Protein name:
Alpha-type platelet-derived growth factor receptor (PDGF-R-alpha) ;
Alternative:
Alpha-type platelet-derived growth factor receptor ;CD140 antigen-like family member A ;Platelet-derived growth factor alpha receptor ;CD140 antigen-like family member A ;
CD:
CD140a ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer, and heterodimer with PDGFRB. Interacts with the SH2 domain of SHB via phosphorylated Tyr-720. Interacts with the SH2 domain of SHF via phosphorylated Tyr-720.
Function:
Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MGTSHQVFLV | LSCLLTGPGL | ISCQLLLPSI | LPNENEKIVQ | LNSSFSLRCV |
100:
GESEVSWQHP | MSEEDDPNVE | IRSEENNSGL | FVTVLEVVNA | SAAHTGWYTC |
150:
YYNHTQTDES | EIEGRHIYIY | VPDPDMAFVP | LGMTDSLVIV | EEDDSAIIPC |
200:
RTTDPETQVT | LHNNGRLVPA | SYDSRQGFNG | TFSVGPYICE | ATVKGRTFKT |
250:
SEFNVYALKA | TSELNLEMDA | RQTVYKAGET | IVVTCAVFNN | EVVDLQWTYP |
300:
GEVRNKGITM | LEEIKLPSIK | LVYTLTVPKA | TVKDSGEYEC | AARQATKEVK |
350:
EMKRVTISVH | EKGFVEIEPT | FGQLEAVNLH | EVREFVVEVQ | AYPTPRISWL |
400:
KDNLTLIENL | TEITTDVQKS | QETRYQSKLK | LIRAKEEDSG | HYTIIVQNED |
450:
DVKSYTFELS | TLVPASILDL | VDDHHGSGGG | QTVRCTAEGT | PLPEIDWMIC |
500:
KHIKKCNNDT | SWTVLASNVS | NIITELPRRG | RSTVEGRVSF | AKVEETIAVR |
550:
CLAKNNLSVV | ARELKLVAPT | LRSELTVAAA | VLVLLVIVIV | SLIVLVVIWK |
600:
QKPRYEIRWR | VIESISPDGH | EYIYVDPMQL | PYDSRWEFPR | DGLVLGRILG |
650:
SGAFGKVVEG | TAYGLSRSQP | VMKVAVKMLK | PTARSSEKQA | LMSELKIMTH |
700:
LGPHLNIVNL | LGACTKSGPI | YIITEYCFYG | DLVNYLHKNR | DSFMSQHPEK |
750:
PKKDLDIFGL | NPADESTRSY | VILSFENNGD | YMDMKQADTT | QYVPMLERKE |
800:
VSKYSDIQRS | LYDRPASYKK | KSMLDSEVKN | LLSDDDSEGL | TLLDLLSFTY |
850:
QVARGMEFLA | SKNCVHRDLA | ARNVLLAQGK | IVKICDFGLA | RDIMHDSNYV |
900:
SKGSTFLPVK | WMAPESIFDN | LYTTLSDVWS | YGILLWEIFS | LGGTPYPGMM |
950:
VDSTFYNKIK | SGYRMAKPDH | ATSEVYEIMV | QCWNSEPEKR | PSFYHLSEIV |
1000:
ENLLPGQYKK | SYEKIHLDFL | KSDHPAVARM | RVDSDNAYIG | VTYKNEEDKL |
1050:
KDWEGGLDEQ | RLSADSGYII | PLPDIDPVPE | EEDLGKRNRH | SSQTSEESAI |
1089:
ETGSSSSTFI | KREDETIEDI | DMMDDIGIDS | SDLVEDSFL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Chicken
Mouse
ELISA Kit for Mouse PDGF-R-alpha
ELISA Kit for Mouse PDGF-R-alpha
ELISA Kit for Mouse PDGF-R-alpha
ELISA Kit for Mouse PDGF-R-alpha
CLIA Kit for Mouse PDGF-R-alpha
CLIA Kit for Mouse PDGF-R-alpha
CLIA Kit for Mouse PDGF-R-alpha
CLIA Kit for Mouse PDGF-R-alpha
Polyclonal Antibody for Mouse PDGF-R-alpha
Polyclonal Antibody for Mouse PDGF-R-alpha
Polyclonal Antibody for Mouse PDGF-R-alpha
Polyclonal Antibody for Mouse PDGF-R-alpha
Monoclonal Antibody for Mouse PDGF-R-alpha
Monoclonal Antibody for Mouse PDGF-R-alpha
Monoclonal Antibody for Mouse PDGF-R-alpha
Monoclonal Antibody for Mouse PDGF-R-alpha
Protein for Mouse PDGF-R-alpha
Protein for Mouse PDGF-R-alpha
Protein for Mouse PDGF-R-alpha
Protein for Mouse PDGF-R-alpha
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6J .
tissue :
Cerebellum .
tissue :
Colon .
tissue :
Embryonic head .
tissue :
Placenta .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6 .
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE;FUNCTION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE;FUNCTION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SHB
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON FUNCTION;DISRUPTION PHENOTYPE
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
11.
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Christensen S.T.
Cell. Physiol. Biochem.25:279-292(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION