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Index > Protein center > PTGFR(Gene name) > Human
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  • PTGFR (Gene name),
  • Prostaglandin F2-alpha receptor (Protein name ),  PF2R_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    PTGFR;
    Protein name:
    Prostaglandin F2-alpha receptor(PGF receptor;PGF2-alpha receptor);
    Alternative:
    Prostanoid FP receptor;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    359
    Sequence:
    50:
    MSMNNSKQLV | SPAAALLSNT | TCQTENRLSV | FFSVIFMTVG | ILSNSLAIAI | 
    100:
    LMKAYQRFRQ | KSKASFLLLA | SGLVITDFFG | HLINGAIAVF | VYASDKEWIR | 
    150:
    FDQSNVLCSI | FGICMVFSGL | CPLLLGSVMA | IERCIGVTKP | IFHSTKITSK | 
    200:
    HVKMMLSGVC | LFAVFIALLP | ILGHRDYKIQ | ASRTWCFYNT | EDIKDWEDRF | 
    250:
    YLLLFSFLGL | LALGVSLLCN | AITGITLLRV | KFKSQQHRQG | RSHHLEMVIQ | 
    300:
    LLAIMCVSCI | CWSPFLVTMA | NIGINGNHSL | ETCETTLFAL | RMATWNQILD | 
    350:
    PWVYILLRKA | VLKNLYKLAS | QCCGVHVISL | HIWELSSIKN | SLKVAAISES | 
    359:
    PVAEKSAST
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human PGF receptor
    Cat.:
    E0749h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human PGF receptor
    Cat.:
    E0749m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human PGF receptor
    Cat.:
    E0749b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human PGF receptor
    Cat.:
    E0749r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human PGF receptor
    Cat.:
    U0749m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human PGF receptor
    Cat.:
    U0749r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human PGF receptor
    Cat.:
    U0749b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human PGF receptor
    Cat.:
    U0749h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human PGF receptor
    Cat.:
    P0749Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PGF receptor
    Cat.:
    P0749Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PGF receptor
    Polyclonal Antibody for Human PGF receptor
    Cat.:
    P0749Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human PGF receptor
    Monoclonal Antibody for Human PGF receptor
    Monoclonal Antibody for Human PGF receptor
    Monoclonal Antibody for Human PGF receptor
    Protein for Human PGF receptor
    Protein for Human PGF receptor
    Protein for Human PGF receptor
    Protein for Human PGF receptor

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    References
    1. 1.
      "Cloning and expression of a cDNA for the human prostanoid FP receptor."
      Abramovitz M. , Boie Y. , Nguyen T. , Rushmore T.H. , Bayne M.A. , Metters K.M. , Slipetz D.M. , Grygorczyk R.
      J. Biol. Chem.269:2632-2636(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Uterus.
    2. 2.
      "Functional characterization of the ocular prostaglandin f2alpha (PGF2alpha) receptor. Activation by the isoprostane, 12-iso-PGF2alpha."
      Kunapuli P. , Lawson J.A. , Rokach J. , FitzGerald G.A.
      J. Biol. Chem.272:27147-27154(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Ocular ciliary body.
    3. 3.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Kopatz S.A. , Aronstam R.S. , Sharma S.V.
      Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    4. 4.
      "Cloning and localization of hFP(S): a six-transmembrane mRNA splice variant of the human FP prostanoid receptor."
      Vielhauer G.A. , Fujino H. , Regan J.W.
      Arch. Biochem. Biophys.421:175-185(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);ALTERNATIVE SPLICING
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Trachea.
    6. 6.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    9. 9.
      "Structure of human prostaglandin F2alpha receptor gene."
      Nishizawa M. , Ito S.
      Submitted (2000-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-266
      tissue: Liver.
    10. 10.
      "Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes."
      Liang Y. , Woodward D.F. , Guzman V.M. , Li C. , Scott D.F. , Wang J.W. , Wheeler L.A. , Garst M.E. , Landsverk K. , Sachs G. , Krauss A.H. , Cornell C. , Martos J. , Pettit S. , Fliri H.
      Br. J. Pharmacol.154:1079-1093(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;ALTERNATIVE SPLICING;SUBUNIT
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