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Index > Protein center > PIGU(Gene name) > Human
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  • PIGU (Gene name),
  • Phosphatidylinositol glycan anchor biosynthesis class U protein (Protein name ),  PIGU_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    PIGU(PSEC0205;UNQ3055/PRO9875;CDC91L1);
    Protein name:
    Phosphatidylinositol glycan anchor biosynthesis class U protein;
    Alternative:
    GPI transamidase component PIG-U;Cell division cycle protein 91-like 1(Protein CDC91-like 1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Forms a complex with PIGK/GPI8, PIGS, PIGT and GPAA1/GAA1.
    Function:
    Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    435
    Sequence:
    50:
    MAAPLVLVLV | VAVTVRAALF | RSSLAEFISE | RVEVVSPLSS | WKRVVEGLSL | 
    100:
    LDLGVSPYSG | AVFHETPLII | YLFHFLIDYA | ELVFMITDAL | TAIALYFAIQ | 
    150:
    DFNKVVFKKQ | KLLLELDQYA | PDVAELIRTP | MEMRYIPLKV | ALFYLLNPYT | 
    200:
    ILSCVAKSTC | AINNTLIAFF | ILTTIKGSAF | LSAIFLALAT | YQSLYPLTLF | 
    250:
    VPGLLYLLQR | QYIPVKMKSK | AFWIFSWEYA | MMYVGSLVVI | ICLSFFLLSS | 
    300:
    WDFIPAVYGF | ILSVPDLTPN | IGLFWYFFAE | MFEHFSLFFV | CVFQINVFFY | 
    350:
    TIPLAIKLKE | HPIFFMFIQI | AVIAIFKSYP | TVGDVALYMA | FFPVWNHLYR | 
    400:
    FLRNIFVLTC | IIIVCSLLFP | VLWHLWIYAG | SANSNFFYAI | TLTFNVGQIL | 
    435:
    LISDYFYAFL | RREYYLTHGL | YLTAKDGTEA | MLVLK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    ELISA Kit for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    ELISA Kit for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    CLIA Kit for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    CLIA Kit for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    CLIA Kit for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    Polyclonal Antibody for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    Polyclonal Antibody for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    Polyclonal Antibody for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    Monoclonal Antibody for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    Monoclonal Antibody for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    Monoclonal Antibody for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    Protein for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    Protein for Human Phosphatidylinositol glycan anchor biosynthesis class U protein
    Protein for Human Phosphatidylinositol glycan anchor biosynthesis class U protein

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins."
      Hong Y. , Ohishi K. , Kang J.Y. , Tanaka S. , Inoue N. , Nishimura J. , Maeda Y. , Kinoshita T.
      Mol. Biol. Cell14:1780-1789(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 2-8;FUNCTION;SUBUNIT
      tissue: Embryo.
    2. 2.
      "PIG-U is a novel oncogene in human bladder cancer."
      Guo Z. , Wu G. , Sidransky D. , Trink B.
      Submitted (2003-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      Lin L. , Yu R. , Ke R. , Li H. , Zhou G. , Shen C. , Zheng G. , Zhong G. , Li M. , Xiao W. , Yang S.
      Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    4. 4.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
      Otsuki T. , Ota T. , Nishikawa T. , Hayashi K. , Suzuki Y. , Yamamoto J. , Wakamatsu A. , Kimura K. , Sakamoto K. , Hatano N. , Kawai Y. , Ishii S. , Saito K. , Kojima S. , Sugiyama T. , Ono T. , Okano K. , Yoshikawa Y. , more...
      DNA Res.12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Embryo.
    6. 6.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
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