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Index > Protein center > BVES(Gene name) > Chicken
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  • BVES (Gene name),
  • Blood vessel epicardial substance (Protein name ),  POPD1_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    BVES(POP1;POPDC1);
    Protein name:
    Blood vessel epicardial substance;
    Alternative:
    Popeye domain-containing protein 1(Popeye protein 1);
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Homodimer. Homodimerization requires the C-terminus cytoplasmic region.
    Function:
    Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Involved in epithelial movement during corneal sheet formation and regeneration. May play a role in VAMP3-mediated vesicular transport and recycling of receptor molecules. May play a role in the regulation of cell shape and movement by modulating the Rho-GTPase activity. May also be involved in striated muscle regeneration and in the regulation of cell spreading.
    Subcellular Location:
    Lateral cell membrane Cell junction tight junction Membrane Multi-pass membrane protein Detected at points of cell-cell contact in confluent epithelial sheets. Colocalizes with components of the adherens and tight junctions.
    Protein Attributes:
    Sequence length:
    357
    Sequence:
    50:
    MDTTAISPLT | PLGVIPDLKN | ATSVPFNETA | CENWKEIHHL | VFHVANICFA | 
    100:
    AGLVIPTTLN | LHMIFLRGLL | TVGCALFIIW | ATLYRCALDI | MIWNSVFLVV | 
    150:
    NLLHFIYLVY | KRRPIKIEKE | LSSLYKRMFE | PLHVPPELFQ | RLTGQFCNIQ | 
    200:
    TLKTGQAYAA | EDKTSVDDRL | SILLKGKMKV | SYRGHFLHNI | YPCAFIDSPE | 
    250:
    FRSTQMNRGE | KFQVTIIADD | NCKFLCWSRE | RLTYFLETEP | FLYEIFKYLI | 
    300:
    GKDITNKLYS | LNDPTLNDKA | SKKIDRQPSL | CSQLSVMQMR | NSMASTSDSE | 
    350:
    DGLQMFLRGT | SSSSSLRPGR | TSPYLRTSAK | MKPIEESVED | DVFEAPSAEK | 
    357:
    LELQRLP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken Blood vessel epicardial substance
    ELISA Kit for Chicken Blood vessel epicardial substance
    ELISA Kit for Chicken Blood vessel epicardial substance
    ELISA Kit for Chicken Blood vessel epicardial substance
    ELISA Kit for Chicken Blood vessel epicardial substance
    CLIA Kit for Chicken Blood vessel epicardial substance
    CLIA Kit for Chicken Blood vessel epicardial substance
    CLIA Kit for Chicken Blood vessel epicardial substance
    CLIA Kit for Chicken Blood vessel epicardial substance
    CLIA Kit for Chicken Blood vessel epicardial substance
    Polyclonal Antibody for Chicken Blood vessel epicardial substance
    Polyclonal Antibody for Chicken Blood vessel epicardial substance
    Polyclonal Antibody for Chicken Blood vessel epicardial substance
    Polyclonal Antibody for Chicken Blood vessel epicardial substance
    Polyclonal Antibody for Chicken Blood vessel epicardial substance
    Monoclonal Antibody for Chicken Blood vessel epicardial substance
    Monoclonal Antibody for Chicken Blood vessel epicardial substance
    Monoclonal Antibody for Chicken Blood vessel epicardial substance
    Monoclonal Antibody for Chicken Blood vessel epicardial substance
    Monoclonal Antibody for Chicken Blood vessel epicardial substance
    Protein for Chicken Blood vessel epicardial substance
    Protein for Chicken Blood vessel epicardial substance
    Protein for Chicken Blood vessel epicardial substance
    Protein for Chicken Blood vessel epicardial substance
    Protein for Chicken Blood vessel epicardial substance

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    References
    1. 1.
      "bves: a novel gene expressed during coronary blood vessel development."
      Reese D.E. , Zavaljevski M. , Streiff N.L. , Bader D.
      Dev. Biol.209:159-171(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
      tissue: Heart.
    2. 2.
      "Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart."
      Andree B. , Hillemann T. , Kessler-Icekson G. , Schmitt-John T. , Jockusch H. , Arnold H.-H. , Brand T.
      Dev. Biol.223:371-382(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4);NUCLEOTIDE SEQUENCE [MRNA] OF 37-357 (ISOFORM 2);TISSUE SPECIFICITY
    3. 3.
      "Bves is expressed in the epithelial components of the retina, lens, and cornea."
      Ripley A.N. , Chang M.S. , Bader D.M.
      Invest. Ophthalmol. Vis. Sci.45:2475-2483(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    4. 4.
      "Bves modulates epithelial integrity through an interaction at the tight junction."
      Osler M.E. , Chang M.S. , Bader D.M.
      J. Cell Sci.118:4667-4678(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    5. 5.
      "Identification of a novel intracellular interaction domain essential for Bves function."
      Kawaguchi M. , Hager H.A. , Wada A. , Koyama T. , Chang M.S. , Bader D.M.
      PLoS ONE3:E2261-E2261(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HOMODIMER;SUBCELLULAR LOCATION;MUTAGENESIS OF LYS-272 AND LYS-273
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