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Index > Protein center > PF4V1(Gene name) > Human
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  • PF4V1 (Gene name),
  • Platelet factor 4 variant (Protein name ),  PF4V_HUMAN from NCBI database.
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  • Gene name:
    PF4V1(CXCL4V1;SCYB4V1);
    Protein name:
    Platelet factor 4 variant;
    Alternative:
    CXCL4L1;C-X-C motif chemokine 4 variant;PF4var1;PF4alt;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Inhibitor of angiogenesis. Inhibitor of endothelial cell chemotaxis (in vitro).
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    104
    Sequence:
    50:
    MSSAARSRLT | RATRQEMLFL | ALLLLPVVVA | FARAEAEEDG | DLQCLCVKTT | 
    100:
    SQVRPRHITS | LEVIKAGPHC | PTAQLIATLK | NGRKICLDLQ | ALLYKKIIKE | 
    104:
    HLES
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    Pfam:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Platelet factor 4 variant
    CLIA Kit for Human Platelet factor 4 variant
    Polyclonal Antibody for Human Platelet factor 4 variant
    Monoclonal Antibody for Human Platelet factor 4 variant
    Protein for Human Platelet factor 4 variant

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    Linearity
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    References
    1. 1.
      "Identification and characterization of PF4var1, a human gene variant of platelet factor 4."
      Green C.J. , St Charles R. , Edwards B.F.P. , Johnson P.H.
      Mol. Cell. Biol.9:1445-1451(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Structural and functional comparison of the genes for human platelet factor 4 and PF4alt."
      Eisman R. , Surrey S. , Ramachandran B. , Schwartz E. , Poncz M.
      Blood76:336-344(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 27-104
    5. 5.
      "Platelets release CXCL4L1, a nonallelic variant of the chemokine platelet factor-4/CXCL4 and potent inhibitor of angiogenesis."
      Struyf S. , Burdick M.D. , Proost P. , Van Damme J. , Strieter R.M.
      Circ. Res.95:855-857(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 31-54;FUNCTION;MASS SPECTROMETRY
    6. 6.
      "Alternative C-terminal helix orientation alters chemokine function: Structure of the Anti-angiogenic Chemokine, CXCL4L1."
      Kuo J.H. , Chen Y.P. , Liu J.S. , Dubrac A. , Quemener C. , Prats H. , Bikfalvi A. , Wu W.G. , Sue S.C.
      J. Biol. Chem.288:13522-13533(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.08 ANGSTROMS) OF 35-104;DISULFIDE BONDS;HEPARIN-BINDING REGION;SUBUNIT
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