Gene name:
Pla2g6 (Pnpla9) ;
Protein name:
85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) ;
Alternative:
Intracellular membrane-associated calcium-independent phospholipase A2 beta (iPLA2-beta) ;Group VI phospholipase A2 (GVI PLA2) ;Patatin-like phospholipase domain-containing protein 9 (PNPLA9) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods.
Subcellular Location:
Isoform Short
Cytoplasm
Protein Attributes:
50:
MQFFGRLVNT | LSSVTNLFSN | PFRVKEVSLT | DYVSSERVRE | EGQLILLQNV |
100:
SNRTWDCVLV | SPRNPQSGFR | LFQLESEADA | LVNFQQFSSQ | LPPFYESSVQ |
150:
VLHVEVLQHL | TDLIRNHPSW | TVTHLAVELG | IRECFHHSRI | ISCANSTENE |
200:
EGCTPLHLAC | RKGDSEILVE | LVQYCHAQMD | VTDNKGETAF | HYAVQGDNPQ |
250:
VLQLLGKNAS | AGLNQVNNQG | LTPLHLACKM | GKQEMVRVLL | LCNARCNIMG |
300:
PGGFPIHTAM | KFSQKGCAEM | IISMDSNQIH | SKDPRYGASP | LHWAKNAEMA |
350:
RMLLKRGCDV | DSTSSSGNTA | LHVAVMRNRF | DCVMVLLTYG | ANAGARGEHG |
400:
NTPLHLAMSK | DNMEMVKALI | VFGAEVDTPN | DFGETPALIA | SKISKLITRK |
450:
ALLTLLKTVG | ADHHFPIIQG | VSTEQGSAAA | THPLFSLDRT | QPPAISLNNL |
500:
ELQDLMPISR | ARKPAFILSS | MRDEKRSHDH | LLCLDGGGVK | GLVIIQLLIA |
550:
IEKASGVATK | DLFDWVAGTS | TGGILALAIL | HSKSMAYMRG | VYFRMKDEVF |
600:
RGSRPYESGP | LEEFLKREFG | EHTKMTDVKK | PKVMLTGTLS | DRQPAELHLF |
650:
RNYDAPEAVR | EPRCNQNINL | KPPTQPADQL | VWRAARSSGA | APTYFRPNGR |
700:
FLDGGLLANN | PTLDAMTEIH | EYNQDMIRKG | QGNKVKKLSI | VVSLGTGKSP |
750:
QVPVTCVDVF | RPSNPWELAK | TVFGAKELGK | MVVDCCTDPD | GRAVDRARAW |
800:
CEMVGIQYFR | LNPQLGSDIM | LDEVSDAVLV | NALWETEVYI | YEHREEFQKL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Mouse CaI-PLA2
ELISA Kit for Mouse CaI-PLA2
ELISA Kit for Mouse CaI-PLA2
CLIA Kit for Mouse CaI-PLA2
CLIA Kit for Mouse CaI-PLA2
CLIA Kit for Mouse CaI-PLA2
Polyclonal Antibody for Mouse CaI-PLA2
Polyclonal Antibody for Mouse CaI-PLA2
Polyclonal Antibody for Mouse CaI-PLA2
Monoclonal Antibody for Mouse CaI-PLA2
Monoclonal Antibody for Mouse CaI-PLA2
Monoclonal Antibody for Mouse CaI-PLA2
Protein for Mouse CaI-PLA2
Protein for Mouse CaI-PLA2
Protein for Mouse CaI-PLA2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT)
strain :
DBA/2 .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION TO 2-3; 9; 11 AND 211
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG);ALTERNATIVE SPLICING;SUBCELLULAR LOCATION
strain :
NIH Swiss .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS LONG AND SHORT)
strain :
C57BL/6J .
strain :
FVB/N .
strain :
NMRI .
tissue :
Mammary tumor .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 479-491;IDENTIFICATION BY MASS SPECTROMETRY
strain :
OF1 .
tissue :
Hippocampus .