroxisomal membrane protein PEX14
    Monoclonal Antibody for Human Peroxisomal membrane protein PEX14
    Monoclonal Antibody for Human Peroxisomal membrane protein PEX14
    Monoclonal Antibody for Human Peroxisomal membrane protein PEX14
    Protein for Human Peroxisomal membrane protein PEX14
    Protein for Human Peroxisomal membrane protein PEX14
    Protein for Human Peroxisomal membrane protein PEX14

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Identification of a human PTS1 receptor docking protein directly required for peroxisomal protein import."
      Fransen M. , Terlecky S.R. , Subramani S.
      Proc. Natl. Acad. Sci. U.S.A.95:8087-8092(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH PEX5 AND PEX13;FUNCTION
    2. 2.
      "The peroxin Pex14p. cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysis."
      Shimizu N. , Itoh R. , Hirono Y. , Otera H. , Ghaedi K. , Tateishi K. , Tamura S. , Okumoto K. , Harano T. , Mukai S. , Fujiki Y.
      J. Biol. Chem.274:12593-12604(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain.
      tissue: Cerebellum.
      tissue: Placenta.
    4. 4.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Halleck A. , Ebert L. , Mkoundinya M. , Schick M. , Eisenstein S. , Neubert P. , Kstrang K. , Schatten R. , Shen B. , Henze S. , Mar W. , Korn B. , Zuo D. , Hu Y. , LaBaer J.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Muscle.
    8. 8.
      Bienvenut W.V. , Lempens A. , Norman J.C.
      Submitted (2009-10) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-34; 184-195 AND 352-363;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Ovarian carcinoma.
    9. 9.
      "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis."
      Sacksteder K.A. , Jones J.M. , South S.T. , Li X. , Liu Y. , Gould S.J.
      J. Cell Biol.148:931-944(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PEX19
    10. 10.
      "Identification of a new complementation group of the peroxisome biogenesis disorders and PEX14 as the mutated gene."
      Shimozawa N. , Tsukamoto T. , Nagase T. , Takemoto Y. , Koyama N. , Suzuki Y. , Komori M. , Osumi T. , Jeannette G. , Wanders R.J. , Kondo N.
      Hum. Mutat.23:552-558(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN PBD-CGK AND PBD13A
    11. 11.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-335;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-34;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    17. 17.
      "Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19."
      Neufeld C. , Filipp F.V. , Simon B. , Neuhaus A. , Schueller N. , David C. , Kooshapur H. , Madl T. , Erdmann R. , Schliebs W. , Wilmanns M. , Sattler M.
      EMBO J.28:745-754(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 16-80 IN COMPLEXES WITH PEX5 AND PEX19;MUTAGENESIS OF PHE-52 AND LYS-56;SUBCELLULAR LOCATION;INTERACTION WITH PEX5 AND PEX19
    18. 18.
      "PEX14 is required for microtubule-based peroxisome motility in human cells."
      Bharti P. , Schliebs W. , Schievelbusch T. , Neuhaus A. , David C. , Kock K. , Herrmann C. , Meyer H.E. , Wiese S. , Warscheid B. , Theiss C. , Erdmann R.
      J. Cell Sci.124:1759-1768(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TUBULIN
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