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Index > Protein center > PLCD1(Gene name) > Human
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  • PLCD1 (Gene name),
  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 (Protein name ),  PLCD1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PLCD1;
    Protein name:
    1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1;
    Alternative:
    Phospholipase C-III(PLC-III);Phosphoinositide phospholipase C-delta-1;Phospholipase C-delta-1(PLC-delta-1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Essential for trophoblast and placental development.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    756
    Sequence:
    50:
    MDSGRDFLTL | HGLQDDEDLQ | ALLKGSQLLK | VKSSSWRRER | FYKLQEDCKT | 
    100:
    IWQESRKVMR | TPESQLFSIE | DIQEVRMGHR | TEGLEKFARD | VPEDRCFSIV | 
    150:
    FKDQRNTLDL | IAPSPADAQH | WVLGLHKIIH | HSGSMDQRQK | LQHWIHSCLR | 
    200:
    KADKNKDNKM | SFKELQNFLK | ELNIQVDDSY | ARKIFRECDH | SQTDSLEDEE | 
    250:
    IEAFYKMLTQ | RVEIDRTFAE | AAGSGETLSV | DQLVTFLQHQ | QREEAAGPAL | 
    300:
    ALSLIERYEP | SETAKAQRQM | TKDGFLMYLL | SADGSAFSLA | HRRVYQDMGQ | 
    350:
    PLSHYLVSSS | HNTYLLEDQL | AGPSSTEAYI | RALCKGCRCL | ELDCWDGPNQ | 
    400:
    EPIIYHGYTF | TSKILFCDVL | RAIRDYAFKA | SPYPVILSLE | NHCTLEQQRV | 
    450:
    MARHLHAILG | PMLLNRPLDG | VTNSLPSPEQ | LKGKILLKGK | KLGGLLPPGG | 
    500:
    EGGPEATVVS | DEDEAAEMED | EAVRSRVQHK | PKEDKLRLAQ | ELSDMVIYCK | 
    550:
    SVHFGGFSSP | GTPGQAFYEM | ASFSENRALR | LLQESGNGFV | RHNVGHLSRI | 
    600:
    YPAGWRTDSS | NYSPVEMWNG | GCQIVALNFQ | TPGPEMDVYQ | GRFQDNGACG | 
    650:
    YVLKPAFLRD | PNGTFNPRAL | AQGPWWARKR | LNIRVISGQQ | LPKVNKNKNS | 
    700:
    IVDPKVTVEI | HGVSRDVASR | QTAVITNNGF | NPWWDTEFAF | EVVVPDLALI | 
    750:
    RFLVEDYDAS | SKNDFIGQST | IPLNSLKQGY | RHVHLMSKNG | DQHPSATLFV | 
    756:
    KISLQD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    UniGene:
    SMR:
    Pfam:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    ELISA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    ELISA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    ELISA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    CLIA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    CLIA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    CLIA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    CLIA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Polyclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Polyclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Polyclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Polyclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Monoclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Monoclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Monoclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Monoclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Protein for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Protein for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Protein for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    Protein for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1

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    References
    1. 1.
      "Cloning and identification of amino acid residues of human phospholipase C delta 1 essential for catalysis."
      Cheng H.F. , Jiang M.J. , Chen C.L. , Liu S.M. , Wong L.P. , Lomasney J.W. , King K.
      J. Biol. Chem.270:5495-5505(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Aorta.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Amygdala.
    3. 3.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    6. 6.
      "Hereditary leukonychia, or porcelain nails, resulting from mutations in PLCD1."
      Kiuru M. , Kurban M. , Itoh M. , Petukhova L. , Shimomura Y. , Wajid M. , Christiano A.M.
      Am. J. Hum. Genet.88:839-844(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NDNC3 ARG-209 AND THR-574
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