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Index > Protein center > PNP(Gene name) > Human
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  • PNP (Gene name),
  • Purine nucleoside phosphorylase (Protein name ),  PNPH_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PNP(NP);
    Protein name:
    Purine nucleoside phosphorylase(PNP);
    Alternative:
    Inosine-guanosine phosphorylase;Inosine phosphorylase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotrimer.
    Function:
    N/A
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    289
    Sequence:
    50:
    MENGYTYEDY | KNTAEWLLSH | TKHRPQVAII | CGSGLGGLTD | KLTQAQIFDY | 
    100:
    GEIPNFPRST | VPGHAGRLVF | GFLNGRACVM | MQGRFHMYEG | YPLWKVTFPV | 
    150:
    RVFHLLGVDT | LVVTNAAGGL | NPKFEVGDIM | LIRDHINLPG | FSGQNPLRGP | 
    200:
    NDERFGDRFP | AMSDAYDRTM | RQRALSTWKQ | MGEQRELQEG | TYVMVAGPSF | 
    250:
    ETVAECRVLQ | KLGADAVGMS | TVPEVIVARH | CGLRVFGFSL | ITNKVIMDYE | 
    289:
    SLEKANHEEV | LAAGKQAAQK | LEQFVSILMA | SIPLPDKAS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    MIM:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human PNP
    ELISA Kit for Human PNP
    ELISA Kit for Human PNP
    ELISA Kit for Human PNP
    CLIA Kit for Human PNP
    CLIA Kit for Human PNP
    CLIA Kit for Human PNP
    CLIA Kit for Human PNP
    Polyclonal Antibody for Human PNP
    Polyclonal Antibody for Human PNP
    Polyclonal Antibody for Human PNP
    Polyclonal Antibody for Human PNP
    Monoclonal Antibody for Human PNP
    Monoclonal Antibody for Human PNP
    Monoclonal Antibody for Human PNP
    Monoclonal Antibody for Human PNP
    Protein for Human PNP
    Protein for Human PNP
    Protein for Human PNP
    Protein for Human PNP

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human purine nucleoside phosphorylase cDNA sequence and genomic clone characterization."
      Williams S.R. , Goddard J.M. , Martin D.W. Jr.
      Nucleic Acids Res.12:5779-5787(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-51
    2. 2.
      "A human purine nucleoside phosphorylase deficiency caused by a single base change."
      Williams S.R. , Gekeler V. , McIvor R.S. , Martin D.W. Jr.
      J. Biol. Chem.262:2332-2338(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT PNPD LYS-89;VARIANT SER-51
    3. 3.
      "Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans."
      Yu L. , Kalla K. , Guthrie E. , Vidrine A. , Klimecki W.T.
      Environ. Health Perspect.111:1421-1427(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT SER-51
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-51
      tissue: Tongue.
    5. 5.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Ovary.
    8. 8.
      Bienvenut W.V. , Claeys D.
      Submitted (2006-02) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-22; 42-58; 68-76; 96-148; 212-229; 235-265 AND 271-287;ACETYLATION AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Platelet.
    9. 9.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "Assessment of the red cell proteome of young patients with unexplained hemolytic anemia by two-dimensional differential in-gel electrophoresis (DIGE)."
      von Lohneysen K. , Scott T.M. , Soldau K. , Xu X. , Friedman J.S.
      PLoS ONE7:E34237-E34237(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;SUBCELLULAR LOCATION
    13. 13.
      "Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2-A resolution."
      Ealick S.E. , Rule S.A. , Carter D.C. , Greenhough T.J. , Babu Y.S. , Cook W.J. , Habash J. , Helliwell J.R. , Stoeckler J.D. , Parks R.E. Jr. , Chen S.-F. , Bugg C.E.
      J. Biol. Chem.265:1812-1820(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS);FUNCTION
    14. 14.
      "Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency."
      Aust M.R. , Andrews L.G. , Barrett M.J. , Norby-Slycord C.J. , Markert M.L.
      Am. J. Hum. Genet.51:763-772(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SER-51;VARIANTS PNPD GLY-128 AND PRO-234
    15. 15.
      "Two novel missense and frameshift mutations in exons 5 and 6 of the purine nucleoside phosphorylase (PNP) gene in a severe combined immunodeficiency (SCID) patient."
      Pannicke U. , Tuchschmid P. , Friedrich W. , Bartram C.R. , Schwarz K.
      Hum. Genet.98:706-709(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PNPD CYS-192
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