Gene name:
BVES (POP1;POPDC1) ;
Protein name:
Blood vessel epicardial substance ;
Alternative:
Popeye domain-containing protein 1 (Popeye protein 1) ;
Organism:
Chicken (Gallus gallus).
General Annotation
Sub Unit:
Homodimer. Homodimerization requires the C-terminus cytoplasmic region.
Function:
Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Involved in epithelial movement during corneal sheet formation and regeneration. May play a role in VAMP3-mediated vesicular transport and recycling of receptor molecules. May play a role in the regulation of cell shape and movement by modulating the Rho-GTPase activity. May also be involved in striated muscle regeneration and in the regulation of cell spreading.
Subcellular Location:
Lateral cell membrane
Cell junction
tight junction
Membrane
Multi-pass membrane protein
Detected at points of cell-cell contact in confluent epithelial sheets. Colocalizes with components of the adherens and tight junctions.
Protein Attributes:
50:
MDTTAISPLT | PLGVIPDLKN | ATSVPFNETA | CENWKEIHHL | VFHVANICFA |
100:
AGLVIPTTLN | LHMIFLRGLL | TVGCALFIIW | ATLYRCALDI | MIWNSVFLVV |
150:
NLLHFIYLVY | KRRPIKIEKE | LSSLYKRMFE | PLHVPPELFQ | RLTGQFCNIQ |
200:
TLKTGQAYAA | EDKTSVDDRL | SILLKGKMKV | SYRGHFLHNI | YPCAFIDSPE |
250:
FRSTQMNRGE | KFQVTIIADD | NCKFLCWSRE | RLTYFLETEP | FLYEIFKYLI |
300:
GKDITNKLYS | LNDPTLNDKA | SKKIDRQPSL | CSQLSVMQMR | NSMASTSDSE |
350:
DGLQMFLRGT | SSSSSLRPGR | TSPYLRTSAK | MKPIEESVED | DVFEAPSAEK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Pig
Mouse
Chicken
Human
Rat
ELISA Kit for Chicken Blood vessel epicardial substance
ELISA Kit for Chicken Blood vessel epicardial substance
ELISA Kit for Chicken Blood vessel epicardial substance
ELISA Kit for Chicken Blood vessel epicardial substance
ELISA Kit for Chicken Blood vessel epicardial substance
CLIA Kit for Chicken Blood vessel epicardial substance
CLIA Kit for Chicken Blood vessel epicardial substance
CLIA Kit for Chicken Blood vessel epicardial substance
CLIA Kit for Chicken Blood vessel epicardial substance
CLIA Kit for Chicken Blood vessel epicardial substance
Polyclonal Antibody for Chicken Blood vessel epicardial substance
Polyclonal Antibody for Chicken Blood vessel epicardial substance
Polyclonal Antibody for Chicken Blood vessel epicardial substance
Polyclonal Antibody for Chicken Blood vessel epicardial substance
Polyclonal Antibody for Chicken Blood vessel epicardial substance
Monoclonal Antibody for Chicken Blood vessel epicardial substance
Monoclonal Antibody for Chicken Blood vessel epicardial substance
Monoclonal Antibody for Chicken Blood vessel epicardial substance
Monoclonal Antibody for Chicken Blood vessel epicardial substance
Monoclonal Antibody for Chicken Blood vessel epicardial substance
Protein for Chicken Blood vessel epicardial substance
Protein for Chicken Blood vessel epicardial substance
Protein for Chicken Blood vessel epicardial substance
Protein for Chicken Blood vessel epicardial substance
Protein for Chicken Blood vessel epicardial substance
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
tissue :
Heart .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4);NUCLEOTIDE SEQUENCE [MRNA] OF 37-357 (ISOFORM 2);TISSUE SPECIFICITY
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : HOMODIMER;SUBCELLULAR LOCATION;MUTAGENESIS OF LYS-272 AND LYS-273