Pitpnm1 ELISA Kit for Mouse(Mus musculus) | EIAab.comPitpnm1 ELISA Kit for Mouse(Mus musculus)

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Pitpnm1 (Gene name),

Membrane-associated phosphatidylinositol transfer protein 1 (Protein name ), PITM1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Pitpnm1(Dres9;Mpt1;Nir2;Pitpnm);

Protein name:

Membrane-associated phosphatidylinositol transfer protein 1;

Alternative:

Mpt-1;Drosophila retinal degeneration B homolog 1(RdgB1);Pyk2 N-terminal domain-interacting receptor 2(NIR-2);Phosphatidylinositol transfer protein, membrane-associated 1(PITPnm 1);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with PTK2B via its C-terminus. Interacts with RHOA. Has higher affinity for the inactive, GDP-bound form of RHOA. The CDK1-phosphorylated form interacts with PLK1. Interacts with VAPB and PIK4CA.

Function:

Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.

Subcellular Location:

Cytoplasm Golgi apparatus Golgi stack membrane Peripheral membrane protein Endoplasmic reticulum membrane Peripheral membrane protein Lipid droplet Cleavage furrow Midbody Peripheral membrane protein associated with Golgi stacks in interphase cells. A minor proportion is associated with the endoplasmic reticulum. Associated with lipid droplets. Dissociates from the Golgi early on in mitosis and localizes to the cleavage furrow and midbody during cytokinesis.

Protein Attributes:

Sequence length:

1243

Sequence:

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1243:

RKQSQLLRSR | GPSQVDREGP | GTPPTTLARG | KTRSISLKLD | SEE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:18739

String:

O35954

SMR:

O35954

UniGene:

Mm.1860

Pfam:

PF02862

STRING:

10090.ENSMUSP00000097599

Uniprot:

O35954

FOR

ELISA Kit for Mouse Membrane-associated phosphatidylinositol transfer protein 1

CLIA Kit for Mouse Membrane-associated phosphatidylinositol transfer protein 1

Polyclonal Antibody for Mouse Membrane-associated phosphatidylinositol transfer protein 1

Monoclonal Antibody for Mouse Membrane-associated phosphatidylinositol transfer protein 1

Protein for Mouse Membrane-associated phosphatidylinositol transfer protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and characterization of mammalian homologues of the Drosophila retinal degeneration B gene."
Aikawa Y. , Hara H. , Watanabe T.
Biochem. Biophys. Res. Commun.236:559-564(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
strain: BALB/c.
tissue: Brain.
2.

"A mammalian homologue of the Drosophila retinal degeneration B gene: implications for the evolution of phototransduction mechanisms."
Rubboli F. , Bulfone A. , Bogni S. , Marchitiello A. , Zollo M. , Borsani G. , Ballabio A. , Banfi S.
Genes Funct.1:205-213(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
tissue: Retina.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.
tissue: Eye.
4.

"Involvement of PITPnm, a mammalian homologue of Drosophila rdgB, in phosphoinositide synthesis on Golgi membranes."
Aikawa Y. , Kuraoka A. , Kondo H. , Kawabuchi M. , Watanabe T.
J. Biol. Chem.274:20569-20577(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH PIK4CA

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