Gene name:
Pou5f1 (Oct-3;Oct-4;Otf-3;Otf3) ;
Protein name:
POU domain, class 5, transcription factor 1 ;
Alternative:
Octamer-binding protein 3 (Oct-3) ;NF-A3 ;Octamer-binding transcription factor 3 (OTF-3) ;Octamer-binding protein 4 (Oct-4) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with PKM2. Interacts with WWP2 (By similarity). Interacts with UBE2I and ZSCAN10.
Function:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Subcellular Location:
Nucleus
Expressed in a diffuse and slightly punctuate pattern.
Protein Attributes:
50:
MAGHLASDFA | FSPPPGGGDG | SAGLEPGWVD | PRTWLSFQGP | PGGPGIGPGS |
100:
EVLGISPCPP | AYEFCGGMAY | CGPQVGLGLV | PQVGVETLQP | EGQAGARVES |
150:
NSEGTSSEPC | ADRPNAVKLE | KVEPTPEESQ | DMKALQKELE | QFAKLLKQKR |
200:
ITLGYTQADV | GLTLGVLFGK | VFSQTTICRF | EALQLSLKNM | CKLRPLLEKW |
250:
VEEADNNENL | QEICKSETLV | QARKRKRTSI | ENRVRWSLET | MFLKCPKPSL |
300:
QQITHIANQL | GLEKDVVRVW | FCNRRQKGKR | SSIEYSQREE | YEATGTPFPG |
350:
GAVSFPLPPG | PHFGTPGYGS | PHFTTLYSVP | FPEGEAFPSV | PVTALGSPMH |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Bovine
Pig
ELISA Kit for Mouse POU domain, class 5, transcription factor 1
ELISA Kit for Mouse POU domain, class 5, transcription factor 1
ELISA Kit for Mouse POU domain, class 5, transcription factor 1
ELISA Kit for Mouse POU domain, class 5, transcription factor 1
CLIA Kit for Mouse POU domain, class 5, transcription factor 1
CLIA Kit for Mouse POU domain, class 5, transcription factor 1
CLIA Kit for Mouse POU domain, class 5, transcription factor 1
CLIA Kit for Mouse POU domain, class 5, transcription factor 1
Polyclonal Antibody for Mouse POU domain, class 5, transcription factor 1
Polyclonal Antibody for Mouse POU domain, class 5, transcription factor 1
Polyclonal Antibody for Mouse POU domain, class 5, transcription factor 1
Polyclonal Antibody for Mouse POU domain, class 5, transcription factor 1
Monoclonal Antibody for Mouse POU domain, class 5, transcription factor 1
Monoclonal Antibody for Mouse POU domain, class 5, transcription factor 1
Monoclonal Antibody for Mouse POU domain, class 5, transcription factor 1
Monoclonal Antibody for Mouse POU domain, class 5, transcription factor 1
Protein for Mouse POU domain, class 5, transcription factor 1
Protein for Mouse POU domain, class 5, transcription factor 1
Protein for Mouse POU domain, class 5, transcription factor 1
Protein for Mouse POU domain, class 5, transcription factor 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
tissue :
Embryonic carcinoma .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INDUCTION
tissue :
Embryonic carcinoma .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];SEQUENCE REVISION;INDUCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Embryo .
6.
"Inhibition of DNA binding of Sox2 by the SUMO conjugation."
Tsuruzoe S.
,
Ishihara K.
,
Uchimura Y.
,
Watanabe S.
,
Sekita Y.
,
Aoto T.
,
Saitoh H.
,
Yuasa Y.
,
Niwa H.
,
Kawasuji M.
,
Baba H.
,
Nakao M.
Biochem. Biophys. Res. Commun.351:920-926(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUMOYLATION AT LYS-118;MUTAGENESIS OF LYS-118
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : BIOTECHNOLOGY
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUMOYLATION AT LYS-118;MUTAGENESIS OF LYS-118; GLU-120; LYS-215 AND LYS-244;FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH UBE2I
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUMOYLATION AT LYS-118;MUTAGENESIS OF LYS-118;FUNCTION;SUBCELLULAR LOCATION
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ZSCAN10
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : UBIQUITINATION
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF POU DOMAIN