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Index > Protein center > Pou5f1(Gene name) > Mouse
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  • Pou5f1 (Gene name),
  • POU domain, class 5, transcription factor 1 (Protein name ),  PO5F1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Pou5f1(Oct-3;Oct-4;Otf-3;Otf3);
    Protein name:
    POU domain, class 5, transcription factor 1;
    Alternative:
    Octamer-binding protein 3(Oct-3);NF-A3;Octamer-binding transcription factor 3(OTF-3);Octamer-binding protein 4(Oct-4);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with PKM2. Interacts with WWP2 (By similarity). Interacts with UBE2I and ZSCAN10.
    Function:
    Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
    Subcellular Location:
    Nucleus Expressed in a diffuse and slightly punctuate pattern.
    Protein Attributes:
    Sequence length:
    352
    Sequence:
    50:
    MAGHLASDFA | FSPPPGGGDG | SAGLEPGWVD | PRTWLSFQGP | PGGPGIGPGS | 
    100:
    EVLGISPCPP | AYEFCGGMAY | CGPQVGLGLV | PQVGVETLQP | EGQAGARVES | 
    150:
    NSEGTSSEPC | ADRPNAVKLE | KVEPTPEESQ | DMKALQKELE | QFAKLLKQKR | 
    200:
    ITLGYTQADV | GLTLGVLFGK | VFSQTTICRF | EALQLSLKNM | CKLRPLLEKW | 
    250:
    VEEADNNENL | QEICKSETLV | QARKRKRTSI | ENRVRWSLET | MFLKCPKPSL | 
    300:
    QQITHIANQL | GLEKDVVRVW | FCNRRQKGKR | SSIEYSQREE | YEATGTPFPG | 
    350:
    GAVSFPLPPG | PHFGTPGYGS | PHFTTLYSVP | FPEGEAFPSV | PVTALGSPMH | 
    352:
    SN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse POU domain, class 5, transcription factor 1
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    E1533m
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    96T
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    ELISA Kit for Mouse POU domain, class 5, transcription factor 1
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    E1533h
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    96T
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    ELISA Kit for Mouse POU domain, class 5, transcription factor 1
    Cat.:
    E1533b
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    Packing:
    96T
    ELISA Kit for Mouse POU domain, class 5, transcription factor 1
    Cat.:
    E1533p
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    Packing:
    96T
    CLIA Kit for Mouse POU domain, class 5, transcription factor 1
    Cat.:
    U1533b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse POU domain, class 5, transcription factor 1
    Cat.:
    U1533h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse POU domain, class 5, transcription factor 1
    Cat.:
    U1533m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse POU domain, class 5, transcription factor 1
    Cat.:
    U1533p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse POU domain, class 5, transcription factor 1
    Cat.:
    P1533Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse POU domain, class 5, transcription factor 1
    Cat.:
    P1533Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse POU domain, class 5, transcription factor 1
    Polyclonal Antibody for Mouse POU domain, class 5, transcription factor 1
    Monoclonal Antibody for Mouse POU domain, class 5, transcription factor 1
    Monoclonal Antibody for Mouse POU domain, class 5, transcription factor 1
    Monoclonal Antibody for Mouse POU domain, class 5, transcription factor 1
    Monoclonal Antibody for Mouse POU domain, class 5, transcription factor 1
    Protein for Mouse POU domain, class 5, transcription factor 1
    Protein for Mouse POU domain, class 5, transcription factor 1
    Protein for Mouse POU domain, class 5, transcription factor 1
    Protein for Mouse POU domain, class 5, transcription factor 1

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    Precision
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    Linearity
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    References
    1. 1.
      "A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo."
      Rosner M.H. , Vigano M.A. , Ozato K. , Timmons P.M. , Poirier F. , Rigby P.W.J. , Staudt L.
      Nature345:686-692(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
      tissue: Embryonic carcinoma.
    2. 2.
      "New type of POU domain in germ line-specific protein Oct-4."
      Schoeler H.R. , Ruppert S. , Suzuki N. , Chowdhury K. , Gruss P.
      Nature344:435-439(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INDUCTION
      tissue: Embryonic carcinoma.
    3. 3.
      "A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells."
      Okamoto K. , Okazawa H. , Okuda A. , Sakai M. , Muramatsu M. , Hamada H.
      Cell60:461-472(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "The oct3 gene, a gene for an embryonic transcription factor, is controlled by a retinoic acid repressible enhancer."
      Okazawa H. , Okamoto K. , Ishino F. , Ishino-Kaneko T. , Takeda S. , Toyoda Y. , Muramatsu M. , Hamada H.
      EMBO J.10:2997-3005(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];SEQUENCE REVISION;INDUCTION
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Embryo.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-118;MUTAGENESIS OF LYS-118
    7. 7.
      "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors."
      Takahashi K. , Yamanaka S.
      Cell126:663-676(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: BIOTECHNOLOGY
    8. 8.
      "Post-translational modification of POU domain transcription factor Oct-4 by SUMO-1."
      Zhang Z. , Liao B. , Xu M. , Jin Y.
      FASEB J.21:3042-3051(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-118;MUTAGENESIS OF LYS-118; GLU-120; LYS-215 AND LYS-244;FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH UBE2I
    9. 9.
      "Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation."
      Wei F. , Schoeler H.R. , Atchison M.L.
      J. Biol. Chem.282:21551-21560(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-118;MUTAGENESIS OF LYS-118;FUNCTION;SUBCELLULAR LOCATION
    10. 10.
      "Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells."
      Yu H.B. , Kunarso G. , Hong F.H. , Stanton L.W.
      J. Biol. Chem.284:31327-31335(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZSCAN10
    11. 11.
      "Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner."
      Liao B. , Jin Y.
      Cell Res.20:332-344(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION
    12. 12.
      "Secondary structure of the oct-3 POU homeodomain as determined by 1H-15N NMR spectroscopy."
      Morita E.H. , Shirakawa M. , Hayashi F. , Imagawa M. , Kyogoku Y.
      FEBS Lett.321:107-110(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF POU DOMAIN
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