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Index > Protein center > PJA1(Gene name) > Human
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  • PJA1 (Gene name),
  • E3 ubiquitin-protein ligase Praja-1 (Protein name ),  PJA1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PJA1(RNF70);
    Protein name:
    E3 ubiquitin-protein ligase Praja-1(Praja1);
    Alternative:
    RING finger protein 70;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds ubiquitin-conjugating enzymes (E2s). In vitro, interacts with the ubiquitin-conjugating enzyme, UBE2D2.
    Function:
    Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    643
    Sequence:
    50:
    MGQESSKPVW | PNPTGGYQSN | TGRRYGRRHA | YVSFRPPTSQ | RERIASQRKT | 
    100:
    NSEVPMHRSA | PSQTTKRSRS | PFSTTRRSWD | DSESSGTNLN | IDNEDYSRYP | 
    150:
    PREYRASGSR | RGMAYGHIDS | YGADDSEEEG | AGPVERPPVR | GKTGKFKDDK | 
    200:
    LYDPEKGARS | LAGPPPHFSS | FSRDVREERD | KLDPVPAARC | SASRADFLPQ | 
    250:
    SSVASQSSSE | GKLATKGDSS | ERERREQNLP | ARPSRAPVSI | CGGGENTSKS | 
    300:
    AEEPVVRPKI | RNLASPNCVK | PKIFFDTDDD | DDMPHSTSRW | RDTANDNEGH | 
    350:
    SDGLARRGRG | ESSSGYPEPK | YPEDKREARS | DQVKPEKVPR | RRRTMADPDF | 
    400:
    WTHSDDYYKY | CDEDSDSDKE | WIAALRRKYR | SREQTLSSSG | ESWETLPGKE | 
    450:
    EREPPQAKVS | ASTGTSPGPG | ASASAGAGAG | ASAGSNGSNY | LEEVREPSLQ | 
    500:
    EEQASLEEGE | IPWLQYHEND | SSSEGDNDSG | HELMQPGVFM | LDGNNNLEDD | 
    550:
    SSVSEDLEVD | WSLFDGFADG | LGVAEAISYV | DPQFLTYMAL | EERLAQAMET | 
    600:
    ALAHLESLAV | DVEVANPPAS | KESIDALPEI | LVTEDHGAVG | QEMCCPICCS | 
    643:
    EYVKGEVATE | LPCHHYFHKP | CVSIWLQKSG | TCPVCRCMFP | PPL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    KEGG:
    MIM:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Praja1
    ELISA Kit for Human Praja1
    CLIA Kit for Human Praja1
    CLIA Kit for Human Praja1
    Polyclonal Antibody for Human Praja1
    Polyclonal Antibody for Human Praja1
    Monoclonal Antibody for Human Praja1
    Monoclonal Antibody for Human Praja1
    Protein for Human Praja1
    Protein for Human Praja1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "PJA1, encoding a RING-H2 finger ubiquitin ligase, is a novel human X chromosome gene abundantly expressed in brain."
      Yu P. , Chen Y. , Tagle D.A. , Cai T.
      Genomics79:869-874(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH UBE2D2
      tissue: Brain.
    2. 2.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS ASN-432 AND ASP-606
      tissue: Brain.
      tissue: Kidney.
      tissue: Uterus.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 282-643 (ISOFORM 1)
      tissue: Embryo.
    6. 6.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-277;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    7. 7.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-277;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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