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Index > Protein center > PLVAP(Gene name) > Human
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  • PLVAP (Gene name),
  • Plasmalemma vesicle-associated protein (Protein name ),  PLVAP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    PLVAP(FELS;PV1);
    Protein name:
    Plasmalemma vesicle-associated protein;
    Alternative:
    Plasmalemma vesicle protein 1(PV-1);Fenestrated endothelial-linked structure protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability.
    Subcellular Location:
    Cell membrane Single-pass type II membrane protein Membrane caveola Single-pass type II membrane protein Cytoplasm perinuclear region Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region.
    Protein Attributes:
    Sequence length:
    442
    Sequence:
    50:
    MGLAMEHGGS | YARAGGSSRG | CWYYLRYFFL | FVSLIQFLII | LGLVLFMVYG | 
    100:
    NVHVSTESNL | QATERRAEGL | YSQLLGLTAS | QSNLTKELNF | TTRAKDAIMQ | 
    150:
    MWLNARRDLD | RINASFRQCQ | GDRVIYTNNQ | RYMAAIILSE | KQCRDQFKDM | 
    200:
    NKSCDALLFM | LNQKVKTLEV | EIAKEKTICT | KDKESVLLNK | RVAEEQLVEC | 
    250:
    VKTRELQHQE | RQLAKEQLQK | VQALCLPLDK | DKFEMDLRNL | WRDSIIPRSL | 
    300:
    DNLGYNLYHP | LGSELASIRR | ACDHMPSLMS | SKVEELARSL | RADIERVARE | 
    350:
    NSDLQRQKLE | AQQGLRASQE | AKQKVEKEAQ | AREAKLQAEC | SRQTQLALEE | 
    400:
    KAVLRKERDN | LAKELEEKKR | EAEQLRMELA | IRNSALDTCI | KTKSQPMMPV | 
    442:
    SRPMGPVPNP | QPIDPASLEE | FKRKILESQR | PPAGIPVAPS | SG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Plasmalemma vesicle-associated protein
    ELISA Kit for Human Plasmalemma vesicle-associated protein
    ELISA Kit for Human Plasmalemma vesicle-associated protein
    CLIA Kit for Human Plasmalemma vesicle-associated protein
    CLIA Kit for Human Plasmalemma vesicle-associated protein
    CLIA Kit for Human Plasmalemma vesicle-associated protein
    Polyclonal Antibody for Human Plasmalemma vesicle-associated protein
    Polyclonal Antibody for Human Plasmalemma vesicle-associated protein
    Polyclonal Antibody for Human Plasmalemma vesicle-associated protein
    Monoclonal Antibody for Human Plasmalemma vesicle-associated protein
    Monoclonal Antibody for Human Plasmalemma vesicle-associated protein
    Monoclonal Antibody for Human Plasmalemma vesicle-associated protein
    Protein for Human Plasmalemma vesicle-associated protein
    Protein for Human Plasmalemma vesicle-associated protein
    Protein for Human Plasmalemma vesicle-associated protein

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    References
    1. 1.
      "cDNA and protein sequence, genomic organization, and analysis of cis regulatory elements of mouse and human PLVAP genes."
      Stan R.-V. , Arden K.C. , Palade G.E.
      Genomics72:304-313(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
    2. 2.
      Mesak F.M. , Schoecklmann H. , Hallmann R.
      Submitted (2000-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
      tissue: Spleen.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lymph node.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: PNS.
    6. 6.
      "PV1 is a key structural component for the formation of the stomatal and fenestral diaphragms."
      Stan R.-V. , Tkachenko E. , Niesman I.R.
      Mol. Biol. Cell15:3615-3630(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
    7. 7.
      "Plasmalemmal vesicle-associated protein (PLVAP) is expressed by tumour endothelium and is upregulated by vascular endothelial growth factor-A (VEGF)."
      Strickland L.A. , Jubb A.M. , Hongo J.-A. , Zhong F. , Burwick J. , Fu L. , Frantz G.D. , Koeppen H.
      J. Pathol.206:466-475(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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