Jup ELISA Kit for Pig(Sus scrofa) | EIAab.comJup ELISA Kit for Pig(Sus scrofa)

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Index > Protein center > Jup(Gene name) > Pig

Jup (Gene name),

Junction plakoglobin (Protein name ), PLAK_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Jup;

Protein name:

Junction plakoglobin;

Alternative:

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Homodimer. Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1 and gamma-catenin/JUP, and possibly alpha-catenin/CTNNA1; the complex is located to adherens junctions. The stable association of CTNNA1 is controversial as CTNNA1 was shown not to bind to F-actin when assembled in the complex. Interacts with MUC1. Interacts with CAV1. Interacts with PTPRJ.

Function:

Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.

Subcellular Location:

Cell junction adherens junction Cell junction desmosome Cytoplasm cytoskeleton Membrane Peripheral membrane protein Cytoplasmic in a soluble and membrane-associated form.

Protein Attributes:

Sequence length:

745

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

745:

YRPMYSSDVP | LDPLEMHMDM | DGDYPMDTYS | DGLRPPYPAA | DHMLA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9823.ENSSSCP00000018469

Pfam:

PF00514

SMR:

Q8WNW3

UniGene:

Ssc.42011

String:

Q8WNW3

KEGG:

ssc:397592

Uniprot:

Q8WNW3

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ELISA Kit for Pig Junction plakoglobin

Cat.:

E15107h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Pig Junction plakoglobin

MSDS:

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ELISA Kit for Pig Junction plakoglobin

MSDS:

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ELISA Kit for Pig Junction plakoglobin

MSDS:

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ELISA Kit for Pig Junction plakoglobin

MSDS:

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CLIA Kit for Pig Junction plakoglobin

MSDS:

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CLIA Kit for Pig Junction plakoglobin

Cat.:

U15107h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig Junction plakoglobin

MSDS:

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CLIA Kit for Pig Junction plakoglobin

MSDS:

Please sign in first.

CLIA Kit for Pig Junction plakoglobin

MSDS:

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Polyclonal Antibody for Pig Junction plakoglobin

Monoclonal Antibody for Pig Junction plakoglobin

Protein for Pig Junction plakoglobin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Transcriptional upregulation of p27Kip1 during contact-induced growth arrest in endothelial cells."
Hirano M. , Hirano K. , Nishimura J. , Kanaide H.
Submitted (2000-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Aortic endothelium.

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