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Index > Protein center > PLCZ1(Gene name) > Chicken
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  • PLCZ1 (Gene name),
  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 (Protein name ),  PLCZ1_CHICK from NCBI database.
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  • Gene name:
    PLCZ1;
    Protein name:
    1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1;
    Alternative:
    Phospholipase C-zeta-1(PLC-zeta-1);Phosphoinositide phospholipase C-zeta-1;
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Interacts via its C2 domain with PtdIns(3)P and, to a lesser extent, PtdIns(5)P in vitro.
    Function:
    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
    Subcellular Location:
    Nucleus Cytoplasm perinuclear region Exhibits alternative cytoplasmic/nuclear localization during development. Translocates from the pronucleus into cytoplasm upon nuclear envelope breakdown for mitosis and localizes again to the pronucleus at interphase following meiosis and mitosis.
    Protein Attributes:
    Sequence length:
    637
    Sequence:
    50:
    MEENRWFLNI | IQDGFMNGKI | DFDSTVKLLE | KLHMPFNLAH | VKHVFKKTVD | 
    100:
    KRKIHTINIE | DFRAIYRAIV | HRNEFHEIFC | AYSENRKNLA | DTELTAFLKK | 
    150:
    EQFKTEGAET | TALEVILKYE | PIDEVRKRRQ | LSFEGFIRYM | SSEDCTIFKK | 
    200:
    EHRTVYQDMN | HPLCDYFISS | SHNTYLVSDQ | LIGPSDLNGY | ISALLKGCRC | 
    250:
    LEIDCWDGSN | NDPVVYHGHT | LTSKITFCSV | IHVVDKYAFA | ASDYPVVLSL | 
    300:
    ENHCSTKQQE | RIAQYLLNIL | GDKLLTSPIG | DIEVTQLPSP | EALKFKILVK | 
    350:
    NKKCGTIEET | MLRKGRDSHG | ETGEVSEEEI | TSSDEETDEK | TPLYPKSGSS | 
    400:
    KRKSEGRSSP | PPRKKAKVKK | MKIAMGLSDL | VIYTKSEKFV | SFEHSLAHQK | 
    450:
    CYENNSIGEL | KAQKFVKHAA | NQFVSHTSRF | ITRIYPKGTR | AGSSNYNPQE | 
    500:
    FWNVGCQMVA | LNFQTSGTPM | ELQNGKFLDN | GGCGYILKPE | FLRNRNSTFN | 
    550:
    PHNVGRYSNP | LSLSIRLISG | HQLPPSNLSK | SNKADPLVQL | EIYGVPEDQA | 
    600:
    KRKSSVIKSN | ALSPRWDETF | SFTVQVPELA | LIRFCVQDEI | SLVANDFLGQ | 
    637:
    YTLPLLSLSK | GYCTVPLFSK | SGGKLEPASL | FVYVWYY
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    E15484h
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    E15484c
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    E15484m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    E15484r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    E15484b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    U15484m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    U15484h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    U15484r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    U15484c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    U15484b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    P15484Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Polyclonal Antibody for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Polyclonal Antibody for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    P15484Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Cat.:
    P15484Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Monoclonal Antibody for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Monoclonal Antibody for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Monoclonal Antibody for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Monoclonal Antibody for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Protein for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Protein for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Protein for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Protein for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
    Protein for Chicken 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "Phospholipase Czeta, the trigger of egg activation in mammals, is present in a non-mammalian species."
      Coward K. , Ponting C.P. , Chang H.-Y. , Hibbitt O. , Savolainen P. , Jones K.T. , Parrington J.
      Reproduction130:157-163(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
      tissue: Testis.
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