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Index > Protein center > Phlda1(Gene name) > Mouse
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  • Phlda1 (Gene name),
  • Pleckstrin homology-like domain family A member 1 (Protein name ),  PHLA1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Phlda1(Tdag51);
    Protein name:
    Pleckstrin homology-like domain family A member 1;
    Alternative:
    T-cell death-associated gene 51 protein;Proline- and glutamine-rich protein(PQ-rich protein;PQR protein);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with RPL14, EIF3S7 and PABPC4.
    Function:
    Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. Required for TCR-induced apoptosis and expression of TNFRSF6/FAS in a T-cell hybridoma cell line. May be involved in translational regulation.
    Subcellular Location:
    Cytoplasm Cytoplasmic vesicle membrane Nucleus nucleolus Colocalizes with intracellular vesicles.
    Protein Attributes:
    Sequence length:
    405
    Sequence:
    50:
    MRRTPAAERL | SELGFPPRRG | RQEPPFPLGV | TRGWGGWPIE | KRREGPRPVP | 
    100:
    FSERSPEDGR | EQPAHGSGIL | WRVRTRLSLC | RDPEPPPPPP | PLCLLRVSLL | 
    150:
    CALRAGGRGS | RWGEDGAGLL | LLPPAGASGS | LKAERSSSTP | YAGRMLENSG | 
    200:
    CKALKEGVLE | KRSDGLLQLW | KKKCCILTEE | GLLLIPPKQL | QQQQQQQQPG | 
    250:
    QGTAEPSQPS | GPTVASLEPP | VKLKELHFSN | MKTVDCVERK | GKYMYFTVVM | 
    300:
    TEGKEIDFRC | PQDQGWNAEI | TLQMVQYKNR | QAILAVKSTR | QKQQHLVQQQ | 
    350:
    PPQTQQIQPQ | PQPQIQPQPQ | PQIQPQPQPQ | PQPQPQPQPQ | PQPQQLHSYP | 
    400:
    HPHPHPYSHP | HQHPHPHPHP | HPHPHPHPYQ | LQHAHQPLHS | QPQGHRLLRS | 
    405:
    TSNSA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Pleckstrin homology-like domain family A member 1
    ELISA Kit for Mouse Pleckstrin homology-like domain family A member 1
    ELISA Kit for Mouse Pleckstrin homology-like domain family A member 1
    CLIA Kit for Mouse Pleckstrin homology-like domain family A member 1
    CLIA Kit for Mouse Pleckstrin homology-like domain family A member 1
    CLIA Kit for Mouse Pleckstrin homology-like domain family A member 1
    Polyclonal Antibody for Mouse Pleckstrin homology-like domain family A member 1
    Polyclonal Antibody for Mouse Pleckstrin homology-like domain family A member 1
    Polyclonal Antibody for Mouse Pleckstrin homology-like domain family A member 1
    Monoclonal Antibody for Mouse Pleckstrin homology-like domain family A member 1
    Monoclonal Antibody for Mouse Pleckstrin homology-like domain family A member 1
    Monoclonal Antibody for Mouse Pleckstrin homology-like domain family A member 1
    Protein for Mouse Pleckstrin homology-like domain family A member 1
    Protein for Mouse Pleckstrin homology-like domain family A member 1
    Protein for Mouse Pleckstrin homology-like domain family A member 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death."
      Park C.G. , Lee S.Y. , Kandala G. , Lee S.Y. , Choi Y.
      Immunity4:583-591(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 50-405
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 107-405
      strain: 129.
      tissue: Mammary tumor.
    4. 4.
      "A proline- and glutamine-rich protein promotes apoptosis in neuronal cells."
      Gomes I. , Xiong W. , Miki T. , Rosner M.R.
      J. Neurochem.73:612-622(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "A novel pleckstrin homology-related gene family defined by Ipl/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprinting."
      Frank D. , Mendelsohn C.L. , Ciccone E. , Svensson K. , Ohlsson R. , Tycko B.
      Mamm. Genome10:1150-1159(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    6. 6.
      "TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia."
      Hossain G.S. , van Thienen J.V. , Werstuck G.H. , Zhou J. , Sood S.K. , Dickhout J.G. , de Koning A.B. , Tang D. , Wu D. , Falk E. , Poddar R. , Jacobsen D.W. , Zhang K. , Kaufman R.J. , Austin R.C.
      J. Biol. Chem.278:30317-30327(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    7. 7.
      "TDAG51 mediates the effects of insulin-like growth factor I (IGF-I) on cell survival."
      Toyoshima Y. , Karas M. , Yakar S. , Dupont J. , Helman L. , LeRoith D.
      J. Biol. Chem.279:25898-25904(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
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