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Index > Protein center > BVES(Gene name) > Pig
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  • BVES (Gene name),
  • Blood vessel epicardial substance (Protein name ),  POPD1_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    BVES(POP1;POPDC1);
    Protein name:
    Blood vessel epicardial substance;
    Alternative:
    Popeye domain-containing protein 1(Popeye protein 1);
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Homodimer. Homodimerization requires the C-terminus cytoplasmic region. Interacts (via the C-terminus cytoplasmic tail) with TJP1. Interacts (via the C-terminus cytoplasmic tail) with ARHGEF25/GEFT (via the DH domain). Interacts (via the C-terminus cytoplasmic tail) with VAMP3.
    Function:
    Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading.
    Subcellular Location:
    Lateral cell membrane Cell junction tight junction Membrane Multi-pass membrane protein Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Detected at cell-cell contact but never observed at the free surface of epithelial cells. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle.
    Protein Attributes:
    Sequence length:
    360
    Sequence:
    50:
    MNYTESSPLA | ESTAIGFTPE | LGSITPVPSN | ETTCENWREI | HHLVFHVANV | 
    100:
    FFAIGLVLPT | TLHLHMILLR | GMLTIGCTLY | IVWATLYRCA | LDIMIWNSVF | 
    150:
    LGINVLHLSY | LLYKKRPVKI | EKELKGIYQR | LFEPLRVPPD | LFKRLTGQFC | 
    200:
    MIQTLKKGQA | YAAEDKTSVD | DRLSILLKGK | MKVSYRGHFL | HNIYPCAFID | 
    250:
    SPEFRSTQMH | KGEKFQVTII | ADDNCRFLCW | SRERLTYFLE | SEPFLYEVFR | 
    300:
    YLIGKDITNK | LYSLNDPTLN | DKTIKKLDHQ | LSLCTQLSML | EMRNSIVSTS | 
    350:
    DSEDGLHQFL | RGTSSVSSLY | VPSPHQRASA | KMKPIEEGVE | DDDEVFEPET | 
    360:
    PNTFKVRQLP | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Pig Blood vessel epicardial substance
    ELISA Kit for Pig Blood vessel epicardial substance
    ELISA Kit for Pig Blood vessel epicardial substance
    ELISA Kit for Pig Blood vessel epicardial substance
    ELISA Kit for Pig Blood vessel epicardial substance
    CLIA Kit for Pig Blood vessel epicardial substance
    CLIA Kit for Pig Blood vessel epicardial substance
    CLIA Kit for Pig Blood vessel epicardial substance
    CLIA Kit for Pig Blood vessel epicardial substance
    CLIA Kit for Pig Blood vessel epicardial substance
    Polyclonal Antibody for Pig Blood vessel epicardial substance
    Polyclonal Antibody for Pig Blood vessel epicardial substance
    Polyclonal Antibody for Pig Blood vessel epicardial substance
    Polyclonal Antibody for Pig Blood vessel epicardial substance
    Polyclonal Antibody for Pig Blood vessel epicardial substance
    Monoclonal Antibody for Pig Blood vessel epicardial substance
    Monoclonal Antibody for Pig Blood vessel epicardial substance
    Monoclonal Antibody for Pig Blood vessel epicardial substance
    Monoclonal Antibody for Pig Blood vessel epicardial substance
    Monoclonal Antibody for Pig Blood vessel epicardial substance
    Protein for Pig Blood vessel epicardial substance
    Protein for Pig Blood vessel epicardial substance
    Protein for Pig Blood vessel epicardial substance
    Protein for Pig Blood vessel epicardial substance
    Protein for Pig Blood vessel epicardial substance

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    References
    1. 1.
      "The porcine popeye domain containing genes: molecular cloning, identification of alternative splicing, mapping and muscle-specific expression analysis."
      Liu B. , Peng Y.
      Submitted (2007-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
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