Pou2f2 ELISA Kit for Mouse(Mus musculus) | EIAab.comPou2f2 ELISA Kit for Mouse(Mus musculus)

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Pou2f2 (Gene name),

POU domain, class 2, transcription factor 2 (Protein name ), PO2F2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Pou2f2(Oct2;Otf2);

Protein name:

POU domain, class 2, transcription factor 2;

Alternative:

Octamer-binding protein 2(Oct-2);Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2;Octamer-binding transcription factor 2(OTF-2);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.

Subcellular Location:

Cytoplasm Nucleus In alveolus epithelial cells of mammary glands, present in the nucleus and cytoplasm. In HC11 mammary epithelial cells, present in the nucleus and preinuclear regions.

Protein Attributes:

Sequence length:

463

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

463:

GPGLWWNPAP | YQP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q00196

String:

Q00196

UniGene:

Mm.76683

Pfam:

PF00046

KEGG:

mmu:18987

Uniprot:

Q00196

FOR

ELISA Kit for Mouse POU domain, class 2, transcription factor 2

Cat.:

E1527h

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Manual:

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Packing:

96T

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ELISA Kit for Mouse POU domain, class 2, transcription factor 2

Cat.:

E1527p

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MSDS:

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Packing:

96T

ELISA Kit for Mouse POU domain, class 2, transcription factor 2

Cat.:

E1527m

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Packing:

96T

CLIA Kit for Mouse POU domain, class 2, transcription factor 2

Cat.:

U1527h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Mouse POU domain, class 2, transcription factor 2

Cat.:

U1527p

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MSDS:

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Packing:

96T

CLIA Kit for Mouse POU domain, class 2, transcription factor 2

Cat.:

U1527m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse POU domain, class 2, transcription factor 2

Cat.:

P1527Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse POU domain, class 2, transcription factor 2

Cat.:

P1527Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse POU domain, class 2, transcription factor 2

Protein for Mouse POU domain, class 2, transcription factor 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same gene."
Hatzopoulos A.K. , Stoykova A.S. , Erselius J.R. , Goulding M.D. , Neuman T. , Gruss P.
Development109:349-362(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS OCT2.2 AND OCT2.5)
tissue: B-cell.
2.

"Multiple Oct2 isoforms are generated by alternative splicing."
Wirth T. , Priess A. , Annweiler A. , Zwilling S. , Oeler B.
Nucleic Acids Res.19:43-51(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS OCT2.1; OCT2.2; OCT2.3; OCT2.4; OCT2.5 AND OCT2.6);FUNCTION
tissue: Pre-B cell.
3.

"Expression of the Oct-2 transcription factor in mouse mammary gland and cloning and characterization of a novel Oct-2 isoform."
Dong B. , Zhao F.-Q.
Cell Tissue Res.328:595-606(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM OCT2.1);NUCLEOTIDE SEQUENCE [MRNA] OF 5-263 (ISOFORM OCT2.7);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain: C3H/HeN.
tissue: Mammary gland.
4.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: NOD.
tissue: Spleen.
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS OCT2.1 AND OCT2.3)
6.

"Short introns interrupting the Oct-2 POU domain may prevent recombination between POU family genes without interfering with potential POU domain 'shuffling' in evolution."
Matsuo K. , Clay O. , Kuenzler P. , Georgiev O. , Urbanek P. , Schaffner W.
Biol. Chem. Hoppe-Seyler375:675-683(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 167-361 (ISOFORM OCT2.2)
strain: 129/Sv.
7.

"Cloning and sequencing of POU-boxes expressed in mouse testis."
Goldsborough A. , Ashworth A. , Willison K.R.
Nucleic Acids Res.18:1634-1634(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 203-325 (ISOFORM OCT2.1)
strain: T6 / TW1.
tissue: Testis.
8.

"Interaction of Oct-binding transcription factors with a large series of 'noncanonical' oct-sequences. Primary sequence of murine Oct-2B cDNA."
Stepchenko A.G.
Dokl. Akad. Nauk SSSR325:175-178(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM OCT2.2)
9.

"Alternative splicing of the Oct-2 transcription factor RNA is differentially regulated in neuronal cells and B cells and results in protein isoforms with opposite effects on the activity of octamer/TAATGARAT-containing promoters."
Lillycrop K.A. , Latchman D.S.
J. Biol. Chem.267:24960-24965(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
10.

"Mini-Oct and Oct-2c: two novel, functionally diverse murine Oct-2 gene products are differentially expressed in the CNS."
Stoykova A.S. , Sterrer S. , Erselius J.R. , Hatzopoulos A.K. , Gruss P.
Neuron8:541-558(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING
11.

"Repression of a herpes simplex virus immediate-early promoter by the Oct-2 transcription factor is dependent on an inhibitory region at the N terminus of the protein."
Lillycrop K.A. , Dawson S.J. , Estridge J.K. , Gerster T. , Matthias P. , Latchman D.S.
Mol. Cell. Biol.14:7633-7642(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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