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Index > Protein center > PLEKHM1(Gene name) > Human
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  • PLEKHM1 (Gene name),
  • Pleckstrin homology domain-containing family M member 1 (Protein name ),  PKHM1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PLEKHM1(KIAA0356);
    Protein name:
    Pleckstrin homology domain-containing family M member 1(PH domain-containing family M member 1);
    Alternative:
    162 kDa adapter protein(AP162);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    In colon carcinoma and breast carcinoma cells, it interacts with sialyl-lex-positive protein.
    Function:
    Involved in vesicular transport in the osteoclast (By similarity). May have a role in sialyl-lex-mediated transduction of apoptotic signals.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    1056
    Sequence:
    50:
    MLSVVENGLD | PQAAIPVIKK | KLVGSVKALQ | KQYVSLDTVV | TSEDGDANTM | 
    100:
    CSALEAVFIH | GLHAKHIRAE | AGGKRKKSAH | QKPLPQPVFW | PLLKAVTHKH | 
    150:
    IISELEHLTF | VNTDVGRCRA | WLRLALNDGL | MECYLKLLLQ | EQARLHEYYQ | 
    200:
    PTALLRDAEE | GEFLLSFLQG | LTSLSFELSY | KSAILNEWTL | TPLALSGLCP | 
    250:
    LSELDPLSTS | GAELQRKESL | DSISHSSGSE | DIEVHHSGHK | IRRNQKLTAS | 
    300:
    SLSLDTASSS | QLSCSLNSDS | CLLQENGSKS | PDHCEEPMSC | DSDLGTANAE | 
    350:
    DSDRSLQEVL | LEFSKAQVNS | VPTNGLSQET | EIPTPQASLS | LHGLNTSTYL | 
    400:
    HCEAPAEPLP | AQAASGTQDG | VHVQEPRPQA | PSPLDLQQPV | ESTSGQQPSS | 
    450:
    TVSETAREVG | QGNGLQKAQA | HDGAGLKLVV | SSPTSPKNKS | WISEDDFYRP | 
    500:
    SREQPLESAS | DHPIASYRGT | PGSRPGLHRH | FSQEPRKNCS | LGALDQACVP | 
    550:
    SPGRRQAQAA | PSQGHKSFRV | VHRRQMGLSN | PFRGLMKLGT | VERRGAMGIW | 
    600:
    KELFCELSPL | EFRLYLSNEE | HTCVENCSLL | RCESVGPAHS | DGRFELVFSG | 
    650:
    KKLALRASSQ | DEAEDWLDRV | REALQKVRPQ | QEDEWVNVQY | PDQPEEPPEA | 
    700:
    PQGCLSPSDL | LSEPAALQGT | QFDWSSAQVP | EPDAIKESLL | YLYMDRTWMP | 
    750:
    YIFSLSLEAL | KCFRIRNNEK | MLSDSHGVET | IRDILPDTSL | GGPSFFKIIT | 
    800:
    AKAVLKLQAG | NAEEAALWRD | LVRKVLASYL | ETAEEAVTLG | GSLDENCQEV | 
    850:
    LKFATRENGF | LLQYLVAIPM | EKGLDSQGCF | CAGCSRQIGF | SFVRPKLCAF | 
    900:
    SGLYYCDICH | QDDASVIPAR | IIHNWDLTKR | PICRQALKFL | TQIRAQPLIN | 
    950:
    LQMVNASLYE | HVERMHLIGR | RREQLKLLGD | YLGLCRSGAL | KELSKRLNHR | 
    1000:
    NYLLESPHRF | SVADLQQIAD | GVYEGFLKAL | IEFASQHVYH | CDLCTQRGFI | 
    1050:
    CQICQHHDII | FPFEFDTTVR | CAECKTVFHQ | SCQAVVKKGC | PRCARRRKYQ | 
    1056:
    EQNIFA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    UniGene:
    Pfam:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human PH domain-containing family M member 1
    ELISA Kit for Human PH domain-containing family M member 1
    ELISA Kit for Human PH domain-containing family M member 1
    CLIA Kit for Human PH domain-containing family M member 1
    CLIA Kit for Human PH domain-containing family M member 1
    CLIA Kit for Human PH domain-containing family M member 1
    Polyclonal Antibody for Human PH domain-containing family M member 1
    Polyclonal Antibody for Human PH domain-containing family M member 1
    Polyclonal Antibody for Human PH domain-containing family M member 1
    Monoclonal Antibody for Human PH domain-containing family M member 1
    Monoclonal Antibody for Human PH domain-containing family M member 1
    Monoclonal Antibody for Human PH domain-containing family M member 1
    Protein for Human PH domain-containing family M member 1
    Protein for Human PH domain-containing family M member 1
    Protein for Human PH domain-containing family M member 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Nakajima D. , Ohira M. , Seki N. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.4:141-150(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];TISSUE SPECIFICITY
      tissue: Brain.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Uterus.
    3. 3.
      "Novel adapter protein AP162 connects a sialyl-Le(x)-positive mucin with an apoptotic signal transduction pathway."
      Hartel-Schenk S. , Gratchev A. , Hanski M.-L. , Ogorek D. , Trendelenburg G. , Hummel M. , Hoepfner M. , Scheruebl H. , Zeitz M. , Hanski C.
      Glycoconj. J.18:915-923(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 82-1056;TISSUE SPECIFICITY;FUNCTION;INTERACTION WITH SIALYL-LEX POSITIVE MUCIN
      tissue: Colon carcinoma.
    4. 4.
      "The nucleotide sequence of a long cDNA clone isolated from human spleen."
      Jikuya H. , Takano J. , Nomura N. , Kikuno R. , Nagase T. , Ohara O.
      Submitted (2002-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 425-1056
      tissue: Spleen.
    5. 5.
      The European IMAGE consortium
      Submitted (2000-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 528-832
    6. 6.
      "Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans."
      van Wesenbeeck L. , Odgren P.R. , Coxon F.P. , Frattini A. , Moens P. , Perdu B. , MacKay C.A. , Van Hul E. , Timmermanns J.-P. , Vanhoenacker F. , Jacobs R. , Peruzzi B. , Teti A. , Helfrich M.H. , Rogers M.J. , Villa A. , Van Hul W.
      J. Clin. Invest.117:919-930(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN OPTB6
    7. 7.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
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