Gene name:
PLEKHM1 (KIAA0356) ;
Protein name:
Pleckstrin homology domain-containing family M member 1 (PH domain-containing family M member 1) ;
Alternative:
162 kDa adapter protein (AP162) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
In colon carcinoma and breast carcinoma cells, it interacts with sialyl-lex-positive protein.
Function:
Involved in vesicular transport in the osteoclast (By similarity). May have a role in sialyl-lex-mediated transduction of apoptotic signals.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MLSVVENGLD | PQAAIPVIKK | KLVGSVKALQ | KQYVSLDTVV | TSEDGDANTM |
100:
CSALEAVFIH | GLHAKHIRAE | AGGKRKKSAH | QKPLPQPVFW | PLLKAVTHKH |
150:
IISELEHLTF | VNTDVGRCRA | WLRLALNDGL | MECYLKLLLQ | EQARLHEYYQ |
200:
PTALLRDAEE | GEFLLSFLQG | LTSLSFELSY | KSAILNEWTL | TPLALSGLCP |
250:
LSELDPLSTS | GAELQRKESL | DSISHSSGSE | DIEVHHSGHK | IRRNQKLTAS |
300:
SLSLDTASSS | QLSCSLNSDS | CLLQENGSKS | PDHCEEPMSC | DSDLGTANAE |
350:
DSDRSLQEVL | LEFSKAQVNS | VPTNGLSQET | EIPTPQASLS | LHGLNTSTYL |
400:
HCEAPAEPLP | AQAASGTQDG | VHVQEPRPQA | PSPLDLQQPV | ESTSGQQPSS |
450:
TVSETAREVG | QGNGLQKAQA | HDGAGLKLVV | SSPTSPKNKS | WISEDDFYRP |
500:
SREQPLESAS | DHPIASYRGT | PGSRPGLHRH | FSQEPRKNCS | LGALDQACVP |
550:
SPGRRQAQAA | PSQGHKSFRV | VHRRQMGLSN | PFRGLMKLGT | VERRGAMGIW |
600:
KELFCELSPL | EFRLYLSNEE | HTCVENCSLL | RCESVGPAHS | DGRFELVFSG |
650:
KKLALRASSQ | DEAEDWLDRV | REALQKVRPQ | QEDEWVNVQY | PDQPEEPPEA |
700:
PQGCLSPSDL | LSEPAALQGT | QFDWSSAQVP | EPDAIKESLL | YLYMDRTWMP |
750:
YIFSLSLEAL | KCFRIRNNEK | MLSDSHGVET | IRDILPDTSL | GGPSFFKIIT |
800:
AKAVLKLQAG | NAEEAALWRD | LVRKVLASYL | ETAEEAVTLG | GSLDENCQEV |
850:
LKFATRENGF | LLQYLVAIPM | EKGLDSQGCF | CAGCSRQIGF | SFVRPKLCAF |
900:
SGLYYCDICH | QDDASVIPAR | IIHNWDLTKR | PICRQALKFL | TQIRAQPLIN |
950:
LQMVNASLYE | HVERMHLIGR | RREQLKLLGD | YLGLCRSGAL | KELSKRLNHR |
1000:
NYLLESPHRF | SVADLQQIAD | GVYEGFLKAL | IEFASQHVYH | CDLCTQRGFI |
1050:
CQICQHHDII | FPFEFDTTVR | CAECKTVFHQ | SCQAVVKKGC | PRCARRRKYQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
ELISA Kit for Human PH domain-containing family M member 1
ELISA Kit for Human PH domain-containing family M member 1
ELISA Kit for Human PH domain-containing family M member 1
CLIA Kit for Human PH domain-containing family M member 1
CLIA Kit for Human PH domain-containing family M member 1
CLIA Kit for Human PH domain-containing family M member 1
Polyclonal Antibody for Human PH domain-containing family M member 1
Polyclonal Antibody for Human PH domain-containing family M member 1
Polyclonal Antibody for Human PH domain-containing family M member 1
Monoclonal Antibody for Human PH domain-containing family M member 1
Monoclonal Antibody for Human PH domain-containing family M member 1
Monoclonal Antibody for Human PH domain-containing family M member 1
Protein for Human PH domain-containing family M member 1
Protein for Human PH domain-containing family M member 1
Protein for Human PH domain-containing family M member 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];TISSUE SPECIFICITY
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Uterus .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 82-1056;TISSUE SPECIFICITY;FUNCTION;INTERACTION WITH SIALYL-LEX POSITIVE MUCIN
tissue :
Colon carcinoma .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 425-1056
tissue :
Spleen .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 528-832
6.
"Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans."
van Wesenbeeck L.
,
Odgren P.R.
,
Coxon F.P.
,
Frattini A.
,
Moens P.
,
Perdu B.
,
MacKay C.A.
,
Van Hul E.
,
Timmermanns J.-P.
,
Vanhoenacker F.
,
Jacobs R.
,
Peruzzi B.
,
Teti A.
,
Helfrich M.H.
,
Rogers M.J.
,
Villa A.
,
Van Hul W.
J. Clin. Invest.117:919-930(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN OPTB6
7.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V.
,
Vermeulen M.
,
Santamaria A.
,
Kumar C.
,
Miller M.L.
,
Jensen L.J.
,
Gnad F.
,
Cox J.
,
Jensen T.S.
,
Nigg E.A.
,
Brunak S.
,
Mann M.
Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .